Max Valenstein, MD, PhD

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Max Valenstein, MD, PhD

Max Valenstein, MD, PhD

@mlvalenstein

@MGHMedRes Stanbury PSP @MGHMedicine | Alum @HarvardMITMDPhD @HarvardMed @MIT_HST @MITBiology @Yale @YaleMBB

Katılım Kasım 2014
168 Takip Edilen240 Takipçiler
Max Valenstein, MD, PhD
Max Valenstein, MD, PhD@mlvalenstein·
A special shoutout here to @plalgudi11, seen here helping to spot *the grids* almost four years ago to the day at MIT!
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Max Valenstein, MD, PhD
Max Valenstein, MD, PhD@mlvalenstein·
Please check out the beautiful videos, rendered by Kacper, that bring these proteins to life!
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Max Valenstein, MD, PhD
Max Valenstein, MD, PhD@mlvalenstein·
Grateful to have contributed a (very) small part to this fantastic work. Congratulations to @jason_yang0, @chivukula_raghu, et al!
Raghu Chivukula, MD PhD 🫁🧬🧠@chivukula_raghu

This work was led by @jason_yang0 (now @BrunetLab) and aided by a talented and hardworking team: Forrest Xu, David Ziehr, @DrMartyTaylor @mlvalenstein @genfren Jack Bush, Kate Rutter, Igor Stevanovski, @CharlieYShi Mahesh Kesavan, @RMouroPinto @IDeveson David Bartel @DMSabatini

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Dana-Farber News
Dana-Farber News@DanaFarberNews·
A new study in @CellPressNews led by @DanaFarber’s @XinGu0317 highlights midnolin as a key regulatory component of proteostasis in plasma cells and suggests that restoring or enhancing this pathway could represent a novel therapeutic avenue in myeloma treatment. Read more: bit.ly/4l8Zuwu
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Max Valenstein, MD, PhD
Max Valenstein, MD, PhD@mlvalenstein·
In this week’s @Nature, we report that nutrients do not activate mTORC1 through degradation of GATOR1 component DEPDC5. Other molecular events signal the presence of amino acids to this essential growth pathway! nature.com/articles/s4158…
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Max Valenstein, MD, PhD
Max Valenstein, MD, PhD@mlvalenstein·
Out in @PNASNews now, we find that the Rag-Ragulator heptamer anchors the GATOR supercomplex to the lysosome. Our results highlight the complex role the Rags play in regulating mTORC1 activation and lysosomal homeostasis (1/2)
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Max Valenstein, MD, PhD retweetledi
Jose Florez
Jose Florez@JoseFlorezMDPhD·
The @mghmedres Stanbury program attracts and trains top physician-scientists. At this year's summer retreat, @MGHMedicine family member @RWalensky shared her insights on matters relevant to her tenure as @CDCgov Director.
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Xin Gu
Xin Gu@XinGu0317·
I'm thrilled to join @DFCI_CancerBio and @HarvardCellBio as a tenure track assistant professor Sept 2024! The Gu lab elucidates mechanisms underlying cellular homeostasis, with our initial effort on nuclear protein turnover by the ubiquitin-independent midnolin-proteasome pathway
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Xin Gu
Xin Gu@XinGu0317·
Over the moon about my postdoc work ⁦@ScienceMagazine⁩ ! Ever wonder about how mammalian cells selectively degrade unwanted nuclear proteins without involving ubiquitination? Check out our paper on a non-canonical protein degradation mechanism! science.org/doi/10.1126/sc…
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Jan-Philipp Quast
Jan-Philipp Quast@QuastJP·
Big thanks to @bradyajohnston for a great first #Blender workshop day! I learned a lot and could even already render a very simple but pretty animation! 🤩
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Xin Gu
Xin Gu@XinGu0317·
Super excited to share this collaborative work @Nature that focuses on the roles of Sestrin-mTORC1 in organismal dietary leucine response. So much fun working with @PJouandin from @PerrimonLab. Thank all co-authors for their very valuable contributions.nature.com/articles/s4158…
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Keşfet

@DrMartyTaylor @chivukula_raghu @plalgudi11 @jason_yang0 @DanaFarberNews @CellPressNews @DanaFarber @XinGu0317