Jorge Martínez-Cano, PhD

From earlier this week: Newborns’ immune systems are uniquely primed to tolerate harmless antigens doi.org/10.1172/JCI200… Here, Tiffany C. Scharschmidt & team @UCSF report on the early life window for immune tolerance using human samples, finding naïve CD4+ T cells in cord blood have distinct metabolic traits that enable their regulatory potential. The schematic shows mass cytometry metabolic markers in their corresponding pathways. #ImmuneTolerance #ImmuneDevelopment

Whole-body molecular and cellular mapping of the laboratory mouse Biology is usually measured organ by organ. Clevenger et al make the mouse measurable as a whole-body molecular system. Just don’t call it mouse carpaccio. cell.com/cell/fulltext/…

CD4 T cell therapy counteracts inflammaging and senescence by preserving gut barrier integrity | Science Immunology science.org/doi/10.1126/sc…

‘Forever chemicals' may be linked to childhood leukemia. @UCIrvine-led study scientists alongside Dr. Veronica Vieira found that exposure to previously unknown PFAS chemicals was associated with a higher risk of acute lymphoblastic #leukemia. 📰 bit.ly/4cSlWaP

Nature research paper: Early fibrotic niches establish tumour-permissive microenvironments go.nature.com/4eyjatK

La mosca del vinagre ayuda a entender cómo una misma proteína puede frenar o favorecer el cáncer. El estudio liderado por Carlos Estella y Antonio Baonza revela cómo distintas versiones de p53 actúan de forma diferente en las células. @CSIC @UAM_Madrid cbm.uam.es/index.php/2026…

Was a pleasure to present the EpiFlow platform at #EMBOBrainEpi, great meeting! Congrats to the organizers and @EMBO #EpiFlow #Neuroepigenetics #epigentics #singlecell #flowcitometry

DNA methylation-based classification of hematolymphoid neoplasms ashpublications.org/bloodadvances/… @anusaksena congrats on this work!

Multiomics immune profiling of a patient-relevant orthotopic lung cancer model using SEPARATE-Seq nature.com/articles/s4146… @NatureComms 🇧🇪

After a long long long way! Jorge es un crack!! Take a look at my article! link.springer.com/10.1007/s12035… #FriedreichAtaxia #Neurons

La investigadora Ana Cvejic, del Biotech Research & Innovation Centre, ha visitado el CBM para impartir un seminario sobre la identidad de las células madre hematopoyéticas. En él, analizó cómo se remodela esta identidad tanto en el desarrollo biológico como en enfermedad.

Co-occurring mutations make better biomarkers to predict therapy response. Need better models to capture these associations with co-mutations. Foundation models can do this @TreyIdeker #AACR26 @AACR

@FreyramF @jmarcan93 Paqui! qué ilusión! muchas gracias :) espero que estéis todos muy bien por el CABD. Un abrazo!!

@jmartcan @jmarcan93 Me alegro mucho! Te deseo muchos éxitos

With mixed emotions, it's about time to close chapters and begin new adventures.

@ToribioLab thank you, guys 🥰 I'm going to miss you all!

@jmartcan Best of luck, Jorge! 😘

I'm very excited to announce that the Jo Lab is hiring our FIRST EVER PhD candidate! f you're eager to drive discovery in plants, join us at UU Plants! More info: uu.nl/en/organisatio… Lab website: thejolab.org #Plantbiology #Phd #Job

@harry_brennan Wow! Way to go, Jesús :) That’s super Interesting; I wish I could attend, I’m learning a lot about spatial transcriptomics here in Berlin. Any idea if the talk will be recorded and accessible for non attendees somehow ?!

🧠Honored to take part in “Seeing Biology in Space: Integrating Spatial Transcriptomic and Multiomic Data to Dissect Brain Function” on April 21, 2026, at the Cajal Neuroscience Center (CNC‑CSIC), Alcalá de Henares, Madrid. See you at 12 h! 🔬bonsailab.com/seeing-biology…

The contribution of 9p deletion in B cell acute lymphoblastic #leukemia (#B-ALL) has remained elusive since its discovery more than 40 years ago. doi.org/10.1172/jci.in… Here, Isidro Sánchez-García, @jmartcan @KimNich83859256 & team @CBM_CSIC_UAM combined genomic analyses and functional models to show that the co-deletion of two contiguous genes, Pax5 and Cd72, drives oncogenesis in mouse models. The image shows splenic H&E staining from the Cd72+/–;Pax5+/– (A120) leukemic mouse with infiltration of blast cells and loss of architecture.