Maria Passarelli, MD, PhD

82 posts

Maria Passarelli, MD, PhD

@mpassarelli15

PGY-1 @TheBCRP | tRNA/translation enthusiast | @TriIMDPhD '23, @RockefellerU '22, @Yale '15 | Avid baker, artist, songwriter.

Boston, MA Katılım Kasım 2019

357 Takip Edilen343 Takipçiler

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Maria Passarelli, MD, PhD@mpassarelli15·14 Mar

Very excited to share our paper, identifying a tumor-suppressive tRNA synthetase, published today in @naturecellbiol! nature.com/articles/s4155… @sohailtavazoie @genophoria @triimdphd @rockefelleruniv… 1/11

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Sohail Tavazoie@SohailTavazoie·23 Eki

Transfer RNAs (tRNAs) are increasingly found to play dynamic and critical regulatory roles in cancer progression. Alexandra Pinzaru's review describes this exciting area of research: nature.com/articles/s4156…

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Maria Passarelli, MD, PhD@mpassarelli15·19 May

Eight years flew by! So proud to have graduated from @WeillCornell alongside these incredible classmates. Forever grateful to all of my mentors @SohailTavazoie and many more @TriIMDPhD, and @RockefellerUniv. Cannot wait for this next chapter as a pediatrician-scientist!

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Maria Passarelli, MD, PhD@mpassarelli15·7 Nis

@SohailTavazoie @BostonChildrens @MountSinaiNYC @RockefellerUniv @TriIMDPhD @WeillCornell Thanks so much Sohail, couldn’t have done it without your support! Looking forward to this next step in the physician-scientist journey. Will come back to visit for lab BBQs !

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Sohail Tavazoie@SohailTavazoie·7 Nis

Incredibly proud of our lab's physician-scientist graduates @mpassarelli15 and Kristina Navrazhina, who matched in pediatrics @BostonChildrens & dermatology @MountSinaiNYC, respectively!! The future is in very good hands! @RockefellerUniv @TriIMDPhD @WeillCornell

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Sohail Tavazoie@SohailTavazoie·12 Ara

The amazing @TriIMDPhD student Lisa Earnest-Noble's paper is out showing that two so called 'synonymous' isoleucyl tRNAs opposingly regulate breast cancer & metastasis by driving distinct gene regulatory programs. @RockefellerUniv also thx to @genophoria nature.com/articles/s4301…

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Eric Topol@EricTopol·22 Haz

"We find that, in both patients with breast #cancer and mouse models, generation of CTCs [circulating tumor cells] is highly restricted to the rest phase" Should anti-cancer therapy be timed to a person's circadian rhythm? nature.com/articles/s4158… @Nature

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Maria Passarelli, MD, PhD@mpassarelli15·29 Nis

Excited to see this in press! Elegant work by @RyanMoyMDPhD, giving us yet another reason to drink our ☕️

Sohail Tavazoie@SohailTavazoie

A caffeine sensitive ER ITPR3 receptor releases calcium, which activates RELB (NFKB) TF to drive Colon CA liver metastatic colonization by amazing team @RyanMoyMDPhD, @ZanderNguyen , Jiamin loo, nori Y. authors.elsevier.com/a/1e%7Ebk5Sx5g… Drink your coffee! @RockefellerUniv

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Maria Passarelli, MD, PhD retweetledi

Nature Cell Biology@NatureCellBio·15 Mar

A study led by @SohailTavazoie & @genophoria shows that leucyl-tRNA synthetase suppresses breast cancer development via upregulating translation of growth-inhibitory genes. PDF: rdcu.be/cI2qE nature.com/articles/s4155…

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Rockefeller University@RockefellerUniv·14 Mar

A new study from @SohailTavazoie's lab in @NatureCellBio identifies a tumor-suppressive tRNA synthetase. The findings shed light on the role of translational control in cancer development. nature.com/articles/s4155…

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