yves desjardins

You're using Claude wrong. Here's my (exact) setup before I even prompt: Step 1. Download Claude and open Cowork → Go to Claude. com/ download. → Install the desktop app. → Click the Cowork tab at the top. → You need a Pro plan ($20/mo). Worth it. → Full guide here: lnkd.in/dVDent-3 --- Step 2. Select the right model (don't skip this) → Click the model dropdown. → Select "Opus 4.6." → Turn on "Extended Thinking." → Never change these. Wrong model = bad output. --- Step 3. Build your folder → Create one master folder on your computer. → Inside it, create 4 subfolders: ✦ ABOUT ME - who you are + how you write ✦ PROJECTS - one subfolder per live project ✦ TEMPLATES - your best work as structures ✦ OUTPUTS - where Claude saves finished files → Upload this folder. That's how it reads you. --- Step 4. Create 3 context files inside ABOUT ME → These replace prompting. This is the setup. → Create them as .md files. Plain text, saved as .md ✦ about-me.md - what you do day-to-day. ✦ my-voice.md - tone, phrases you hate, 3 example ✦ my-rules.md - ask first, show a plan, get approval OR Simply download my .md files here: how-to-ai.guide Subscribe for free. Open my welcome email. Hit the automatic reply button inside. --- Step 5. Set Global Instructions (once, forever) Go to Settings → Cowork → Edit Global Instructions. → Paste: "I'm [Name], [Role]. Read my files before every task. Ask clarifying questions before executing. Show a plan before acting. Never delete without my approval." → You set this once. It runs every session. → Your prompts can now be 10 words long. --- Before your next Cowork session, check these: 1. Am I in Cowork (not Chat)? 2. Is Opus 4.6 + Extended Thinking on? 3. Did I point it to my folder with context files? Set these first. Then prompt. Top 1% of Claude users do this. Now you can too.

Claude Code will fundamentally change the nature of academic research. But most academics don't know how to use it. Here's how to get started on Claude Code (even if you've never coded). Claude Code for Academics 101:

How to convert your rough notes into a complete paper in minutes? 1. Go to gatsbi.com and upload your notes 2. Gatsbi will first give a summary of your notes 3. You can verify it and press enter 4. Gatsbi will convert it into a polished research paper. #PhD

🚨BREAKING: The "Cursor for scientific research" just dropped and it runs entirely inside Claude Code. It's called claude-scientific-skills and it gives Claude 140 ready-to-use scientific skills from a single plugin install. No API doc hunting. No library configuration. No duct-taped research pipelines. It's powered by 28+ live scientific databases wired directly into Claude. → Describe your research goal in plain English → Claude finds the right skill automatically → Full pipeline runs: data retrieval → analysis → publication-ready output → Works across biology, chemistry, medicine, ML, and clinical research All running inside Claude Code. Zero manual setup. But it's not just a prompt library. It's a full AI research lab: → Drug discovery: ChEMBL → RDKit → DiffDock → lead optimization in one prompt → Genomics: 10X data → Scanpy → GRN inference → pathway enrichment → Clinical: VCF → ClinVar → pharmacogenomics → patient report → Multi-omics: RNA-seq + proteomics + metabolomics integrated automatically 7.8k stars. 924 forks. MIT Licensed. MacOS, Windows, Linux works everywhere Claude Code runs. This is the moment AI stops being a chat tool and becomes an actual research partner. Link in the first comment 👇

🇩🇪🎙️🎶 Voici Anna Maria Hefele, chanteuse harmonique allemande. Elle est une des rares personnes maîtrisant parfaitement l'art de chanter deux notes simultanément. Le résultat est surprenant ! 😳

Here is an nice follow-up article stressing the significance of the discovery presented in our recent paper in Nature Comm. by Rodriguez-Daza et al. Congrats #carolinaRodriguez-Daza, #WilhemdeVos Akkermansia Uses Polyphenols to Boost Iron Uptake scienmag.com/akkermansia-us…

