Paul

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Paul

Paul

@paul_lomas

Notts County . I am a confirmed atheist. #VamosOrlando #DaleMiAmor Part time paint seller for @Exit23Games #T1d

Katılım Ağustos 2011
2.2K Takip Edilen641 Takipçiler
Paul
Paul@paul_lomas·
Didn’t get many pictures today. Saw Matty on his way in. What an incredible away day. You pies @Official_NCFC 🖤🤍
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Notts County FC
Notts County FC@Official_NCFC·
Top support 👏
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kelly
kelly@kellyJaneJames·
@paul_lomas @Official_NCFC Great result. I was in the nest watching it amazing atmosphere. Joshua was there though 🖤🤍🖤🤍
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Adam Hassell
Adam Hassell@adam_hassell·
The scene is set at Chesterfield. No one has been involved in more play-off campaigns in the top five divisions than #Notts County, yet somehow the Magpies are today looking to win an away play-off match for the first time. Full comms on BBC Radio Nottingham @bbcrns from 5!
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Paul
Paul@paul_lomas·
On the way to Chesterfield. You pies. Definitely not nervous. 🖤🤍
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What’s Racing About Podcast
@NoContextBrits No Mr Brightside ......EVER!! Because it's a pile of steaming nothingness Yank wannabe 'nearly-music' by a bunch of Mormons that don't get it, didn't get it and never would get it ......just say 'DICK' you bunch of fucking try-harder bedwetters. ....cos I'm Norman Whiteside
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Paul
Paul@paul_lomas·
@EddieBurfi Spend ages deflecting and bemoaning criticism and goes on to call the greens antisemitic.
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Eddie Burfi
Eddie Burfi@EddieBurfi·
Richard Tice repeatedly refusing to condemn remarks from a Reform UK councillor who said ‘people should melt Nigerians to fill in pot holes.’ 😳 They are showing us exactly who they are. #BBCLauraK
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andy legg
andy legg@leggy191·
All the best Notts county today in the playoffs c/mon you pies
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No Context Brits
No Context Brits@NoContextBrits·
How did it end up like this?
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Paul
Paul@paul_lomas·
@Rainmaker1973 i've had Type 1 for nearly 30 years and i'm sick of it, this cannot and probably will not come fast enough
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Massimo
Massimo@Rainmaker1973·
Type 1 diabetes was cured in mice – permanently. In a groundbreaking study, scientists successfully halted type 1 diabetes in mice by co-transplanting blood-forming stem cells and insulin-producing islet cells from a donor. This created a mixed (chimeric) immune system — part donor, part recipient — that tolerated the new islet cells and prevented further autoimmune attacks on the pancreas. Type 1 diabetes occurs when the immune system mistakenly destroys the body’s own insulin-producing beta cells in the pancreatic islets. The new approach essentially “resets” this faulty immune response. - Mice first received low-dose radiation and targeted antibodies to mildly suppress (but not wipe out) their immune system. - They were then given donor hematopoietic stem cells (to rebuild a tolerant immune system) and healthy donor pancreatic islets (to restore insulin production). - A short course of an existing immunosuppressive drug was added to bridge the process. The results were striking: no rejection of the transplanted cells, no graft-versus-host disease, and complete prevention or reversal of diabetes. In one group, all 19 treated mice remained diabetes-free; in another, all 9 mice with established diabetes were fully cured. Importantly, nearly every component of this protocol — the antibodies, low-dose radiation, and immunosuppressive drugs — is already approved and routinely used in human medicine. This dramatically shortens the path to clinical trials in people. Challenges remain, particularly the limited supply of human islet cells and the need for donor-recipient matching. However, researchers are actively developing lab-grown islets and techniques to generate larger quantities of compatible tissue. If proven safe and effective in humans, this strategy could not only cure type 1 diabetes but also revolutionize treatment for other autoimmune conditions (such as lupus and rheumatoid arthritis) and improve outcomes in organ transplantation. ["Curing autoimmune diabetes in mice with islet and hematopoietic cell transplantation after CD117 antibody-based conditioning." Journal of Clinical Investigation, 2025]
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Josh Seward
Josh Seward@josh_seward·
🎟️✅ Easy that. Managed to bag 6 despite not being to a town away game since Old Trafford in ‘97. Up the crooked spires.
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Larry the Cat
Larry the Cat@Number10cat·
No @BBCNews - you can't send out a breaking news alert to millions of people across the UK that begins "Sir David Attenborough..." the day before his 100th birthday. The entire country just took a sharp intake of breath.
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Paul
Paul@paul_lomas·
@Ben_Bradley_32 As my former representative you lied repeatedly maybe you should stay out of this
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Ben Bradley
Ben Bradley@Ben_Bradley_32·
Angela Rayner openly lying to school children about Nigel Farage and Reform - even suggesting that children would die if Reform were in government - based on a fake policy that Nigel and many others in Reform have consistently said is untrue. This is really, really bad. Using children for political points. Lying to them about your opposition. Scaring them with falsehoods, and posting it online yourself because you're somehow proud of it! This woman could be PM in a few weeks 🤡
English Fox@itsenglishfox

I’m not a fan of Farage but this is absolutely shameful and dishonest from @AngelaRayner x.com/AngelaRayner/s…

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Major League Soccer
What's better than scoring a hat trick? Scoring a hat trick that leads to a comeback win against a rival. 😤
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