John Hogenesch

The Quest by Circadian Medicine to Make the Most of Our Body Clocks - The New York Times nytimes.com/2022/07/06/mag…

From the Archives: Santa Ono had thousands of followers. Now, it's hard to find any. chroni.cl/4sLB3ZZ

To honor Dr. Jeff Robbins' legacy, the North American Section of the International Society for Heart Research has established the Jeff Robbins Collaborative Science Award. We invite you to help continue Jeff’s legacy by supporting this initiative. ishrnorthamerican.org/sponsor-a-meet…

@ekinciio @andrewchen Ding, ding ding. 🛎️

@jbhclock @andrewchen How does it feel? Bet your laptop fan just went quiet for the first time in months 😂

the magic of cowork and openclaw and other AI products is that they replace our giant row of infinite browser tabs And lol - no, don't feel guilty, I have too many tabs too. AI makes it so that every workflow that required 4 browser tabs and a spreadsheet is getting collapsed into one AI-native experience Just as one quick example- think about how you used to research a person or a company: LinkedIn tab, X tab, Google tab, notes doc, slack open. now one prompt does it in 10 seconds. the "tab count" of a workflow is basically a proxy for how much AI can compress it if your product eliminates 6 tabs and a copy-paste loop, users will like it. If you can create a whole series of these workflows then your users will absolutely love it. Thus the biggest opportunities are workflows where people currently alt-tab 20+ times per task. Sales, recruiting, research, compliance, procurement. Boring? yes. Massive? also yes. But this is why these agentic tools are going to crush AI doesn't need to be superintelligent to be wildly useful. it just needs to be good enough to close the tabs

@ekinciio @andrewchen Just closed at least 30.

@andrewchen 💯 The browser tab was our generation's filing cabinet. We kept 30 tabs open not because we needed them, but because we were scared to lose context. AI doesn't just close tabs - it eliminates the anxiety of forgetting where you left off. My brain feels lighter because of it.

Does it matter whether oral contraceptives are taken in the morning or at night? We combine circadian hormone modeling with PK/PD models to show that daytime dosing may align better with hormonal rhythms than nighttime dosing. doi.org/10.1371/journa…

kallisto sped up RNA-seq quantification by 50x. Now another 50x speedup... quantify hundreds of millions of reads in a few seconds. This seems too good to be true. But it's true! Incredible accomplishment by @pmelsted.

@RobertStock6 @sinabooeshaghi Amazing.

I’m a baseball player. I’ve never written a single line of code in my life. But over the last few months, I used AI to build a pitching analytics platform from scratch. 8.9M pitches. Custom ML models. Total transparency. Here is a look at what happens when you give an interested athlete access to AI:

A new heart valve stent can expand on its own, offering the potential to keep up with the rapidly growing hearts of babies and toddlers with relevant congenital conditions. Learn more in @ScienceAdvances: scim.ag/4akpzq0

Can confirm. Terrific mentor, colleague, scientist, and friend.

Twitter folks: you may know my friend @LabWaggoner as the best source of science content on this hellscape. BUT: join me in congratulating him for being recognized with the @CincyChildrens @CincyResearch Outstanding Mentorship Award!

That smile you make when you’re Florida born and Gator raised 🧡💙🐊 Game day vibes 🏀

A simple message with big meaning: "I am somebody." We are grateful to Rev. Jesse Jackson for helping teach generations of children to believe in themselves and in one another. Thank you for being part of our neighborhood. 💛💚

Chapter 39 in SLEEP AND HEALTH is focused on "Sleep and mental Health in Children and Adolescents." Led by Michelle Short, Kate Bartel and Mary Carskadon, this chapter outlines how sleep and circadian health play important roles in pediatric mental health concerns. This is especially important as mental health issues in these populations are increasingly causing significant consequences for society. And sleep may be an important way to help! Read more: sleephealthresearch.com/book_sleepheal…

@historyrock_ Wow. That’s what we felt.

imagine how people felt listening to this for the the first time in 1982

@arjunrajlab Why loss? With AI, you're 10x better/faster than before. You know what to do and where to go next. As always, those are the important things.

Ran an AI coding workshop with the lab. There was a palpable sense of sadness realizing that skills some of us have spent our lives developing (myself included) are a lot less important now. I see the future 100%, but I do think it's important to acknowledge this sense of loss.

@HarvardBiz It’s -12°F outside. Definitely Caribbean vacation time.

You don’t need a Caribbean vacation to recharge. A single day can produce benefits, too. s.hbr.org/2YMlPIj

@metapredict @VintageRockN_85 Ramblin’ man, Midnight Rider, and Whipping Post are some of their best.

@jbhclock @VintageRockN_85 will check them out!

Steely Dan or The Allman Brothers?

@metapredict @VintageRockN_85 Jamie, I’m from Florida, so Allman brothers gotta get their due. Amazing musicians all!

@jbhclock @VintageRockN_85 Steely Dan man!

@VintageRockN_85 Peace train.

Share your favorite Cat Steven’s song!