Murrell Lab

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Murrell Lab

Murrell Lab

@murrell_lab

Laboratory of Living Matter. Studying cellular mechanics and force generation in every way we can.

New Haven, CT Katılım Nisan 2017
313 Takip Edilen1.2K Takipçiler
Murrell Lab retweetledi
Nature Physics
Nature Physics@NaturePhysics·
Self-organized criticality can occur in cellular systems, but its origins remain unclear. Now it is shown that cytoskeletal criticality is influenced by the F-actin architecture and myosin active stress. nature.com/articles/s4156…
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Murrell Lab
Murrell Lab@murrell_lab·
This piece of work cannot be done without the collaborative efforts with the @GareginPapoian lab at @UMD_CollegePark . We show both in vitro and in silico that actomyosin cortex exhibits criticality which can be tuned via mutual feedback between architecture and active stress.
Zachary Gao Sun@SunGaoZachary

This important piece of work from my PhD @murrell_lab is FRESHLY out of the oven in @NaturePhysics ! It illustrates how architecture and active stress mutually regulate Criticality and exhibit Anderson Localization-like phenomenon. Paper link: nature.com/articles/s4156…

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Murrell Lab
Murrell Lab@murrell_lab·
Our latest paper in Nature Physics shows the actomyosin cortex self-organizes to a critical state via mutual feedback between dynamical F-actin structural remodeling and active stress. This further links cytoskeletal criticality to Anderson Localization. nature.com/articles/s4156…
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Murrell Lab retweetledi
Yale West Campus
Yale West Campus@YaleWestCampus·
Congratulations to the Yale Systems Biology Institute’s Michael Murrell, who has received support from @HFSP for an has intercontinental project spanning the US, UK and South Africa to uncover the driving force in cyanobacteria bit.ly/MurrellHFSP
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Murrell Lab
Murrell Lab@murrell_lab·
Get your hands into oobleck - a material that feels as hard as a block of cement when you slap its surface, yet is too liquid to hold in your hand! Soft matter physics and Biophysics can be so much fun!
Zachary Gao Sun@SunGaoZachary

The second Squishy Science Sunday will take place on Sunday March 16th, 2025 from 11 am - 3 pm as part of the 2025 APS Global Physics Summit. We invite the scientifically curious of all ages - children and adults -  to explore the fascinating world of soft materials!

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PRX Life
PRX Life@PRX_Life·
Congratulations to @SunGaoZachary and @melodydibona who were awarded the Physical Cell Biology Student Award and Early Career Award at the @biophysicalsoc meeting today. We’re proud to sponsor both awards and recognize Zachary and Melody’s great work. 🎉
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Murrell Lab
Murrell Lab@murrell_lab·
Have you ever heard of the addition of connectivity without the penalty of an increase in rigidity of the network? The work piece of our latest rheological study on in vitro cytoskeletal materials by our PhD student, Zachary Sun, is finally out today!
Zachary Gao Sun@SunGaoZachary

Here’s our latest paper published in Physical Review Letters! DOI:doi.org/10.1103/PhysRe…. We show the F-actin severing protein, cofilin, crosslinks F-actin networks under the acidic condition, and minimizes the penalty of connectivity for rigidity, with mechano-sensitivity.

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Diz-Muñoz Lab
Diz-Muñoz Lab@diz_lab·
New Preprint! How can cells polarize in the absence of a stimulus? We suggest a surprising biophysical mechanism, protein caging! We reveal how the complex mechanical interactions at the cell surface lead to symmetry breaking. biorxiv.org/content/10.110…
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Yale West Campus
Yale West Campus@YaleWestCampus·
West Campus scientists at the Systems Biology Institute have discovered the thermodynamic principles underpinning energy use in our cells - and a potential pathway to tackle diseases like cancer bit.ly/wave-patterns @murrell_lab @NaturePhysics
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Murrell Lab
Murrell Lab@murrell_lab·
Happy new year from LLM! Our latest article on in vitro reconstituted systems: 'Cofilin-mediated actin filament network flexibility facilitates 2D to 3D actomyosin shape change' in EJCB special issue 'In vitro reconstitution of cytoskeletal processes' sciencedirect.com/science/articl…
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Communications Biology
Communications Biology@CommsBio·
Visualization of f-actin within liposomes during their adhesion, spreading and rupture reveals mechanical interactions of membrane and cytoskeleton can lead to complex cellular assembly in absence of cellular biochemical regulation. @murrell_lab nature.com/articles/s4200…
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Shiladitya Banerjee
Shiladitya Banerjee@ShilaBanerji·
Very proud of this collaboration with @murrell_lab and the perseverance of the authors through a long and exhausting peer review process.
Physical Review X@PhysRevX

Observations of pressure-driven motion of cells reveal a novel type of cell migration and cooperation between cellular- and tissue-level forces, with implications for cancer cell movement and early organism development. Read go.aps.org/3QRyUJm #PRXjustpublished #openaccess

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Murrell Lab
Murrell Lab@murrell_lab·
A long but rigorous and constructive review at @PhysRevX finally resulted in our latest manuscript, where we demonstrate a novel pressure-driven flow of cells out of a cell aggregate.
Physical Review X@PhysRevX

Observations of pressure-driven motion of cells reveal a novel type of cell migration and cooperation between cellular- and tissue-level forces, with implications for cancer cell movement and early organism development. Read go.aps.org/3QRyUJm #PRXjustpublished #openaccess

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Murrell Lab
Murrell Lab@murrell_lab·
Yale News covered our recent work on pressure-driven flows in cell aggregates that appeared recently in @PhysRevX. We thank @YaleWestCampus for their support and Jon Atherton for condensing 3 papers into this great story.
Yale West Campus@YaleWestCampus

The @murrell_lab has taken a fresh look at how cells move, revealing similarities between the behavior of #cancer cell tissue and the simplest water droplets bit.ly/droplets-cells @PhysRevX @YaleSEAS

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Keşfet

@GareginPapoian @UMD_CollegePark @yalephysics @HFSP @SunGaoZachary @BiophysicalSoc @NaturePhysics @PhysRevX