Look forward to seeing everyone in a few hrs, ASH workshop on functional precision medicine #ASH2025 @ASH_hematology @StJudeResearch @StJude
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Jun Yang
568 posts
Jun Yang
@Junjyang
Pharmacologist and geneticist through and through
Tennessee, USA Katılım Ekim 2009
590 Takip Edilen921 Takipçiler
Jun Yang retweetledi
This is HUGE!
No embargo needed for @AACR publications deposited in PubMed Central - enabling compliance with the NIH public access policy without spending exorbitant open access fees.
Elizabeth McKenna@ElizSMcKenna
You can read the AACR journals' policy here: #funder" target="_blank" rel="nofollow noopener">aacrjournals.org/pages/open-acc…
"The Author Accepted Manuscript is permitted to be deposited in PMC and made available to the public on or after the first online publication date of the Version of Record." English
New paper alert! Our team published in @NatureComms
on MeiHMM - a hidden Markov model that identifies meiotic nondisjunction error types in chromosomal abnormalities, like Down Syndrome, without parental data! #ComputationalBiology @StJudeResearch
doi.org/10.1038/s41467…
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Kudos to @maud_maillard on her new paper in @jclinicalinvest! Our findings indicate NUDT5 is a key regulator of thiopurine metabolism, offering new insights into how cells strike the balance between de novo vs salvage purine synthesis.
Journal of Clinical Investigation@jclinicalinvest
Thiopurines for the treatment of cancer or autoimmune disease are limited by their toxicity. @MaudMaillard @Junjyang @StJudeResearch identify germline NUDT5 variants that affect thiopurine metabolism and cytotoxicity in children with ALL, having implications for individualized thiopurine therapy. jci.org/articles/view/…
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@LBastian_MD @BloodPortfolio Thanks for writing the editorial piece! A lot more to learn about this drug!@StJudeResearch @StJude
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What determines Inotuzumab sensitivity in #ALL?
New @BloodPortfolio study from C. Escherich & @Junjyang Lab highlights the role of B cell developmental state and EBF1. It was a pleasure to provide a commentary!
🔬 doi.org/10.1182/blood.…
🗒️ doi.org/10.1182/blood.…
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One of my favorite meetings!
ESH (Haematology)@ESHaematology
We are a go! #ESHALL2025 started this morning! We are happy to welcome participants in Malahide for the 2,5-day ESH 4th Translational Research Conference on ALL More information➡ bit.ly/4cy9jAS Chairs: @kathrinbernt @CoolsJn @DombretHerve @ullawk #ESHCONFERENCES #LEUsm
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Beyond proud to be a part of this incredible group, and so grateful to my lab members, @StJudeResearch, @MolOnc_StJude and my network of close collaborators and friends, including (among many) @JunQiLab and @TheAbraLab. Looking forward to to #aacr25!
aacr.org/meeting/aacr-a…
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Jun Yang retweetledi
Instead of listing my publications, as the year draws to an end, I want to put pressure on the commonplace assumption that productivity must always increase. Good research is disruptive and thinking time is central to high quality scholarship and necessary for disruptive research
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Excited to share our latest work in @NatureCancer to get a better understanding why relapsed T-ALL is so deadly and potential target strategies, led by Jason Xu and @changya1 with members of David Teachey, @junjyang, @CMullighan and many great colleagues. twtr.to/foS9o.
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Why is #ALL highly curable in #kids but carries a much worse prognosis in #adults?? Check out our new paper @JCO_ASCO describing genomics of age-related differences in ALL drug sensitivity @StJudeResearch @MDAndersonNews @UChicagoLeuk @NitinJainMD
St. Jude Research@StJudeResearch
Researchers identified distinct molecular subtypes of B-ALL that occur in different age groups explaining why cure rates vary between children and adults. The study suggests treatments should be tailored based on underlying molecular groups beyond age. ow.ly/k2SL50SSlU2
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@Richardson_S_E Congrats! Thanks for stopping by Carolin’s poster last nite.
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@AdeleKFielding @hermione_allen @EHA_Hematology I stopped by your posters last nite, beautiful work!
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In beautiful #Madrid for #EHA2024 @EHA_Hematology rooting for Carolin and her poster presentation re inotuzumab resistance in B-ALL
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@NitinJainMD @mkonople @EHA_Hematology Thank you @NitinJainMD for picking the nice location and food! #granvia #Madrid
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Had an amazing dinner discussion with the two most wonderful people I know
Marina Konopleva (@mkonople) and Jun Yang (@Junjyang)
@EHA_Hematology
#EHA2024
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Excited to share a recent publication in Nature Communications from our great team of investigators where we reveal a previously unknown secondary mechanism of action of the triazole antifungals against Aspergillus fumigatus mediated by Hmg1
nature.com/articles/s4146…
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Excited to share the first spatially resolved multiomics atlas for human bone marrow, published today in @CellCellPress. twtr.to/cJ099. Wonderful collaborations with Ling Qin @LingQin6, Charles Nelson, Martin Carroll, Ivan Maillard, Vinohd Pillai @pillai_vinodh labs!
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Memphis, TN 🇺🇸 English
Jun Yang retweetledi
Congratulations to Ching-Hon Pui, MD, for receiving the @AACR-@StBalrdricks Foundation Award for Outstanding Achievement in Pediatric Cancer Research. Your pioneering research is lifesaving, and your commitment is inspiring. ow.ly/EzF250Ra17K
#AACR24
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Memphis, TN 🇺🇸 English
@Junjyang @jiyang_yu @StJudeResearch Congratulations, @Junjyang and team!!! Such exciting and important work!
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The stars are aligning (literally) for our paper to come out today 😂🌞 @jiyang_yu @StJudeResearch
St. Jude Research@StJudeResearch
By characterizing B-cells’ developmental stages, St. Jude scientists designed and tested a drug combination to effectively treat resistant B-cell leukemia and reduce side effects. Learn more about the research by @Jiyang_Yu and @JunJYang. bit.ly/4avBOh1
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