Oscar Sánchez

Excited to share our new paper on PIEZO2 ion channels and their role in mechanical pain sensitivity! 🔬Check out how PIEZO2 mutations lead to nociceptor hyperexcitability and potential implications for chronic pain treatment. Thanks to all collaborators! doi.org/10.1093/brain/…

🥐 Good Morning Everyone! This week's #MicrogliaResearch in Health and Disease edition, supported by @Bims_BiomedNews, is now available! As a scientist passionate about microglia, I’m excited to share my curated selection of publication highlights with you each week. Check out the full list here biomed.news/bims-microg/20… and let me know which research grabs your interest! 🤜🤛 Special thanks to @Bims_BiomedNews and @gavinmcstay2 #Neuroscience #Aging

TENM4 is an essential transduction component for touch and pain biorxiv.org/content/10.110…

👋 Good morning, everyone! This week's #MicrogliaResearch in Health and Disease, supported by @Bims_BiomedNews, is now available! #Neuroscience #Aging As a scientist passionate about microglia, I’m excited to share my curated selection of publication highlights with you each week. Check out the full list here biomed.news/bims-microg/20… and let me know which research grabs your interest! 🤜 🤛 Special thanks to @Bims_BiomedNews and @gavinmcstay2

Sociality shapes mitochondrial adaptations supporting hypoxia tolerance biorxiv.org/content/10.110… 👇 Below a twittorial on Alice Rossi's great paper @Alice_Rossi__ describing the mechanisms of cellular hypoxia resistance in the naked mole-rat!👇

☀️ Good morning, everyone! This week's #MicrogliaResearch in Health and Disease is now available! #Neuroscience #Aging As a scientist passionate about Microglia, I'm excited to share my curated selection of publication highlights with you each week. Discover the complete list here: biomed.news/bims-microg/20…. Which research grabs your interest? 🙏 Special thanks to @Bims_BiomedNews and @gavinmcstay2 for their support!

KI researchers have developed a comprehensive pain atlas, iPain, now available on CellxGene. The atlas, presented @NatureComms, offers valuable resources for future pain research and opens way to better treatment for #ChronicPain and #headache disorders. news.ki.se/new-study-brin…

Piezo2 channels and tactile pain: an intriguing voltage connection New scientific commentary by Jorge Fernández-Trillo, Ana Gomis and Félix Viana academic.oup.com/brain/article/…

October's issue of Brain is now online! academic.oup.com/brain/issue/14…

Proud to present Alice's @Alice_Rossi__ exciting study on how unique molecular adaptations of mitochondrial proteins allow naked mole-rat cells to survive 2 days without oxygen! Sociality shapes mitochondrial adaptations supporting hypoxia tolerance biorxiv.org/content/10.110…

@inwardopen @BjossiM @NDCNOxford @KavliOxford @BiochemOxford @mdt_tseng

#Piezo1 is also strongly blocked by voltage as nicely shown previously by the labs of @JorgGrandl and @GaryRLewin1 doi.org/10.1016/j.celr… doi.org/10.1038/s41467… Ion channel #biophysics provides important insight into #ionchannel function

Sanchez-Carranza @GaryRLewin1 and collegues report in @Brain1878 that #Piezo2 voltage-block regulates mechanical pain sensitivity doi.org/10.1093/brain/… With @anagomisg and J Fernandez Trillo @NeuroAlc I wrote a commentary on this provocative finding doi.org/10.1093/brain/…

Proud to be part of this great job. Congrats @MireiaPampols!

Researchers in Gary Lewin’s lab at #mdcBerlin have identified an ion channel that contributes to chronic pain syndromes, suggesting a new target for pain medications. The study was published in 'Brain.' @Brain1878 @GaryRLewin1 Read more: mdc-berlin.de/news/press/und…

@Lowensteined @SfNJournals 👏🏾

@SchwallerFred @fluorescence_SC @GaryRLewin1

Excited to share our new paper on PIEZO2 ion channels and their role in mechanical pain sensitivity! 🔬Check out how PIEZO2 mutations lead to nociceptor hyperexcitability and potential implications for chronic pain treatment. Thanks to all collaborators! doi.org/10.1093/brain/…

Very happy to announce that our paper showing how voltage block of Piezo2 channels regulates nociceptor excitability is now published in Brain! Great work from Oscar Sánchez-Carranza @osca_90 and colleagues like @fluorescence_SC and @SchwallerFred. academic.oup.com/brain/advance-…

Emerging from X/Twitter hibernation to announce the first preprint of the lab! Naked mole-rat ❤️ keeps beating without oxygen thanks to their specialised glycogen. Spearheaded by @AmandaBundgaar2 in collab with @FrezzaLab - thanks to all involved! biorxiv.org/cgi/content/sh…