Pranav Lalgudi

A special shoutout here to @plalgudi11, seen here helping to spot *the grids* almost four years ago to the day at MIT!

Thrilled to see this out and grateful to have had the chance to play a part in it 🫡

Nature research paper: Mouse lemur cell atlas informs primate genes, physiology and disease go.nature.com/3Hd7fDj

Today in @Nature we report a systematic strategy to activate & identify gene sets in plants. We identify 8 new genes from the yew tree's Taxol biosynthetic pathway, enabling us to engineer tobacco with 17- & 20-gene pathways to Taxol precursors baccatin III and dBz-deoxy-Taxol. a thread 1/x.. nature.com/articles/s4158… With amazing coauthors @Sattely_lab @ctliu629 @fordycelab @Stanford_ChEMH @StanfordEng

It is finally out! I am incredibly proud to share that my work has officially been published in Cell @CellCellPress! This work was a product of years of dedication and countless hours of research in the labs of Joanna Wysocka and @JaroszLab @StanfordMed cell.com/cell/fulltext/…

In this week’s @Nature, we report that nutrients do not activate mTORC1 through degradation of GATOR1 component DEPDC5. Other molecular events signal the presence of amino acids to this essential growth pathway! nature.com/articles/s4158…

Today we report that an engineered skin bacterium, swabbed gently on the head of a mouse, can unleash a potent antibody response against a pathogen. Could lead to topical vaccines that are applied in a cream. @DjenetBousbaine led the charge... @Nature 1/55

Out in @PNASNews now, we find that the Rag-Ragulator heptamer anchors the GATOR supercomplex to the lysosome. Our results highlight the complex role the Rags play in regulating mTORC1 activation and lysosomal homeostasis (1/2)

How to pick a problem. Today in @CellCellPress. 1/53 cell.com/cell/fulltext/…

@XinGu0317 @ScienceMagazine Congrats!! 🍾

Over the moon about my postdoc work ⁦@ScienceMagazine⁩ ! Ever wonder about how mammalian cells selectively degrade unwanted nuclear proteins without involving ubiquitination? Check out our paper on a non-canonical protein degradation mechanism! science.org/doi/10.1126/sc…

Super excited to share this collaborative work @Nature that focuses on the roles of Sestrin-mTORC1 in organismal dietary leucine response. So much fun working with @PJouandin from @PerrimonLab. Thank all co-authors for their very valuable contributions.nature.com/articles/s4158…

Excited and grateful to share this with the world! Our structure of the mysterious GATOR2 complex sheds light on the ways that mTORC1 receives and integrates nutrient signals. Thank you to everyone who contributed to this work! 🐊🐊

RING HIIM

@United4You1 @davidjmlee @shreyas899

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Welcome 𝗵𝗼𝗺𝗲, @Cristiano 🔴 #MUFC | #Ronaldo