Mark Bavisotto

My Grandfather taught me 3 invaluable life lessons that have been instrumental in my success in business. 1. Be Nice to everyone: My Grandfather from a very young age has always told us to be nice to everyone because you never know what that person is going through. Business can be stressful for everyone and it costs you nothing to be nice no matter what is going on at that moment. We are all just humans trying to do our best. 2. Listen before you speak: On many occasions growing I would interrupt my Grandpa and he would always say, "The key to a meaningful conversation is to listen first and speak second. " Make sure you master the art of listening if you want to build more business relationships and close more sales. 3. Have a great work ethic: Grandpa was a modest man who served in the 101st airborne during WWII. He said the one thing that helped him rise to Master Sergeant was having a great work ethic. He would constantly remind me that the one thing you can control in your life is how hard you work. In business, if you want to succeed you must work harder than everyone else around you. Let me be clear, working harder doesn't mean pulling all-nighters, but using your time efficiently to complete manageable tasks. How do you eat an elephant? One bite at a time.

@thadbrown7 Kozak should go in for Karik. Helenus should go in for Norris. Metza and Kesserling should go in for Stanley and Timmons. I think Lyon's fine. I wouldn't make a move in goaltending right now.

@markbavisotto Could it get any worse is the only part of this I think is justifiable and I think if that’s your argument, you’re probably already dead

I’m skeptical about #Sabres turning to 19 year old as a savior. But when Isak Rosen was traded, Helenius had to become THE star in Rochester. He lived to up every inch. Repeatedly scored big goals. Plenty like this, mostly on his own. If there’s a 19 year old who’s ready, it’s this guy.

@Bulldogwgr @OwenP29 has been a breath of fresh air on the radio.

Pretty cool

@bryan_johnson What about Kate's Vagina?

People mistakenly believe peptides are only good. Peptides can be bad, too. They can cause adverse effects. Some dangerous. I did a peptide experiment and measured its effects in my body. The results are complicated. I tried a peptide called CJC-1295. It pushed my growth hormone up by ~8x. That’s good. That’s what it was supposed to do. But, it also came with adverse effects: > increased my morning fasted blood sugar up 20% > increased stress hormone by 12% > tanked my REM sleep by 23% > made my pancreas work 53% harder and was still losing to rising blood glucose > increased my insulin resistance by 50% These were the most obvious side effects, and I only ran a very narrow panel for this experiment. So I’m sure there’s more. I stopped after two doses, without even reaching the intended target dose. For those of you new to peptides, your body sends instructions to itself using tiny chemical messengers called peptides. There are thousands of them. For example, GLP-1s are drugs that take an existing class of short-lived peptides and modify them to extend their activity duration, which turns them into drugs, following rigorous clinical testing. CJC-1295 is one of those peptide-drugs. It tells your brain to release more growth hormone. Growth hormone is your body's signal to build muscle, repair tissue, and recover. However, and like most grey market peptides, CJC-1295 did not succeed its clinical trial, and hence never became an “official” drug. There is a version called CJC-1295 with DAC. DAC is an attachment glued onto the peptide that makes it last for days in your body instead of hours. One shot, longer effect, just like GLP-1s. Why people use it: more growth hormone could mean better recovery, leaner body, faster healing. The experiment I completed. Two injections a week of CJC-1295 with DAC: > 1.2 mg > 1.8 mg 48 hours after the first injection I was nearly comatose. It felt like severe jet lag, the type you’d feel after traveling nine time zones. My sleep was wrecked and I felt continuously awful. My REM sleep dropped by 23%. REM is when your brain processes memories and repairs itself. Less time for my brain to repair itself. During the experiment, I never felt rested and always fatigued. Why we chose CJC-1295 with DAC. Some will say we picked the wrong peptide. They will say I should have used a different version, CJC-1295 without DAC, mixed with another peptide called Ipamorelin. We went with CJC-1295 with DAC instead as it has the most controlled studies. CJC-1295 with DAC has 2 controlled trials in healthy adults. Ipamorelin alone has 1 controlled trial in healthy adults, plus 1 study that failed when they tried it on bowel surgery patients. The mix of the two has zero controlled trials. On Ipamorelin, it copies a chemical called ghrelin, the one that makes you hungry. On its own it gives you a quick burst of growth hormone that fades fast. It does not keep your longer acting growth signal (called IGF-1) up. Clinics mix Ipamorelin with CJC-1295 no-DAC because the two together are supposed to work better. But we don’t know if that’s accurate because we don’t have trial data. This is a problem with peptides. Almost none of them have been tested properly. We are flying blind. Most of what people use is based on what someone said online, what a clinic claims, or what a friend reports from their subjective feelings. Peptides have the potential to be great when well-studied.

