@TimofejM77894 Yes! I am currently following up on this work to evaluate by which autoantibody is the one causing the disease and through which mechanism is it happening
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keyla sá
131 posts
keyla sá
@keylas3
Studying how autoantibodies drive neurological disease. Autoantibodies • Neuroimmunology
New Haven, CT Katılım Ocak 2012
249 Takip Edilen359 Takipçiler
Excited to share our study in Cell!
Using passive transfer experiments, we found that autoantibodies from Long COVID patients can induce neurological and pain-related phenotypes in mice, supporting a causal role in disease.
cell.com/cell/abstract/…
#LongCOVID #Autoimmunity
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keyla sá retweetledi
New talks from this year's International #MECFS Conference are online!
📌 "Autoantibodies analysis in Long COVID and ME/CFS" - @keylas3
📌 "Effects of Autoantibodies on Neuronal Function" - Marlen Alisch
📌 "Bio-SEG PEM study" - @chris_puta
🔗 t.ly/of9LS
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I'm excited to share that our recent paper has been featured in Nature Reviews Neurology.
Our study provides evidence that autoantibodies can play a causal role in the neurological manifestations of #LongCOVID.
nature.com/articles/s4158…
#Autoimmunity #Neuroimmunology #Immunology
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This vídeo highlights my scientific journey and my research demonstrating a causal role for autoantibodies in #longcovid #science #autoimmune #scienceexplained
youtu.be/RcWh-VzALpo?fe…
YouTube
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I’m honored to be featured in a Yale News article discussing our work showing that autoantibodies from #LongCOVID patients can induce neurological phenotypes in mice, providing evidence for a causal role in disease.
Read: news.yale.edu/2026/05/28/y...
#Autoimmunity #Neuroimmunology
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@PatientPersists @PutrinoLab Hi Siebe, yes, the analysis was also performed blinded. You can find this in Figure S8E, and we also mention it in the Results section.
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Hi Akiko @PutrinoLab
Can you clarify whether the behavioral experiments were blinded to whether mice were treated or in control group? The methods don't state this. We know that experimenter expectations can bias results
Prof. Akiko Iwasaki@VirusesImmunity
Excited to share our study by @keylas3 et al. on pathological autoantibodies in people with Long COVID. We asked whether IgG in patients with Long COVID bind to human tissues/antigens and cause pathologies when transferred into mice. With @PutrinoLab doi.org/10.1016/j.cell…
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keyla sá retweetledi
Important #LongCovid finding of auto-antibodies in patients directed to neural tissue, and then, by transferring the antibodies, recapitulated the disease symptoms in mice @CellCellPress @VirusesImmunity @putrinolab
cell.com/cell/abstract/…
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keyla sá retweetledi
Excited to share our study by @keylas3 et al. on pathological autoantibodies in people with Long COVID. We asked whether IgG in patients with Long COVID bind to human tissues/antigens and cause pathologies when transferred into mice. With @PutrinoLab
doi.org/10.1016/j.cell…
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keyla sá retweetledi
So grateful for this @ScienceMagazine piece by @jcouzin highlighting 2 studies - @DrDenDunnen's and our's by @keylas3 et al (with @PutrinoLab) showing that IgG from people with #longCOVID can transfer patients' symptoms in mice👇🏽
science.org/content/articl…
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@VirusesImmunity @keylas3 @SilvaJ_C @PutrinoLab Every so often, there's a study that just knocks me flat for its scientific mastery, and this is one such. Congratulations to all involved.
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keyla sá retweetledi
Sharing our new study by @keylas3, @SilvaJ_C, Rafael Bayarri Olmos et al (with T. Horvath & @PutrinoLab) showing that a passive transfer of IgG from patients with #longCOVID into mice recapitulates ⬆️ pain and other symptoms 🧵 (1/)
medrxiv.org/content/10.110…
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keyla sá retweetledi
Excited to have this amazing new #longcovid work out in the world thanks to an always amazing team and with continued gratitude for our collaboration with @VirusesImmunity 👯♀️
Please check out Akiko’s comprehensive tweetorial on the preprint, and I’ll add just a few comments. 1/
Prof. Akiko Iwasaki@VirusesImmunity
Sharing our new study by @keylas3, @SilvaJ_C, Rafael Bayarri Olmos et al (with T. Horvath & @PutrinoLab) showing that a passive transfer of IgG from patients with #longCOVID into mice recapitulates ⬆️ pain and other symptoms 🧵 (1/) medrxiv.org/content/10.110…
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keyla sá retweetledi
From a @PlzSolveCFS presentation, @PutrinoLab discusses an unpublished finding from @keylas3 and @VirusesImmunity: mice some exhibit balance and sensory issues (sounds like POTS and SFN?) after being injected with IgG from human Long Covid patients youtu.be/F3Sv9tfu_ww?si…
YouTube
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Another cool thing: our findings seem to have been independently validated by the @PutrinoLab, who recently showed similar preliminary data on this scientific conference (May 2024): youtube.com/watch?v=F3Sv9t… 10/11
YouTube
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A strong indication for #autoimmunity in #longcovid: transfer of antibodies of patients induces symptoms in mice. Check out our latest preprint @biorxivpreprint: biorxiv.org/content/10.110… 1/11
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keyla sá retweetledi
Essa pergunta embora pareça simples e fácil de responder ao aluno com um conjunto de “dedique-se, passe nas matérias, aprenda inglês, faça IC”; não é simples assim. Há inúmeras pedras no caminho que podem facilmente impedir o sucesso de pessoas capazes.
cienciaquenosfazemos.org/post/por-onde-…
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keyla sá retweetledi
Brasileiro é swingueiro, é coração
A gente é que bota fé na vida pode crê
Tamo ai para viver para encarar.
Se você quiser colar com a gente, não tem nada, não.
🇧🇷 o povo de mistura, é raça, é pé no chão.
Objetividade na vontade de crescer. @HHMINEWS @hernandezmsilva #FHScholars
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