Istesso

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Istesso

Istesso

@istesso

Restoring repair for lifelong health

London, UK Katılım Ekim 2012
9 Takip Edilen129 Takipçiler
Istesso
Istesso@istesso·
New data show that Istesso’s first-in-class oral regenerative medicine, leramistat, can restore and even enhance muscle quality and strength in models of aging and chronic disease. Is this the beginning of the end for age-related muscle loss? istesso.co.uk/news-press/
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Lisa
Lisa@DrugDiscoverer·
Lower gravity, more radiation= more cellular stress, muscle and bone loss (and bone loss doesn’t recover fully on return to earth). To populate moon cities we’ll need medicines that protect muscle and bone, and health, together. @istesso
Elon Musk@elonmusk

@luismbat The Moon is faster to make a self-growing city. If civilization continues to grow, we will figure out the universe. If not, nothing else matters.

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Lisa
Lisa@DrugDiscoverer·
@vkhosla @Vero_Bioscience The logical next step if these clocks can predict organ aging is to prevent deterioration before diagnosis by adaptive repair to restore function. @istesso
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Lisa
Lisa@DrugDiscoverer·
Changes map to areas of failed repair… and drive aging, but is it the epigenetic change that drives the failed repair, or failure to repair that drives the epigenetics? And what happens when we restore capacity to repair? @istesso
Prof Steve Horvath@prof_horvath

Single-cell epigenome atlas identifies kidney epithelial cells as a driver of epigenetic aging. Lake et al. (2026) build a cross-species atlas showing that aging is driven by collapse of 3D chromatin structure in tubular epithelia. Beautiful multi-omic work. biorxiv.org/content/10.648…

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Lisa
Lisa@DrugDiscoverer·
Today our team @istesso publish data showing that we can elicit tissue repair in models of autoinflammation/immunity and fibrosis via a single metabolic switch.
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Istesso
Istesso@istesso·
This RA Awareness Week we are supporting @NRAS_UK to shine a light on #RheumatoidArthritis and the devastating impact #RAdrain has on patients’ everyday lives. We agree everyone should be able to live the life they want to live without pain.
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Istesso
Istesso@istesso·
On our way to the London Stock Exchange where our CEO Lisa Patel will be presenting Istesso as part of the ‘Future of Healthcare Investment Forum 2023’. We're honoured to be invited and look forward to bringing important conversations to the table regarding healthcare.
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Istesso
Istesso@istesso·
Last week’s annual EULAR Congress offered a vital forum to discuss rheumatic diseases 🧬 Lots of important questions were asked, highlighting the need to support patients more. We’re still a way off where we need to be, but it’s great to see progress.
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Istesso
Istesso@istesso·
Last night we celebrated 20 years of @IPGroupplc's outstanding support for science and innovation @sciencemuseum. Istesso’s Executive Chair, @biotech_CEO, led a panel discussion with inspiring speakers including Dame Kate Bingham and Maggie Aderin-Pocock MBE #sciencematters
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Istesso
Istesso@istesso·
Our CEO Lisa Patel recently spoke to Tom Froggatt for his Careers in Discovery podcast. To hear all about Lisa’s story, what motivates her and some fascinating insights into how Istesso came to be, head over to the news page on our website where you can find the link in full.
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Parkwalk
Parkwalk@ParkwalkAdvisor·
To celebrate Intl Women’s Day 2021, we wanted to highlight 3 of our portfolio co's who are led by successful females. Read our interviews with Giorgia Longobardi, CEO, Cambridge GaN + Jane Osbourn, Chair, @Mogrify_UK + Lisa Patel, CSO @istesso bit.ly/3rtrkrU #IWD2021
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Istesso
Istesso@istesso·
Clinical trials are the lifeblood of new medicines. Thank you to all our partners for supporting and facilitating ours. #Clinicaltrialsday
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Istesso
Istesso@istesso·
Looking forward to welcoming Team MBS to the house today and discussing some exciting science
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