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Delighted to share the publication of the #EDICA study in @JCardFail
doi.org/10.1016/j.card…
In patients 🏥 with acute HF, a natriuresis/diuresis-guided decongestion strategy (@escardio guidelines) vs a weight-guided one showed:
✅ Greater 5-day NT-proBNP reduction
🟰 5-day clinical decongestion
🟰 Length of stay & 30-day outcomes (🏥/☠️)
🟰 Safety & feasibility
🔎 Trend toward not sustained ⬆️ 24–48 h diuresis, weight loss, & loop-diuretic dose
Some conclussions:
1️⃣ Time matters: earlier identification of diuretic resistance improves biomarker decongestion
2️⃣ Yet this did not translate into better short-term clinical outcomes
🎯Still need to close the gap between decongestion and clinical outcomes:
Timing of assessment? Faster titration? Earlier combination diuretic therapy?
Thanks to the great collab of Cardiology - Internal Medicine - Emergency Dep
@MartaCoboMarcos @JanBiegus @esthermonteroh @fernidom @DeCastro9 @dr_pavia @segoviajavierve @ICardiacaSEC @secardiologia @CardioRenalSEC @HospiPtaHierro @Sociedad_SEMI @IcyfaSemi @SEMES_
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