

John Lees
280 posts

@johnlees6
Pathogen informatics and modelling https://t.co/2Qg0pvaFg3 (Research group leader at EMBL-EBI - https://t.co/lJdwj0idt0)



Are you a student in France studying computer science, statistics, or bioinformatics? @FranceintheUK has opened a new round of internships hosted at EMBL-EBI. Find out more and apply. ebi.ac.uk/about/jobs/int…




A cool upcoming feature: When you upload a sample to Solu Platform, we’ll search all public NCBI samples for related genomes. This is built on the awesome AllTheBacteria database by Martin Hunt, Leandro Lima, @shenwei356, @johnlees6 & @ZaminIqbal

Why do #bacterial species' #TransformationRates vary so dramatically? @epcrocha @labXC &co show that #Legionella & #Acinetobacter transformation rates evolve by sudden changes, likely caused by conflicts between #MGEs and the host bacterium #PLOSBiology plos.io/4dMviTR

First paper from my student Daria Frolova's PhD now on biorxiv: biorxiv.org/content/10.110… The key question: plasmids change structurally ~as fast as they mutate, so how can we decide whether 2 plasmids are "the same plasmid" for epi purposes? 1/n

Rapid species-level metagenome profiling and containment estimation with sylph go.nature.com/3BBVqDC


We are happy to have been selected by SMBE to host a satellite meeting on Pathogen Pangenome Evolution Between and Within their Hosts: smbepangenomes.bacpop.org We are expecting the meeting to be in Tokyo on 26-28th November 2024, save the date!

Sam has then wrapped it all up in a nice snakemake pipeline CELEBRIMBOR (Core ELEment Bias Removal In Metagenome Binned ORthologs) which lets you go from MAGs to pangenome github.com/bacpop/CELEBRI…