@BR_OpenIce The NHL is the most rigged sport ever. Give me a fucking break. Poor Vancouver fans.

THE TORONTO MAPLE LEAFS HAVE JUST WON THE DRAFT LOTTERY 🤯

@SHKIIIsGhost I played with his son, and he was my coach for a little bit. I think in pee-wees, and he was quite the character.

He coached the Jr. Sabres junior team. Nobody in that locker room had heard anyone swear that much...ever. He could insert an F-bomb in the middle of a word like nobody else. Re-f**kn-diculous was a fav.

@theinformation @rocketalignment IS this reporter a cartoon character?

Elon Musk was “clueless” under cross-examination by OpenAI’s lawyers when asked about AI safety. @rocketalignment explains: "When OpenAI's lawyer asked Musk some very basic questions about the industry's best practices around AI safety, Musk was clueless.” “He was asked about safety cards or system cards... And he didn't know what that even was."

@Codie_Sanchez Sorry, Codie, prompting is dead.

I'll die on this hill. Teaching a 15 year old how to prompt is more useful than another year of SAT prep.

@stoolpresidente Model Franchise for cheating

Mike Vrabel did a Q+A with Patriot season ticket holders last night. Word on the street is he got a standing ovation when he arrived. Patriots fans aren’t into gossip and tabloid fodder. We are into winning super bowls and forgiveness. Model franchise.

@PeteGuelli Would love to fly in from Raleigh

So who needs to be at Game 5?#LetsGoBuffalo #sabrehood

@JeremyWGR In the hunt 🤣

My word

I think what Alex is saying is that this is how BB operates. He is so worried about draft capital that it constantly clouds his judgment and jeopardizes the present. This has resulted in wasting so many of JA's good years. I believe subconsiously, HE was so worried about losing a second round pick, that it became a game to get that back, even if it meant getting rid of 26... Just draft good players for your fucking QB. I'll say this like I said it before: they fired the wrong guy.

@alexbrasky Thanks for the follow back… lol

The difference between Keldric Faulk and Zion Young sending you that bad bro? They can still get players who can help them right now this evening. It’s like we’re ignoring how mid-heavy this draft is.

@Jason im in

We started an AI founder twitter group... reply with "I'm in" if you're a founder and want to be added

@Matt_Bove Inexcusable…

Do they start Lyon on Thursday? I don't want to be premature here, but I think it's a valid question.

@PeteGuelli @KeyBankCtr Based on Josh's press conference today, it's definitely him.

Rolling a special guest out Tuesday just to see if @KeyBankCtr can get any wilder!🥁

@SneakyJoeSports I think it would have been goaltender interference anyways.

My jaw hit the floor when he didn't shoot this

@BuffaloSabres @googoodolls Let's go.

@MikeMonaco_ Sweet, so the NHL gives us a Boston guy doing the game. Can't wait to listen to his nonsense.

See you soon, Buffalo. Bruins. Sabres. RIP to my eardrums.

@businessbarista 70/30

human skill issue, not a technology issue.

@mattshumer_ If you haven't found out by now, Anthropic has a great PR and Media team around AI doomerism to stroke fear.

This is absolutely fucking terrifying. Anthropic's rumored Mythos model is real. And it's so powerful that they can't release it to the public. We're beyond benchmarks now. This model, in the wrong hands, is a cyberweapon capable of mass destruction.