Luke Taplin-McCallum

313 posts

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Luke Taplin-McCallum

Luke Taplin-McCallum

@luketapmc

Adtech, startups, building things.

London Katılım Kasım 2011
122 Takip Edilen168 Takipçiler
Emily
Emily@Emily21409809·
@luketapmc @PokemonStockUK I got an email saying Action Required for your pre order. I tried updating my address and even used different credit and debit cards, it still failed. And every time I tried, it held the amount of my credit card...
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Pokemon Stock Alerts UK
Pokemon Stock Alerts UK@PokemonStockUK·
Reminder that PC are starting to take payment for Ascended heroes booster bundles. Make sure you have enough in your account for it to clear to avoid potential delays.
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Emily
Emily@Emily21409809·
@PokemonStockUK Does anyone have clues on this? I tried different cards, it still failed in proceeding payments, and I have money in my cards. Do I get blocked? It was the same for my previous ETB pre order, I can't get around it...
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Luke Taplin-McCallum
Luke Taplin-McCallum@luketapmc·
@antonioventre I'd challenge this. Creative can account to 50% of a campaign's effectiveness. Yes, strategy, targeting, conversion tactics and how the funnel is stitched. Creative is THE biggest lever we can single handedly control.
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Antonio Ventre
Antonio Ventre@antonioventre·
Hot take: the brands struggling most on Meta right now are the ones who increased creative output when performance dropped. More ads does not fix a strategy problem. If your awareness stage distribution is wrong, 50 new ads targeting the same stage will not help. If your offer is weak, no amount of creative will save it. If your landing page converts at 1%, more traffic just means more wasted spend. Before you produce another batch of creatives, ask yourself: Is the problem the creative, the message, the funnel, or the offer?
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theboganguru
theboganguru@theboganguru·
@morellifit I am getting mixed feed back on if to take them after having skin cancers and a coat on a kidney
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Michael Morelli
Michael Morelli@morellifit·
Peptides don’t give you a “kick.” They heal at the root: • BPC-157 → gut, joints, inflammation • TB-500 → tissue recovery • MOTS-c → mitochondrial function • CJC/Ipamorelin → growth hormone • GHK-Cu → collagen, hair, skin This is what real optimization looks like.
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Luke Taplin-McCallum
Luke Taplin-McCallum@luketapmc·
Glycinate at night is usually the gentlest form and many notice they relax and sleep better, especially if they’re running low from stress, alcohol, or crappy diet. That said, the “most people are deficient” claim is a bit overstated. Subclinical low levels are pretty common (around 40-50% don’t hit the RDA), and studies do show modest improvements in mild anxiety and sleep quality for those who are low. But it’s not a miracle fix for everyone - results vary a lot person to person. Reducing alcohol and processed food plus eating more mineral-rich stuff (leafy greens, nuts, seeds) is honestly the smartest starting point before adding pills. I used to throw magnesium and a bunch of other calming supps (glycine, taurine, theanine, etc.) into my stack thinking more was better, only to realize I was overlapping on the same pathways and not getting extra benefits. That’s why I built Evidose (evidose.app) it collates over 50,000 pieces of published research so you can see what’s actually worth keeping in your stack without the guesswork.
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Gary Brecka
Gary Brecka@thegarybrecka·
If you’re anxious, not sleeping well, or constantly tense… there’s a good chance you’re deficient in magnesium. Magnesium supports over 300 enzymatic reactions: - nervous system regulation - muscle relaxation - sleep quality - blood sugar control Most people are low. Start here: - magnesium glycinate at night - reduce alcohol and processed food - increase mineral intake overall Sometimes the problem isn’t complex. It’s just missing raw materials.
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Luke Taplin-McCallum
Luke Taplin-McCallum@luketapmc·
Magnesium + B6/D is a pretty common starting combo — mag for calm and sleep, D for energy (especially if you don't get much sun), and B6 can help with the mag absorption. I'd start with just those two and see how you feel before adding more. I kept adding random supps and ended up overlapping on a bunch without extra benefit. That's why I made Evidose (evidose.app) to pull from over 50,000 research papers and figure out what's actually worth taking in a stack
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crybaby 𓏵 mrs riley
crybaby 𓏵 mrs riley@liaooww·
what supplements should i buy ????? was thinking of magnesium + vitamin B6/D
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Luke Taplin-McCallum
Luke Taplin-McCallum@luketapmc·
everyone really is different. Magnesium, D3 + K2, and collagen/glycine are solid basics that a lot of people notice help with sleep, energy, and joints. The hard part is knowing what you actually need versus what overlaps and does nothing extra. I used to throw a bunch of stuff in my stack and realize later I was doubling up on similar pathways. That's why - cue ad - I built Evidose (evidose.app) that collates over 50,000 pieces of published research to check full stacks
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Veronica, Collagen Scientist
Veronica, Collagen Scientist@celestialbe1ng·
“What supplements should I take, Veronica??” Short answer: I don’t know. Everyone is a different level of fucked up. But if you held a gun to my head: • magnesium • K2 • D3 • glycine / gelatine / collagen • some form of calcium • mixed tocopherols E (Tocovit or @anabology) • B1 + B complex • orange juice and acerola cherry • liver • oysters • carrot salad, mushrooms, or activated charcoal—whatever agrees with you • human connection • whimsy • aspirin
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Luke Taplin-McCallum
Luke Taplin-McCallum@luketapmc·
Zinc + mag glycinate is a popular combo for a reason — mag helps with sleep and recovery, zinc supports hormones and immunity. A lot of ppl notice better energy and mood when they're actually low in them. Just don't go crazy high on zinc long term (15mg or less is usually plenty). I used to throw random things into my stack and overlap without noticing until I built Evidose (evidose.app) that collates over 50,000 pieces of research to see real interactions
