Katie Guzzetta 🌻

Weekend read! Microbiota extends reproductive lifespan Germ-free female mice undergo accelerated primordial follicle loss & reduced reproductive capacity that are restored upon post-natal colonization. Microbial SCFAs & fiber mitigates ovarian dysfunction cell.com/cell-host-micr…

#Microbiota from young mice restore the function of aged ISCs. @GutMicrobiome #aging sciencedirect.com/science/articl…

#GutMicrobiota transfer from old mice accelerates aging in adults sciencedirect.com/science/articl…

Excited to share a new #Commentary by Marco Ventura, a leading figure in the field of #Bifidobacterium research: “Mapping the #genomic landscape of two key human #gutmicrobial species: Bifidobacterium infantis and Bifidobacterium longum” Read👉oaepublish.com/articles/mrr.2… #Microbiome

Adolescent obesity induces sex-specific alterations of action control nature.com/articles/s4138…

We analyzed 2.6M food & beverage logs from ~20,000 people to uncover (among other insights) what’s consumed every 2 hours across a 24h day. Some usual suspects… and a few surprises. Take a guess—then check the list 👇 nature.com/articles/s4225… @NatMetabolism

Not just passengers! Perspective by Colin Hill & Co examines role of phages in fecal microbiota transplants (FMTs). Phages may actively reshape the recipient’s gut by transferring genes between microbes, potentially influencing treatment success cell.com/cell-host-micr…

@svetlana_up It will be held only in person with a strong emphasis on networking and interactions 🙂

@ktguzz Great! Is the event hybrid or onsite only?

Two more days until the 2nd edition of our Swiss-wide #microbiome & health event! 🇨🇭🦠 We've got a brilliant lineup of speakers and I'm excited to once again moderate the panel discussion. Make sure to register for free at foodhealth.ch/en/agenda

Feeding gut microbes to nourish the brain: unravelling the diet–microbiota–gut–brain axis @NatMetabolism @E_MSchneider @jfcryan nature.com/articles/s4225…

Our new preprint by @peowenlu @SaefIzzy @weinerlabhms and colleagues shows that nasal anti-CD3 monoclonal antibody treatment can reduce neuroinflammation in a mouse model of Long COVID, even when administered at 4 weeks after infection 🧠 biorxiv.org/content/10.648…

New online! The microbiome regulates host metabolic health and diseases through microbial enzymes dlvr.it/TRwk2W

@simyersin Congratulations to @simyersin and team for their newest publication! "Strain-level translocation and enrichment dynamics of oral #bacteria in the lower gastrointestinal tract of stunted children" tandfonline.com/doi/full/10.10…

If people with #celiacdisease lack the microbes needed to break down certain fibers, they don't benefit from consuming them @VerduLab, @AlbertoCaminer7 & colleagues found patients with #celiacdisease had impaired microbial fiber metabolism in the small intestine, which was associated with depletion of the fiber-degrading taxa: ✅ Findings align with @DrHArmstrong research on β-fructan fibers' role in inducing inflammation if the microbes needed to ferment the fiber are not present ✅ While a high fiber intake is often recommended to newly diagnosed patients with celiac disease alongside the gluten-free diet to improve constipation, these findings suggest that it's first important to restore the gut ecosystem ✅ In mice, an inulin-supplemented diet increased small intestinal short-chain fatty acids and could be used as adjuvant therapy for the gluten-free diet to promote mucosal healing, when metabolizing taxa are present 📚 Read more: nature.com/articles/s4146…

New! Online now: The gut microbiota alleviates depression by remodeling gut-brain energy metabolism dlvr.it/TRp62v

Our new study @NatureMedicine from the Human Phenotype Project: Analyzing diet and microbiome data from 10,000+ people, we found that what you eat is strongly linked to which microbes live in your gut, down to specific foods like coffee, yogurt, and milk driving distinct microbial signatures. We also simulate personalized dietary interventions with predicted microbiome shift effects that are associated with improvements in cardiometabolic health Read here: nature.com/articles/s4159… HPP: humanphenotypeproject.org/home

What if a simple blood test could help detect early cognitive decline? Our latest study shows that microbe-derived metabolites shaped by the gut microbiome can distinguish early-stage cognitive impairment with promising accuracy. tandfonline.com/doi/full/10.10…

More today on exercising fathers and metabolic health of offspring, summarized nature.com/articles/s4158…

Happy to share our latest study about global patterns of soil microbial nitrogen and phosphorus use efficiency, just published in Nat. Commun.🎉🎉. Thanks for all co-authors' contributions (Decai, @mrillig, @ykuzyakov, @ManuDelBaq, @JosepPenuelas et al.) nature.com/articles/s4146…

This study identifies gut-derived IL-17A–STAT3/RORγt signaling as a mechanistic bridge between sleep deprivation and neuroinflammation, providing direct evidence for the immunological basis of circadian rhythm-related depression. sciencedirect.com/science/articl…