luke bateman

@INVESTMENTSHULK can we talk about the precision on the approach here??

I KNOW NOT WITH WHAT WEAPONS WORLD WAR III WILL BE FOUGHT, BUT WORLD WAR IV WILL BE FOUGHT WITH STICKS ON DRONES.

When you check on your Claude Code to see how hard it's cooking and it's just been waiting for you to approve the initial mkdir command.

@PurpyNFL gonna need more info boss

How the Range Rover looks at Tiger after he’s consumed an entire pharmacy of Ambien

Hate to think of how many students have suffered and job applications have been ignored because the software that does stuff like this basically doesn’t work.

just picked up a copy of this and can’t recommend enough

@DocStrangelove2 watching it slowly puff up like the battery in a tesla

I think they may have experienced a baffle strike.

Claude is helping me organize my whole music career and other businesses in days ... and it's moving my business forward at a high rate! Some tech youngbull I met on LinkedIn gave me a incredible template! Who else can help me with Claude

@scaling01 everyone in the comments coping bc they got onshotted

talked to Opus 4.6 for a couple of hours about personal problems and it has this weird response mode where it's very commanding "put the phone down", "close the laptop", "Save this conversation. Set the reminder. Go to sleep.", do this, do that not sure how I feel about it

No Claude, the project will not take me 2-3 months. We will finish it today.

@barbarismcrit @SachaRoytman this reply deserved to be a quote tweet imo

@SachaRoytman Have you tried releasing the hostages?

Shocking footage from this evening of a ballistic missile striking the city of Dimona in southern Israel. Home to 40,000 residents, a direct hit on a civilian neighborhood is a war crime! I’m furious that world leaders still refuse to stand up and call out Iran. When Israel defends itself, every UN body goes crazy — cheered on by hypocritical Western nations.

@lilsketch lobster

gun pointed at yo head, name a rock

@bryan_johnson bro just wanted to flex his base stats pre-nerf i see you @bryan_johnson

Two doses of magic mushrooms degraded my sperm count from the 99.6th percentile to the 77.7th. This may be a first-in-human observation. Context: we ran the most quantified magic mushroom (psilocybin) experiment ever conducted. We were asking if psilocybin is a longevity therapy. After seeing the data, we think it is (see reply post for the experiment summary). Also, like most things biology: the results are complicated. My data suggests that the magic mushrooms (psilocybin) negatively impacted my fertility markers. Before the first psilocybin dose my motile sperm count was at 99.6th percentile for men under 25 years of age, it dropped to 77.7% and partially recovered to 89.3% following the first dose, and second doses, compared to the same age cohort (numbers compare similarly to my age cohort as well). 3 days following my second dose (first dose 25 mg, second dose 28 mg) . Motility: dropped 51% . Total count: almost unchanged, dropped by 2% . Total motile count: dropped 52% . Normal morphology: dropped by 50% 20 days post 2nd dose, the pattern continued, with typical latent effects on total sperm counts Motility: recovered back to -2% of pre-psilocybin baseline: . Total count: dropped by 38%, latent effect. . Total motile count: remained inhibited at -39% of pre-psilocybin baseline, (despite motility normalizing, due to the total count drop) . Morphology normalized to -10% of baseline levels. Reduction in free testosterone might have contributed to the effect. While total serum testosterone increased by 30% 3 days following the 2nd dose (neither FSH or LH were meaningfully affected either), and continued to be at 11% above baseline, SHBG increased by 37%, SHBG binds testosterone and reduces its bioavailability and activity. My free testosterone (direct) showed 24% and 23% drops at 3 and 20 days post 2nd dose. In light of the neuroplastic, well-being, brain reset, and systemic metabolic and anti-inflammatory benefits, the trade-off is probably worth it. Especially considering that the magnitude of inhibition has no meaningful effect on actual fertility (total motile counts above 50 million are still on the safe side). This is a first-in-human observation, to our knowledge there is no published human clinical study demonstrating that psilocybin diminishes male fertility markers. General mechanistic evidence exists for recreational and psychoactive drugs possibly inhibiting fertility markers due to their effects on the hypothalamus-pituitary-adrenal axis and general hormonal reset.  Yet no direct evidence for psilocybin or other similar psychedelics inhibiting fertility markers exist. A potential mechanism for the immediate inhibition of motility could involve direct serotonergic signaling in sperm. Human sperm express multiple serotonin receptors, including 5-HT2A, and one recent study found that a 5-HT2A antagonist reduced sperm motility, suggesting that 5-HT2A may regulate motility. Psilocybin is known to bind 5-HT2A with high affinity.

call me ronald reagan the way i'm boutta airdrop these into san francisco and oneshot an entire generation of seed stage startups

if you’ve ever worn black to a protest, used Signal, or carried a first aid kit, a federal jury just decided that can all be evidence of terrorism. a quick thread on the Prairielands convictions from last week, and what they mean for the right to protest in the US:

@PopBase what happened to paul bettany goddamn

First look at Robert Pattinson as Scytale in ‘Dune: Part Three.’

@cringelemon quote of the year

If you run around with one of these and you're not military or law enforcement, you will be considered a threat.

@AndrewFeinberg oh he’s already touching those kids if that’s what you mean

this account is amazing but it's gonna get pretty dark in a few months.

@Shadzey1 imagine getting barretmogged in person damn

Pulling up with a Barrett is a vibe.

america deindustrialized so extensively, we can’t even manufacture consent anymore

called it