It was a great pleasure to work with you @Hongtao_Liu2019 !! We wish you all the best in this new stage of your career at the Hangzhou Institute of Medicine, Chinese Academy of Sciences !
#membrane #transporters #structures
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Locher Lab
106 posts
Locher Lab
@lab_locher
Structural Biology of Membrane Proteins - ETH Zurich | Tweets by lab members
Zurich, Switzerland Katılım Temmuz 2019
133 Takip Edilen1.8K Takipçiler
We are excited to share that @Lorenzo_Rossi_H won the poster prize at @SFGlycobiology Annual Meeting two weeks ago! Well deserved!
#glycotime
#proudlabmembers
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We say goodbye to @KNosol who is embarking on the next stage of his scientific career. We wish you all the best!
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Thank you @a_s_ramirez for being a great colleague, fantastic researcher and mindfulness coach. We will miss you so much! Best of luck in the US!
#glycotime #we_are_sad
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Congratulations to our fantastic @a_s_ramirez and Ben Lampson for their great work on OST and its inhibition now out in @CellCellPress !! It was a fruitful collaboration with @kaelin_lab and Contessa Lab.
#glycotime #CRISPR #cryoEM
Check it out:
cell.com/cell/fulltext/…
GIF
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We have exciting news on NTCP! In our very recent study - now out in @NatureComms - we found out how NTCP interacts with the antiviral drug bulevirtide.
Congratulations to @Hongtao_Liu2019 and the rest of the team #SLC #CryoEM
Find out more here: rdcu.be/dBT8p
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Very happy to have a visit from our alumni, especially when they bring #PrixSchläfli 🤩🤩
Congrats @Joel_S_Bloch !
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Great to see NabFab in use!👏
Andreas Boland@BolandLab_GE
📢Preprint Alarm🚨 biorxiv.org/content/10.110… In a first collaboration with the Stoeber lab @MiriamStoeber we characterise an extracellular nanobody (NbE) that binds as an antagonists to the µ-opioid receptor. This work was driven by Jun Yu @JunYu_unige and Amit Kumar🌟🌟
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@chancie_t @NatureComms Thanks! The NBD1 has a significantly lower resolution than NBD2 due to its high conformational flexibility. This flexibility has also been reported for other ABC transporters with a degenerate ATPase site, e.g. MRP4
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@lab_locher @NatureComms Excellent work! Just out of curiosity, do you have an explanation why NBD1 in your wild-type structure is not resolved at all?
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We are very happy to share with you that our BSEP (ABCB11) paper is out in @NatureComms ! Find out about the mechanism of bile salt extrusion and BSEP inhibition here : nature.com/articles/s4146…
#ABCtransporters #cryoEM
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Locher Lab retweetledi
📢We are recruiting! Please RT! A 4-years #postdoc position is opened in the Wild Team at @IBS_Grenoble. #cryoEM #glycotime. More information here: tinyurl.com/2ezztekd
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Congratulations to @AncaCiuta for winning the poster prize at the @RESOLUTE_IMI conference!! 🙌
#transporters #SLC #CryoEM
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Congrats to @AncaCiuta, @KNosol, @juliakkowal, our collaborator Somnath Murkherjee from Kossiakoff Lab, and everyone part of the project!!
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We are excited to share our latest publication on the human liver drug importers OATP1B1 and OATP1B3 in functionally distinct states, now available in @NatureComms
Read more about the novel bicarbonate binding site here: nature.com/articles/s4146…
#SLCtransporters #cryoEM
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ABCG2 meets nanobodies! Check out our new publication on ABCG2 inhibition: sciencedirect.com/science/articl…
#ABCtransporters #ABCG2 #nanobodies #cryoEM
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Congratulations to @KNosol for being awarded an @ETH medal for an outstanding doctoral thesis!
#ABCtransporters
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Check out our recent review on the N-glycosylation by @a_s_ramirez, and get a great overview of the structural and functional studies performed on the pathway as well as recent advances. Available here:
academic.oup.com/glycob/advance…
#glycotime
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SCNAT@scnatCH
🥂#PrixSchläfli 2023 award for the four best #dissertations in natural sciences: Simone Bavera (Astronomy), Joël Bloch (Biology), Michelle Frei (Chemistry) and Ariadni Afroditi Georgatou (Geosciences). Congratulations!!!! ➜scnat.ch/en/id/QnAEd @unige_en @ETH @EPFL @snsf_ch @CH_universities
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