Parth Bapodariya
938 posts

Parth Bapodariya
@parth_014
Dy.Section Officer | Mechanical Engineer 🔧🔩 | chess




“Clowns are the pegs on which the circus is hung.” — P. T. Barnum The Ministry of Health and Family Welfare, Government of India, Indian Pharmacopoeia Commission has suddenly woken up to the fact that non-steroidal anti-inflammatory drug (NSAID) like mefenamic acid (mostly prescribed in short term for painful period cramps) causes a side effect called as DRESS syndrome (Drug Reaction with Eosinophilia and Systemic Symptoms), a condition first described in 1936 (!!!) from treatment due to anti-serizure drugs I am not sure which joker thought this has to be a news piece because the whole country is now panicking on this absolutely nonsense alert on one of the safest drug out there on a side effect that is literally not reported in published literature from India. DRESS syndrome is a well known BUT extremely extremely rare (yes I used two extremely's) adverse event associated with painkillers such as mefenamic acid The most common drugs that lead to DRESS syndrome are anti-seizure medications (almost 50% cases reported world-wide) such as carbamazepine, phenytoin and phenobarbitone, antibiotic such as minocycline and the drug given for gout, called allopurinol. Carbamazepine anti-seizure drug has been reported to be implicated in most DRESS cases world over - 27% of all reported cases! ncbi.nlm.nih.gov/pmc/articles/P… NSAID causing DRESS syndrome reported world-wide makes hardly 3-5% of cases (WORLDWIDE!) - of this, indomethacin (a painkiller that is seldom used nowadays) is most commonly implicated, not mefenamic acid. ncbi.nlm.nih.gov/pmc/articles/P… Fact: Published reports of mefenamic acid causing DRESS syndrome from Asia - ZERO. Published reports of NSAID group of drugs overall causing DRESS syndrome in India - ZERO. Published reports of the NSAID drug mefenamic acid drug causing DRESS syndrome in India - ZERO. pubmed.ncbi.nlm.nih.gov/?term=mefenami… & pubmed.ncbi.nlm.nih.gov/?term=mefenami… More facts: Published reports of Ayurvedic drugs with heavy metal contamination - LITERALLY >100s OF CASES Published reports of Ayurvedic drugs with Lead contamination - LITERALLY >50 OF CASES Published reports of Ayurvedic Giloy herb causing liver injury and liver failure in India >250 CASES. Published reports of Ayurvedic Ashwagandha causing liver injury and liver failure in India ~ 10 CASES. Where is the safety alert on these? I have no idea what the drug regulation system in India has become. It has become the joke of the century. Looks like a one-trick pony favoring traditional medicine over scientific medicine. Shame!







Bestow all the fix pay employees with full pay and other benefits they deserve on the international equal pay day. #RemoveFixPay #WeWantEqualPay #InternationalEqualPayDay @CMOGuj @Bhupendrapbjp @JanakThakkar_ @devanshijoshi71 @Vivekdoza @VtvGujarati @shaktisinhgohil



1/2 Our stressed-out PhD scholars deserve a long-overdue increase in their stipends. The revision was due in 2022 after an already delayed raise in 2019. How can they meet their daily needs & undertake research amid rising inflation? @IndiaDST indiatoday.in/education-toda…







