Eli Van Allen

There’s never been a more exciting time for all of us to take on cancer, together.

Link to the panel: youtube.com/watch?v=rPV9r0… Link to Ken et al's MatchMiner-AI tool: arxiv.org/abs/2412.17228 We are always looking for ways to thoughtfully support of these efforts, reach out for more!

Had fun discussing AI innovations in health care with @TheAtlantic @tgoetz, highlighting work by @kenlkehl @ecerami @DFCIPopSci on AI for clinical trial matching in oncology + other exciting applications of AI across @DanaFarber theatlantic.com/sponsored/lill…

A true joy celebrating the 25 year anniversary for @CampKesem last weekend with the one-and-only Iris Wedeking - a remarkable org, impacting cancer patients and their families (+ inspiring clueless college kids like me!) ... a genuine privilege to be part of this family

Today at #AACR26: Noah Fields, MS, of @DanaFarber’s @VanAllenLab, presents findings from a familial cancer study suggesting that high-resolution germline genetic testing could benefit patients with familial cancer. ➡️ bit.ly/4crIeQl

LBA1/Plenary #ASCO26: PROTEUS trial Perioperative apalutamide + ADT vs. placebo + ADT with radical prostatectomy in HR localized or locally advanced PC Our very own #DrMaryEllenTaplin from @DanaFarber_GU will take the stage at #ASCO26 and present phase 3 PROTEUS trial. This is a key multimodal treatment question and could shift the paradigm on how we think about systemic therapy in the perioperative setting. Dr Taplin has worked on countless Neoadjuvant Strategies in prostate cancer and it is rewarding to see her work materialize at the big stage ! @DanaFarber @DanaFarber_GU @ASCO @OncoAlert

Fantastic work from @JoYatesResearch on multimodal AI for spatial biology discovery - see her notes below for more info! @DanaFarber @broadinstitute @CarolineUhler @Schmidt_Center

Link to paper: sciencedirect.com/science/articl…

In our latest, we made + examined simulation frameworks for biologically-informed neural networks in cancer genomics and showed how germline + somatic integration shifts gene importance rankings (👋 BRCA2), even w/o gains in predictive accuracy... Congrats Gwen Miller et al!

📣 We’re hiring a computational genomics postdoc! 📣 Our lab at @DanaFarber is looking for a postdoctoral fellow — details👇

Link to paper: science.org/doi/epdf/10.11…

In our latest, we used single cell ATAC to take a deep dive into kidney cancer chromatin programs and their relation to mutations in epigenetic regulators + interferon + endogenous retroviruses - congrats Sabrina Camp, Kevin Bi et al!

@daniela_oaks @mtzsaid @AlethiaAlvarez @DorianGarciaMD @patydesu @EstefVazque @Christian_moli_ @LIIGH_UNAM Congrats!!!

Muchas gracias Oscar y @mtzsaid, @AlethiaAlvarez, @DorianGarciaMD del INCan por su gran apoyo,y @patydesu, @EstefVazque, @Christian_moli_ del @LIIGH_UNAM por liderar este proyecto!!! #cienciamexicana

@DanaFarber @harvardmed @bethisraellahey @BrighamWomens (I should clarify, at least I thought it was fascinating lol)

Here's a link to the paper: science.org/eprint/IQZ5T27… Huge team effort via the David Liposarcoma Initiative @DanaFarber @harvardmed @bethisraellahey @BrighamWomens et al

Here, we found out how liposarcomas - rare cancers arising from adipose precursor cells - can switch from indolent to lethal states A fascinating set of insights that even includes GLP-1 biology + therapeutics in cancer! Congrats Dr. Erica Pimenta et al @DanaFarber @ScienceTM

“This rare cancer, liposarcoma, gives us a unique opportunity to study what GLP-1 drugs do to cancer cells,” @DanaFarber’s Dr. Erica Pimenta tells @washingtonpost about her research into whether the weight-loss medications could be a treatment pathway. Read more: bit.ly/4k08KUr

Link to paper: sciencedirect.com/science/articl…

Here's our latest, where we explored how to augment LLMs with constantly evolving precision oncology knowledge (h/t @moalmanac), followed by collaboration with medical oncologists to test their queries - congrats Helena Jun, et al!

@EricTopol Thanks so much for highlighting our work!

Enhancing accuracy of cancer care with a large language model cell.com/cancer-cell/fu…

Link: nature.com/articles/s4156…

Here's our latest, a perspective on the convergence of machine learning and genomics for precision oncology - exciting for 2026 and beyond! Congrats @brendan_reardon @AedinCulhane @NatureRevCancer