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Cecond_Thoughts
Cecond_Thoughts@cecond_thoughts·
Dunno if it's just placebo, but ever since I added zinc and magnesium glycinate to my supplement stack... 🫦
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Luke Taplin-McCallum
Luke Taplin-McCallum@luketapmc·
Joint aches suck at any age. Common ones people reach for are collagen (10-20g daily), omega-3 fish oil, and sometimes MSM or turmeric/curcumin for inflammation. Magnesium can help with muscle cramps too. Start with one or two and see how you feel rather than stacking everything at once. I used to overlap on a bunch of supps and waste money until I built Evidose (evidose.app) that pulls from over 50,000 research papers to break down what's actually backed
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SHAY not SEYI
SHAY not SEYI@lovin_a_shay·
Joint ache want to use my eyes to see shege!! I’ve got the bones of an old lady at this age?? Kindly recommend supplements 🙏.
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Leddy
Leddy@LeddyLLC·
4 minerals most people are chronically low in (and the richest food sources for each): 1. magnesium.
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Luke Taplin-McCallum
Luke Taplin-McCallum@luketapmc·
I kept wasting money on supplements and realised I was overlapping on a bunch of stuff that hit the same pathways. Got tired of guessing about safety and what actually works. So I built Evidose (evidose.app) that collates over 50,000 pieces of published research to break down ingredients and full stacks.
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Luke Taplin-McCallum
Luke Taplin-McCallum@luketapmc·
This is a pretty solid take. Those four have the strongest research behind them for most people when youre actually low or training hard. Creatine for power and brain energy, mag for recovery, D if youre not outside much. Good call skipping the hype stuff until the basics are covered. If you ever want to test a bigger stack I made Evidose (evidose.app) to pull the real studies on combos. Happy to test your app too btw if you wanna share it
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Luke Taplin-McCallum
Luke Taplin-McCallum@luketapmc·
Spot on about the dosing scam. A lot of blends throw in tiny amounts of ashwagandha or tongkat just for the label and it does basically nothing. Real studies use much higher doses for any effect. Better to buy single ingredients and dose them properly. I put together Evidose (evidose.app) exactly to check actual evidence levels on stuff like this.
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Testosterone Maxing
Testosterone Maxing@testomaxing·
The Testosterone Apothecary A complete breakdown of: • what supplements actually work • exact effective dosages • what to avoid • how to stack properly • what’s worth your money (and what’s not) testomaxing.gumroad.com/l/supplements
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Testosterone Maxing
Testosterone Maxing@testomaxing·
7 ALARMING Things You Should Know Before Buying ANY Supplement Don't get SCAMMED (Supplement companies hate me for this)🧵
Testosterone Maxing tweet media
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Luke Taplin-McCallum
Luke Taplin-McCallum@luketapmc·
Yeah creatine pulls water into your muscles so that quick weight gain is normal at the start. Most people just aim for an extra litre or two of water a day and it levels out. The strength and recovery benefits are still worth it for a lot of folks. If youre running it with other stuff I made Evidose (evidose.app) to check the research on the whole stack
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Luke Taplin-McCallum
Luke Taplin-McCallum@luketapmc·
Sorry to hear that. Quality control on NMN is all over the place especially from big marketplaces. A lot of people end up testing their own or sticking to brands with third party verification. If youre still thinking about NMN or similar longevity stuff I built Evidose (evidose.app) to pull real research on effectiveness and safety.
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Mother Mandy
Mother Mandy@Mother_Mandy·
I can’t believe I trusted Amazon with this. I should have done more research and demanded clearer disclosures before buying NMN supplements from you. Now I have no idea if what I received is even the real thing or good quality. Since I already purchased it, I’m stuck wondering whether I should throw the whole bottle away or pay to get it lab-tested — and I shouldn’t have to be thinking about any of this. Because I’m worried about overdosing or putting unknown substances in my body, I feel forced to finish the entire bottle before I can safely go back to my local health food store and buy a trusted version. That’s ridiculous. It’s messed up that Amazon even sells supplements like this with so little transparency. Do not buy NMN (or anything similar) from Amazon. Fuck you, Amazon — you’ve really altered the trajectory of my health decisions in ways I never expected. Never again.
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WG UPDATES
WG UPDATES@FanMaga12551·
Real question… If you could save millions of lives without anyone knowing it was you, would you still do it? Yes ❤️ No 💭 Drop your answer below.
WG UPDATES tweet media
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Luke Taplin-McCallum
Luke Taplin-McCallum@luketapmc·
Smart to check for interactions. Magnesium and glycine are usually fine together and a lot of people like them for calm and sleep. NAC can be helpful too but starting new things one at a time makes it easier to tell what is doing what. I made a tool called Evidose (evidose.app) that checks stacks against published studies if you want to run your list through it.
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alexplays
alexplays@alexplaysvg·
@BasedBiohacker Should I take a break from my usual stack while I try it out to see how it affects me? Any risk of unusual interactions with other compounds? Magnesium, glycine, NAC, etc?
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BasedBiohacker
BasedBiohacker@BasedBiohacker·
reminder to always take your bromantane with l-tyrosine, or else you might be wasting precious soviet powder. bromantane upregulates tyrosine hydroxylase and AADC; the two enzymes that convert l-tyrosine into dopamine. without adequate l-tyrosine as raw material, you're running on fumes. l-tyrosine is the substrate that makes the upregulation actually produce something. take it.
BasedBiohacker@BasedBiohacker

