Kai-Ting Shade

Everyone who intends to join or lead a research group should read the essay by Bruno Lemaitre: An Essay on Science and Narcissism: How do high-ego personalities drive research in life sciences? (Usually available for free download; do a google search)

Sky 5 is over a fire that has engulfed a large home on a golf course in Topsfield, Massachusetts twitter.com/i/broadcasts/1…

@itchdoctor Agree that we absolutely need to understand more!! Potentially hyperactivation TRPM8 (for cold induced CSU) too?

It absolutely blows my mind that chronic inducible #urticaria is thought to be caused by #cold #heat #pressure #water #sunlight #vibration and how little the molecular framework of #somatosensation has been invoked in its physiology. #neuroimmune #ionchannels #TRPV1 #TRPA1 #Piezo

Super interesting!! As b-hex release is commonly used for measuring mast cell degranulation. What does this mean in case of diseases involving mast cell activation e.g. food allergy? 🤔

With @regeneron, we’re announcing the first positive Phase 3 trial in children 1 to 11 years of age with eosinophilic esophagitis - a painful disease that can impact growth and development: sanofi.com/en/media-room/…

TLRs never stop teaching us about host-pathogen interactions. Madhani et al reveal a fungal ligand for TLR4 that drives allergic inflammation. Congrats to the authors on this important discovery. @hitenmadhani nature.com/articles/s4158…

A new analysis of biopsies from patients with acne reveal a unique pathway between TREM2 macrophages, squalene, and C. acnes – supporting benzoyl peroxide as a treatment for the disease. @dgsomucla @UCLA fcld.ly/kbceeet

We believe that parental leave should be equal for all parents. From January 2022, any Sanofi employee in any country will get a minimum of 14 weeks paid parental leave - that includes birth parents, adoptive parents, and surrogate parents! 🎉

Wow - cancer patients who took certain anti-histamine medications because of allergies responded better to immunotherapy. Turns out histamine binds to macrophage receptors, makes macrophages immunosuppressive, thus inducing T cell dysfunction cell.com/cancer-cell/fu…

Decoding #glycotime in the news @Nature media.nature.com/original/magaz…

A new book by Philipp Dettmer, creator of @Kurz_Gesagt, charts the vast array of different immune cells, what they do, the way they communicate with each other, and what happens when things go wrong. Read the review from @SciMagBooks: fcld.ly/thzqbz1

Just as we predicted! #sciencematters #itch Dupixent® (dupilumab) is the First Biologic to Significantly Reduce Itch and Skin Lesions in Phase 3 Trial for Prurigo Nodularis, Demonstrating the Role of Type 2 Inflammation in this Disease prnewswire.com/news-releases/…

Join us for Xinzhong Dong from @HHMINEWS @HopkinsMedicine Nicholas Gaudenzio from @Inserm and @meconroy22 from @MassGeneralNews on #neuroimmune #mastcell #skin #itch

A fantastic postdoc position is available in Jim Moon's lab at @MGHRI and @harvardmed examining #tcell responses to #SARSCoV2 and #vaccines. This is part of a highly collaborative NIH program spread across several labs in the Boston area nature.com/naturecareers/…

Pre-colonization Glass Gem Corn, Indigenous to North America, regrown by a Cherokee farmer in Oklahoma. This particular corn is a mix of ancient Pawnee, Osage and Cherokee varieties.

Want to join an amazing team studying how sensory neurons initiate allergies and other immune-mediated diseases? The Sokol Lab in Boston (at @MGH_RI @harvardmed @broadinstitute) is looking for a new postdoc! Come join us!

"Don’t get me wrong. We need data produced from new technologies to advance understanding. But this is only the first step." go.nature.com/3k9EcSZ

Another major advance for #itch #pruritus the central symptom in #urticaria #hives moving beyond #antihistamines and anti-IgE globenewswire.com/news-release/2…

In this comment piece, I discuss the importance of examining tissues for understanding human immune responses and strategies for sample acquisition @nature @Columbia_MI @ColumbiaSurgery @Columbiamed

@DrAkshayNair @jonroiser @MasudHusain @UCLHD @profgeraintrees @RobbRutledge Congratulations!

#Phd Viva passed 🎉 🎉 Thanks to @jonroiser and @MasudHusain for the viva! Also thanks to my supervisors Sarah T @UCLHD @profgeraintrees and @RobbRutledge #drsquared