Mgoes (bio/acc 🤖💉)@m_goes_distance
biotech has got insane velocity in 2026
here's what just crossed the line from mice to humans:
- Life Biosciences enrolled first humans in epigenetic reprogramming trial - Sinclair's life work, in people, now
- Azalea (Doudna's lab) first human success with in vivo CAR-T, the engineering happens inside your body, no extraction required
- baby KJ, first personalized in-body CRISPR edit ever, 7 months from diagnosis to functional cure
- Kyverna's CAR-T put lupus into drug-free remission, filing for first ever autoimmune CAR-T approval
- pig kidneys with 69 gene edits kept a man off dialysis 271 days, FDA cleared 30-patient trial
- Retro Bio (Sam Altman-backed) dosed first human with RTR242, targets Alzheimer's and aging at the cellular root
- GLP-1s confirmed as first true longevity drugs in humans, reduces mortality, protects the brain, slows kidney aging, all in the same molecule
- Insilico's AI-designed drug hit Phase II for fibrosis with positive efficacy, first AI-discovered molecule to work in humans
- Compass crushed Phase III for psilocybin in treatment-resistant depression, 50 years of regulatory hell, done
- rapamycin PEARL trial showed measurable healthspan improvements, the longevity drug finally has human data
slowly, then sudden
bio/acc