clinically diagnosed with severe ADHD as a child → 25 mg bromantane → no longer procrastinating work western healthcare buried soviet pharmacological greatness to shield their profits, and normal everyday people suffer because of that every single fucking day.

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Luke Taplin-McCallum
Luke Taplin-McCallum@luketapmc·
10g collagen at night is pretty common but the evidence for big sleep improvements or Oura changes is still pretty light for most people. It can help with skin and joints over time though. Might be worth trying 5 to 10g for a few weeks and see how you feel. If you combine it with other supps I put together Evidose (evidose.app) to look at the research on stacks like that
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Ryan Phillips
Ryan Phillips@RyanPhilli97630·
@AlpacaAurelius "Wow, is taking 10g of collagen before bed really that effective? Did you notice any significant changes in your Oura Ring data? My sleep has always been just 'okay',do you think I should give it a try, too?"
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Luke Taplin-McCallum
Luke Taplin-McCallum@luketapmc·
Good point on the brain side. A lot of people only think creatine is for lifting but the research shows it helps with mental energy too especially if sleep is off. The sports science data is super solid after all these years. If youre stacking it with anything else I made Evidose (evidose.app) that pulls from the studies to spot any issues.
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Mike | N1 Wellness
Mike | N1 Wellness@n1Wellness·
Creatine isn't a bodybuilding supplement. That's a 1990s framing. Your brain uses 20% of your body's ATP. Creatine directly replenishes it. A 2018 meta-analysis of 6 RCTs found 5g/day improved short-term memory and reasoning speed — especially under stress or sleep deprivation. It's also the most studied supplement in sports science. 700+ studies. Consistent safety data across decades. If you're taking one supplement, this should probably be it. #creatine #biohacking
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Luke Taplin-McCallum
Luke Taplin-McCallum@luketapmc·
Strong take—creatine, mag glycinate, and D+K2 really do have the best evidence for most guys. Creatine for performance + cognition, mag for sleep/stress, D when deficient. Solid foundation before adding anything else. If you're testing a full stack, I built Evidose (evidose.app) to cross-check against published research."
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The Lazy Biohacker
The Lazy Biohacker@LazyBiohackr·
500+ supplements on the market. Most are expensive urine. Here's what the actual evidence supports for men 25-45: 🟢 Creatine The most studied sports supplement in history. Consistent benefits for both physical performance and cognitive function. About $0.20/day. 🟢 Magnesium glycinate Roughly 48% of adults are deficient. Research suggests consistent improvements in sleep quality, muscle recovery, and stress response. Form matters: glycinate over oxide. 🟢 Vitamin D3 + K2 If you work indoors, you're probably deficient. Most people test at 20 to 25 ng/mL and call it fine. Test first. Supplement to 40 to 60 ng/mL. That's the stack. Everything else is marginal noise until these three are dialed in. Not medical advice. Just the evidence filtered.
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