Michael McCarthy

Talent hits a target no one else can hit. Genius hits a target no one else can see.

@OrinKerr Blue > Black

I wonder how many older lawyers default to using pens with blue ink instead of black ink because, back when you would file a paper original and a paper copy, blue ink was the way the clerk could tell which was which, so by default it just made sense to use pens with blue ink.

@NortonMpls @SwillWill_ Who bikes the 6 months out of the year with snow?

@SwillWill_ Bike lanes probably make up like 2% of paved surfaces in downtown Minneapolis. It’s ridiculous to blame bike lanes for anything.

Blaming a few bike lanes in Minneapolis for the national shift to remote work causing the decline of daily traffic in central business districts is just embarrassingly naive. The Star Tribune dilutes the reputation of its journalism by publishing bullshit editorials like this.

@NortonMpls Matt Hemsley is insanely smart and bright. It's naive to categorize this as a bullshit editorial.

@johncumbers This man is amazing

The first human age-reversal trial is officially happening. But before the FDA cleared it, Harvard professor David Sinclair had to pull off a mice experiment most scientists thought was impossible: "These mice had their optic nerve regenerated. We were able to show that using [the information theory of aging] method we could cure blindness in animal for the first time." Since then, he also discovered you could treat and reverse diseases like Alzheimer's, multiple sclerosis, ALS, kidney disease and liver disease in mice too: “It's not just the eye that can get reversed and cured of diseases. It's seemingly every part of the body.” It's what he calls "a universal reset of the body." He confirmed his method also worked in monkeys. Now humans are next. The FDA just cleared the first age-reversal trial. Life Biosciences raised $80 million to make it happen. As he put it: "The eye is just the beginning. We believe we can treat every tissue—a whole body reset."

Truth

@MartinShkreli FDA should hurry up and approve them then

DO NOT purchase fake peptides OR ELSE

@WallStreetApes Most don't realize modern day factories do not create jobs. Instead, they are huge CAPEX investments that eliminate workers.

New fully automated stacking cranes at the Port of Long Beach The Long Beach Container Terminal is the first fully automated container terminal in the United States, with both driverless cranes and driverless vehicles to transport containers 572 full time jobs were eliminated. Full automation began in 2021

@grok @Wasquen @davidasinclair @Y_Ryan_Lu @Nature @sinclairfriends @grok how can I sign up for clinical trials

Nothing you can take right now directly leverages this—it's experimental gene therapy using OSK factors (three Yamanaka factors, no c-Myc) delivered via virus, toggled by doxycycline in trials. Sinclair's team showed it rejuvenates tissues in mice without full reset or tumors. Human trials (via Life Biosciences) start in 2026 for glaucoma/NAION eye conditions. No pill or supplement mimics it yet. Stick to evidence-based basics: exercise, calorie control, sleep, and consult a doc for personalized advice. Exciting field, but not consumer-ready.

You're confused. Let me explain: My student @Y_Ryan_Lu worked for years to find a SAFE way to reprogram cells so they'd only RE-GAIN identity, not LOSE it, as Prof Yamanaka showed We tried innumerable combos to find the solution Story is @Nature now nature.com/articles/d4158…

@MartinShkreli @ericswalwell Martin destroying Eric was not on my bingo card for this year 🤣

i need to speak to someone from the @ericswalwell campaign. ive received a video of him being intimate with a woman who does not appear to be his wife and would like a comment before posting.

@macastel3 Dubai

What is the next Dubai? Any idea?

@NortonMpls @GeoffreySerdar Retail could come back. It's just choosing not to come back in the Uptown Pocket due to the downward spiral.

@GeoffreySerdar Mayor Frey is in charge of public safety in uptown, he’s been ineffective in a lot of areas. My point on retail is that it’s never coming back and uptown should move forward.

Uptown vacant retail cant just turn into housing. Capital only goes to safe spots with real outside spending and growth potential. Not dead zones with no vibrancy. Uptown blew up with apartments back when it was the suburban fun zone. Burb kids and their money flooded the Hennepin corridor and kept everything thriving. That engine is gone now with Minneapolis declining overall. No outside dollars coming in anymore. More than anything we gotta get the junkies and criminals out first. Open drug use and homelessness are pushing everyone away. Security at that parking garage next to Seven Points had to throw people out 46 times in January 2025. This January it exploded to over 1200 times. Thats how bad the disorder is. Without clearing that mess more dollars keep leaving. Dont take my word for it. The proof is rents still dropping or flat. Uptown is already one of the cheapest urban rental markets anywhere. Median rent 1473 as of April 2026. Thats 23 percent below national average per Zumper. Average around 1699 per RentCafe with basically zero growth. Rents are soft because decline plus crime left too much supply and not enough demand. Uptown West Calhoun vacancy at 7.3 percent. Commercial values dropped another 4.9 percent last year. Somali Mall works because outsiders drive in with money made elsewhere and pump it into their businesses. Without fixing safety first and bringing back outside spending as the base new private housing wont happen. Only way is government subsidies. That means squeezing taxpayers more raising costs chasing businesses out and speeding up the strangulation cycle. Is falling rents what you want. Its already happening and proving the exodus. But then why add more housing while rents keep dropping. Whats your real plan to rebuild vibrancy first. How do we break this without hitting the root causes. Would love to hear what @rhett_carlson thinks @NortonMpls @BradSchaeppi When Sherman, Walton, Gassen all say never again - all of who really put effort into the area, all won’t - what makes you think there will be residential development?

@NortonMpls False. They had great shopping. Those stores will never return.

The part of Uptown people in the suburbs seem to mourn was effectively a destination outdoor mall that’s always had terrible parking, when these buildings are replaced with housing it will be better for the community

@signulll Politics

rent seeking is likely the world’s second oldest profession. what’s third?

@zerohedge They likely took all the client files

*JONES DAY LAW FIRM SAYS IT WAS BREACHED, HACKERS STOLE DATA *JONES DAY SAYS ATTACKERS ACCESSED FILES FROM 10 CLIENTS

@MIAviationKing A banana bankruptcy

So this is... *check notes* ...normal shit an airline does in Chapter 11 bankruptcy (for a second time, on the way to Chapter 7) when most of its cash is restricted. I see... interesting...

@dilanesper @kcjohnson9 Ooooof

This is a massive, massive story in the world of law practice (and something I assumed would happen to a big firm at some point).

@matteopelleg @FrancisSuarez ✅

Buying a Tesla in 2026 is like buying an iphone in 2010 You know eventually everyone will get one

@champtgram @FrancisSuarez Beautiful

people who don't live in Miami & think it's all clubs/parties, let me introduce you to South Miami > multi-generational families > countless farmers markets > 100 year old churches > no clubs > gorgeous neighborhoods > zero state income tax one of the last bastions of the USA

@dieworkwear What is your recommendation for trouser waistlines - side tabs (buckled or buttoned) or a clean finish without adjusters?

Many jackets can cost $2k and more. Much depends on the material and how it's made. You don't see this bc you are disconnected from the production process and only think about clothes as objects. Marx called this commodity fetishism. IG ninapenlingtonbespoke and sartoria_salino

Amen