
Principles of CRISPR-Cas13 mismatch intolerance enable selective silencing of point-mutated oncogenic RNA with single-base precision | @Farehlab | Science Advances science.org/doi/10.1126/sc…
English
Johnson Mak
407 posts

@johnsonmak
Virologist, @GlycoGriffith, @johnsonmak.bsky.social, molecular virology, cell biology, and biophysical tools. Co-Editor-in-Chief for Retrovirology




Our new preprint is out: we solved the structures of HIV-1 matrix (MA) from intact virions by SPA. The structure led us to a surprising discovery resolving a long mystery in HIV-1 biology – peptide SP2 regulates the maturation of the HIV-1 matrix. 🧵1/x tinyurl.com/c7szhtfa





We are delighted to share that AHRI director for basic & translational science Prof @Thumbi_Ndungu has been elected as a member of @theNAMedicine Election is one of the highest honours in the fields of health & medicine. 🎉 Congrats, Thumbi! More ➡️ ahri.org/prof-thumbi-nd…












