Peter Kennel

/4 Take-home: ARNI did not significantly preserve LVEF%, but prevented GLS decline and blunted biomarker evidence of chronic myocardial injury/stress. 👉 Suggests potential role in CTRCD prevention. Larger, outcome-driven RCTs needed. #OriginalResearch #CardioOnc #HF

/3 Findings (18 mo): - Primary endpoint (CMR LVEF%): Placebo –2.2% vs ARNI –1.1%;Δ+1.1%(NS,p=0.16) - Secondary endpoints: - GLS: preserved with ARNI, declined with placebo - Biomarkers: attenuated rise in troponin I & NT-proBNP with ARNI - Safety: well tolerated, no excess SAEs

#ESC #SimPub on PRADA II Trial: Can sacubitril/valsartan prevent anthracycline ± trastuzumab–related cardiotoxicity in early breast cancer? 138 women randomized, ARNI vs placebo, followed 18 months with CMR, echo GLS, troponins, NT-proBNP. 🧵Thread summarizing key findings:

Excited to share new research from our laboratory led by @xhliao1 and @peterjkennel on Epigenetics of Heart Failure, Recovery with LVAD, and discovery of LINC00881 as a novel target. Grateful to our collaborators ReillyLab, @NirUrielMD, @GVNLab, @SMarxLab. insight.jci.org/articles/view/…

Another year in the wraps! The latest generation of Columbia trained cardiologists with program leadership🩺🫀 Congrats to our graduating fellows! And to our incoming fellows, welcome to the Columbia Cardiology family!

Our new review in @JAMACardio on remote cardiac monitoring devices in HF. Stellar work by @peterjkennel @BurkhoffMd @gtsayer. Options for precision-based management of chronic HF are only growing @NYPCUCVI @nyphospital

Just published...Insights into Impella 5.5. ColumbiaCardio Case Series. @peterjkennel @heidilumish @Justin_FriedMD @ajaykirtane @HirooTakayamaMD @YoshifumiNaka @NirUrielMD @AmirMasoumiMD @abiomedimpella @gtsayer onlinelibrary.wiley.com/doi/10.1002/eh…

Thrilled to share new chapter of regenerative medicine: repurposing distal gut to breathe! Mammalian enteral ventilation ameliorates respiratory failure cell.com/med/fulltext/S…

Metabolomics on healthy and failing human hearts reveal a comprehensive and quantitative picture of human #cardiac fuel use. Paper from Zolt Arany and colleagues, #NatMetabPicks science.sciencemag.org/content/370/65…

Check out descriptions from @ColumbiaCardio fellows and faculty about the fellowship experience, core rotations, and all that goes into our unique cardiology training program! The Fellowship Experience youtu.be/bnycUPB4Au8

How can we encapsulate Columbia Cardiology in one word? Watch fellows and faculty discuss what they love about Columbia! ⬇️ Columbia Cardiology Testimonials youtu.be/z9Sr5sCMwTM

Here marks the first post from @ColumbiaCardio - the official account of the @Columbia / @nyphospital Division of Cardiology. Follow us and stay tuned for the latest developments and updates on our faculty and fellows!

Just 3 former @WeillCornell chief residents. #InGoodCompany #TonyFauci @cornellcmr @NIH

Impairment of Myocardial Glutamine Homeostasis Induced By Suppression of the Amino Acid Carrier SLC1A5 in Failing Myocardium | Circulation: Heart Failure ahajournals.org/doi/full/10.11…

Grateful for such thoughtful, fun and kind co-first year fellows and the opportunity to spend #AHA19 together. Thanks to @NYPCUCVI @ColumbiaMed @nyphospital for making it happen.

I want to be in the meeting where this idea was proposed

David E. Rogers Memorial Research Award Finalists Maria Pabon (congrats on the 1st prize!), Yasin Hussain, @samyamshon and I, thank you @WeillCornell @cornellcmr

Exosomal profiling in cardiac allograft rejection: Best basic science article in 2018 jhltonline.org/article/S1053-…