Odessa Jiang

Warmest congratulations to Nobel Laureate, David Baker! We are so incredibly proud of you and your contributions to the field of protein design. Onward and upward!

This year’s chemistry laureate David Baker created the first protein that was entirely different to all known existing proteins. The protein, Top7, was a bolt from the blue for the researchers working on protein design. Those who had previously created new proteins had only been able to imitate existing structures. Top7’s unique structure did not exist in nature. Also, with its 93 amino acids, the protein was larger than anything previously produced using de novo design. #NobelPrize

BREAKING NEWS The Royal Swedish Academy of Sciences has decided to award the 2024 #NobelPrize in Chemistry with one half to David Baker “for computational protein design” and the other half jointly to Demis Hassabis and John M. Jumper “for protein structure prediction.”

More EvoPro applications to come! Until then, you can find the code on the Kuhlman Lab GitHub. Happy designing! 😊🥼 ⚙️github.com/Kuhlman-Lab/ev… 📖pnas.org/doi/10.1073/pn…

Besides finding a ⚖️ bw affinity & protease-dependent activity, the coolest aspect of the best performing masks is just how diverse the structures and interface contacts are from each other & from the natural ligand (⚫️). 😎🤓

SO excited to introduce EvoPro, a protein design pipeline that iterates bw structure prediction & seq diversification that engineered a ... 1 nM binder (design 5)! This was a huge group effort, made possible by @amritanalla, @tkinjo8 , Nick, and Brian. 🥳

#AcademicChatter #AcademicTwitter

@ramith__ Wow, thanks so much @ramith__! 😍 That means a lot to me!

@oda_sci @ProteinBoston Loved the simplicity (must've taken a lot of effort) of slide design and the flow of the presentation that day 😃👌

exciting update - you can now check out the recording of @oda_sci's fantastic seminar from September 👇 youtu.be/ojuJ9MomfQQ

“Who are you wearing?” “thermo.”

“For the 20 years that we worked together before anybody knew about us or cared it was literally the two of us sitting side by side at a bench and working together. Usually at 3 or 5am we would be emailing each other with new ideas.” - 2023 medicine laureate Drew Weissman on his partnership with his co-laureate Katalin Karikó. Keep an eye out for our telephone interview with Weissman, coming soon!

I'm super excited to present my research on interface design to the incredible @ProteinBoston community! Make sure to stop by and say hi! ☺️👋 Special thanks to the amazing organizers @bahl_lab, @nickpolizzi_ , and @sokrypton 👏

HAPPY PRIDE! 🩷🩵🤍❤️🧡💛💚💙💜

@Shadow_UNC Such a dream! Now, I can't wait to watch @Shadow_UNC grow under new leadership! 💫

Congratulations to our PhDs, Odessa & Hannah! As co-founders and long-term leaders of SAS, we are so grateful for all of your contributions. Leading & running SAS during your PhD in addition to completing your research exemplifies your values for sharing science with students.

What made month one so fun? New biology, new pipettes, a never ending supply of 🍩s, attending @ProteinBoston with my grad school rotation mentor, engaging discussions, and even a little champagne!🍾🥂

I'm so happy to share that I joined @AI_Proteins as a Scientist on the Discovery Team!🦋I'm excited to create a healthier world by harnessing the power of miniproteins! It's been an incredible first month, with much more to come. Until then, some pics of happy scientists! 🧬

Fantastic showing with the NSF GRFP this year! Congrats to awardees @oliviasteiner28, @DhuviKarthikey1, McKenzie Grundy, @cole_398, Eva Mei Shouse, @RRSharp122, and Glory Dan-Dukor, plus honorable mentions for @EberhardQuinn, @addie_coke, @ReaganBullins, and @meganbrienne!