Jenelys Ruiz Ortiz, PhD

SOY DOCTORA!!!!!

SOUND ON. You’re hearing the first howl of a dire wolf in over 10,000 years. Meet Romulus and Remus—the world’s first de-extinct animals, born on October 1, 2024. The dire wolf has been extinct for over 10,000 years. These two wolves were brought back from extinction using genetic edits derived from a complete dire wolf genome, meticulously reconstructed by Colossal from ancient DNA found in fossils dating back 11,500 and 72,000 years. This moment marks not only a milestone for us as a company but also a leap forward for science, conservation, and humanity. From the beginning, our goal has been clear: “To revolutionize history and be the first company to use CRISPR technology successfully in the de-extinction of previously lost species.” By achieving this, we continue to push forward our broader mission on—accepting humanity’s duty to restore Earth to a healthier state. But this isn’t just our moment—it’s one for science, our planet, and humankind. All of which we love and are passionate about. Now, close your eyes and listen to that howl once more. Think about what this means for all of us.

Scientists have created the first map of mitochondria throughout the entire brain go.nature.com/4j6SNKl

🚨IT'S HAPPENING🚨 a woman who cannot speak now speaks through her brain, in real time, with her own voice. no typing, delay, or sounds made. just neural intent to streaming speech this isn’t prediction. it’s embodiment 1/

Loyal’s drug for senior dog lifespan extension drug LOY-002 has completed its FDA efficacy package (RXE) We are on track to hopefully bring the first longevity drug to market *this year* Thanks @lisabonos + @washingtonpost for the exclusive

Huge cancer breakthrough! mRNA vaccine (similar to COVID vaccine tech) shows stunning results against pancreatic cancer! 75% of responsive patients STILL cancer-free at 3 yr, normally 80% recur. Could revolutionize treatment for one of deadliest cancers! Funded in part by @NIH

What gets erased when you integrate single cell data, and can you recover it? Finally, we know what happens and how to recover the lost signals. So excited to share CellANOVA, published online today in NBT! go.nature.com/4hZnzW5

This is not a drill, a mummified #sabretooth cat has been published from the #Pleistocene permafrost of Russia. It's a Homotherium cub! The team (Lopatin et al.) reckon it's Homotherium latidens. Paper is OA: nature.com/articles/s4159… ... cont...

How about a #woollychaferbeetle to brighten up your Monday? #entomemeology #entomologymemes #entomology #woollychaferbeetle #sparrmannia #sparrmanniaflava

This is the foot of a chicken embryo after 12 days of development, captured with light sheet microscopy. You can see scutate scales on the top of the foot and reticulate scales on the bottom 🔬🐥

Thanks for the feature @RockefellerUniv, proud to work at the BRC 🤗🇵🇷👩‍💻

A vertebrate and an invertebrate. 500+ millions of years of evolutionary distance.

The human heart shows signs of ageing after just a month in space go.nature.com/4djwQEA

Superb preprint by Emily Isko @ArkarupBanerjee @TonyZador on the Alston’s singing mouse & the evolution of enhanced cortical control over vocalizations: selective expansion of cortical projections can lead to behavioral divergence over short evo timescales biorxiv.org/content/10.110…

Knocking out using CRISPR TP53 and all its 29 retrogene copies in the fibroblasts of Asian elephants to see which ones are contributing to the cancer resistance and longevity. From George Church's lab. Karpinski et al. bioRxiv biorxiv.org/content/10.110…

The anti-aging impact of metformin (randomly assigned, with controls) in male monkeys after 40 months of treatment, a pan-omic clock assessment —~6 year regression of brain aging, with prevention of atrophy and enhanced cognitive ability —minimal effect on blood sugar —evidence for multi-organ decelerated aging cell.com/cell/abstract/… @CellCellPress

a new version of our preprint on cephalopod sex determination has just been released. lots of new results in here that bolster our original discovery biorxiv.org/content/10.110…

Followers in cancer research: I'm teaching a graduate level cancer biology course spring semester. Does anyone have any textbooks that they particularly like? Something easy to follow that really emphasizes the experimental/ research methods? Help and RTs would be appreciated

Amazing discovery on the evolution of human pigmentation by retrotransposons! Turns out TEs not only helped us get rid of our tails (see 1st comment) but also adapt to different levels of sunlight exposure . #citeas" target="_blank" rel="nofollow noopener">nature.com/articles/s4158…😎

GWAS of unexplained recurrent pregnancy loss in 1,728 cases and 24,315 female controls of Japanese ancestry. In addition to MHC locus, the authors find a rare CNV deleting CDH11 (cadherin 11) increases the risk of pregnancy loss by >3-fold compared to non-carriers. Sonehara, Yano, et al. Nat Comm nature.com/articles/s4146…

@MattMoss5595 so, like, me but as a wife

The future Dr. Ruiz Ortiz (but as my wife)