Un autre échange délicieux de @mbockcote, cette fois-ci avec le libertarien Jonathan Hamel, qui n’en manque jamais une pour nous étaler toute la vacuité intellectuelle dont il est capable. La fin: du bonbon ! 😀

🚨ECONOMIC EARTHQUAKE: US Supreme Court Signals They Are Set To Overturn Trump's America 1st Tariff Policies! In This Powerful Must-Watch Report, Alex Jones Destroys Chief Justice John Roberts' Arguments & Issues A Dire Warning!

Congrats to Carolina Rodriguez-Daza for two great achiements. First, she is the happy mother of Agatha. Second, her article on the effect of cranberry procyanidins on the proliferation of Akkermansia muciniphila is now published in Nature Comm. (nature.com/articles/s4146…). Our findings reveal a previously unrecognized iron acquisition strategy in this bacterium, allowing it to utilize PAC-bound iron. This mechanism accounts for its expansion in response to PACs and its ability to outcompete enterobacteria. These results offer valuable mechanistic insight into the role of polyphenols in modulating microbial physiology and ecological interactions.

Félicitations à Carolina Rodriguez-Daza pour deux grandes réalisations ! D’abord, elle est l’heureuse maman de la petite Agatha. Elle signe également une publication dans Nature Communications portant sur l’effet des procyanidines de canneberge sur la prolifération d’Akkermansia muciniphila. (nature.com/articles/s4146…). Nous y montrons qu’Akkermansia muciniphila est capable d’acquérir le fer grâce à un mécanisme unique lui permettant de capter le fer complexé aux PAC. Cette stratégie nutritionnelle explique non seulement sa prolifération en présence de PAC, mais aussi sa capacité à entrer en compétition avec les entérobactéries. Une étude mécanistique élégante qui met en lumière le rôle des polyphénols comme déterminants majeurs de la physiologie et de l’écologie microbiennes.

BREAKING: After the release of an ad that caused Trump's tantrum ending trade talks with Canada, the original video of Ronald Reagan slamming tariffs has resurfaced. He called the new ad "fake." The original destroys Trump on tariffs. Share this widely.

BREAKING: trump is having a temper tantrum, ending ALL trade negotiations with Canada. He's butthurt that they aired an ad of President Reagan that shows how dumb trump's tariffs are. It's VERY effective. Be a shame if it went viral. 🇺🇲🇨🇦

Attaque du Canada sur la clause dérogatoire et laïcité. Ce discours d'Yves-Francois Blanchet est à mon sens le meilleur discours de sa part que j'ai entendu! Il saisit l'importance historique actuelle. Écoutez ça! #polqc #polcan

A lire. Une oraison funèbre de la "troisième voie" et des naufrageurs qui nous ont conduit dans le mur en prétextant le "pragmatisme". action-nationale.qc.ca/l-effondrement…

Le gars qu’il faut pour Arthabaska!⚜️ #polqc

First day with the new Blackmagic 180 camera. I’ve been doing immersive for over 10 years. This is the camera I’ve been waiting for. The workflow is light years better than anything I’ve used in the past. Thanks to the band Silk Road for the music and Swell for the space.

🎥 À voir absolument. Un véritable bijou. L’histoire, l’histoire, l’histoire. ✨ Il faut tomber amoureux de toute notre histoire : ses grandeurs, ses blessures, ses espoirs. Chaque mot, chaque geste, chaque silence compte. ❤️ Prenez 16 minutes pour vibrer avec ce moment inoubliable : France, Québec, De Gaulle.

We can’t condemn Trump but still give him a seat at the table, it’s mixed messaging …. Enough is ENOUGH !!!! For the sake of humanity, we MUST stop including Trump in ANYTHiNG‼️

RETWEET if you stand with California Governor Gavin Newsom against Donald Trump!