Tapasree Roy Sarkar (Sarkar Lab)

We (Biology, Statistics and Health Science Center of Texas A&M University)are hosting a symposium on ‘Cancer: Basic Science to Bioinformatics’. Free registration @ https:/iamcs.tamu.edu/4th-annual-bioinformatics-symposium/. With @SenduraiMani @tarumurmur @irtisha_singh

A groundbreaking study from the lab of Dr. Tapasree Roy Sarkar was recently highlighted in Forbes Magazine, for identifying the critical link between circadian rhythm disruption (CRD) and breast cancer. Read the full article from Forbes here: tx.ag/forbesroysarkar

Disrupted Circadian Rhythms Fuel Aggressive Breast Cancer Disrupted circadian rhythms from night shifts or irregular sleep schedules can fuel breast cancer risk. Working the night shift, frequently flying across time zones or keeping an irregular sleep schedule does more than just leave us exhausted; it can fuel the risk of aggressive breast cancer. Exactly how and why this happens has remained a mystery, until now. A new study sheds light on this elusive link, finding that circadian disruptions change the structure of mammary glands and weaken the immune system’s defenses, all the while pointing toward a new way to counteract these effects. To investigate these effects, the researchers used two groups of genetically engineered models that develop aggressive breast cancer. One group lived on a normal night-day schedule, while the other lived on a disrupted light cycle that threw off their internal clocks. The findings, published in Nature group journal Oncogene, were striking. Typical models develop cancer around the 22-week marker. The circadian-disrupted group, however, showed signs of cancer much earlier — at almost 18 weeks. Tumors in circadian-disrupted models were also far more aggressive, and far more likely to spread to the lungs, a key indicator of poor outcomes in breast cancer patients. Source in comments.

Circadian disruption alters mammary gland morphology and accelerates aggressive mammary tumorigenesis #oncogene #nature

@MaraShermanLab @TheMarkFdn Congratulations, Mara!!!

Huge thanks to @TheMarkFdn for supporting this new chapter in our #pancreaticcancer research effort. Congrats to fellow grantees - honored to be in your company!

Women’s Health, Breast Cancer Awareness Month, Oct’24: Invited talk @nVent Global Women’s Network #BreastCancerAwareness #BreastCancerAwarenessMonth #BreastCancer

#latepost Had a great time visiting Vanderbilt university as a SEC scholar … Thanks @marjanrafat for being an amazing host!

Symposium ‘Cancer Research: Basic science to Bioinformatics’, on Oct 11th, at Texas A&M University, with @TAMU_Biology @TAMUArtSci @AlexCarlKeene @mahulchak @Irtisha_Singh @TAMUstats

@SGoswamiMDPhD @DeblinaRC @RaiPratishtha @MDAndersonNews Congratulations!!!

I am happy to share the latest paper from Goswami_Lab in Nature Immunology. We showed the integration of metabolic & epigenetic pathways regulating CD8 T cell mediated anti tumor immunity via histone lactylation. ⁦@DeblinaRC⁩⁦@RaiPratishtha⁩⁦@MDAndersonNews⁩

@RafatLab Thank you so much for hosting me.. I had a great time!!! Thoroughly enjoyed our brainstorming session… and our sweet treats 😄

We thoroughly enjoyed Dr. Tapasree Sarkar’s visit through the SEC Faculty Travel Award! She shared her exciting work, and we had a few awesome brainstorming sessions. We look forward to working with you in the future! @itsTaps

@RafatLab 😄😄😄

Not pictured: fun meeting w/students, meeting with colleagues, the VICC Breast Cancer Research Program meeting, and trying not to get soaked!

@AKGaharwar @Irtisha_Singh @NatureComms @Kanwar_Abhay08 @tamusystem @TEESresearch @tamucommedsci @MITOCHONDRIAMED @Mito_News @MitoAging @BMESociety @bmentamu Congratulations @AKGaharwar @Irtisha_Singh and team

Excited to share our recent work on "Recharging Mitochondria", published in @NatureComms. This work introduces a unique concept of "atomic vacancies" in nanoparticles, to boost mitochondrial biogenesis and bioenergetics. #Mitochondria #AgeRelatedDisorders rdcu.be/dUbcW

@ola_jhumie Congratulations!! So proud of you 🤗🤗🤗

I’m a PhD candidate. I can’t put into words how I feel but I’m certain God’s grace is true. I’m also blessed to have the most amazing mentor @itsTaps, thank you for the support. Thank you to the Sarkar lab 🥰

Thank you so much, Dr. Simon, for visiting us and for the wonderful seminar!!! @TAMU_Biology @PennMedicine @TAMUArtSci

So excited to host Dr. Celeste Simon from #upenn #upenmedicine #tamubiology on Sept 10th.

It was a wonderful experience presenting my research at the mechanisms & models of cancer meeting @CSHL. Thank you to my amazing mentor @itsTaps and @TAMU_Biology. I also met the wonderful @PamSharmaMDPhD, and enjoyed her talk on immune checkpoint therapy. #cshlcancer24 #phdlife

@ola_jhumie @CSHL @TAMU_Biology @PamSharmaMDPhD So proud of you Ola!

@NinaSteele17 @Momademia Congratulations!!!

Achievement 🔓The first manuscript from the Steele lab was submitted this afternoon. All after starting up lab in pandemic, having a baby, nearly dying from a daycare illness and divorce.. Huge team effort to get it across finish line 🙏🏼 grateful for our awesome team! @Momademia

@RonDePinho So sorry to hear your loss. My condolences to you and your family!!

Love you mom. God bless you and give our love to Dad. ♥️ ballarddurand.com/obituaries/mar…

Congratulations to Tapasree Roy Sarkar on her SEC Faculty Travel Program Grant, where she'll be visiting Vanderbilt School of Medicine to collaborate & share her work on how different environmental factors, biological cues, & therapy can alter the breast tumor microenvironment!

@NinaSteele17 @Momademia Congratulations!!best wishes

I submitted my first R01 + signed divorce papers today. What a day… I can say when I set out to start my lab this was not what I anticipated submitting my first big grant but I’m so proud of my team and the whole center in supporting our efforts to get it done! #NewPI @Momademia