Ajay Sethi

1.1K posts

Ajay Sethi

Ajay Sethi

@sethi_ajay

Startups. Value creation. Strategy. Products. Growth. Make in India. Data-driven Meditation. Spirituality. Own opinions. @accel_india

Bangalore Katılım Haziran 2009
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Anish Moonka
Anish Moonka@anishmoonka·
Before it took off, the bird ate parts of its own liver, kidneys, and gut. That was the only way to be light enough to fly. Then it flew 8,425 miles from Alaska to Australia, in 11 days, without eating, drinking, or landing once. The bird is called B6. It's a bar-tailed godwit, four months old, weighing about as much as a can of beans. In October 2022, scientists at the US Geological Survey tracked its flight from Alaska all the way to Tasmania. The trip took 11 days and 1 hour. It is still the longest non-stop flight of any animal on Earth. For two weeks before takeoff, godwits eat until they almost double in weight. Fat ends up being 55% of their body, more than any bird ever measured. Then they shrink their own insides. About a quarter of their liver, kidneys, stomach, and intestines gets broken down and reused for fuel, making room for the extra fat and cutting weight. Their heart and wing muscles grow bigger at the same time. They never drink along the way. The water they need comes out of burning fat, the same reaction their muscles use for energy. They also never really sleep. B6 flapped its wings for 264 straight hours, cruising around 35 miles per hour with help from storm tailwinds. By the time it landed, it had lost almost half its body weight. The shrunken organs grew back over the following weeks. Scientists still cannot explain the navigation. B6 had never made this flight before. Adult godwits leave Alaska weeks earlier, so young birds fly alone with nobody to follow. How a four-month-old bird finds its way across 8,425 miles of open ocean to a place it has never seen is still an open question. About 100,000 bar-tailed godwits leave Alaska every fall. Most of them land in New Zealand or Australia 10 or 11 days later, having eaten parts of themselves to get there.
All day Astronomy@forallcurious

#BREAKING🚨: This 5-month-old just flew 8,425 miles from Alaska to Australia with no food, no water and zero stops for 11 days straight

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Sama Hoole
Sama Hoole@SamaHoole·
India ran the most important cardiovascular study of the 20th century by accident, and then immediately forgot about it. In 1967, Dr. S.L. Malhotra published a study in the British Heart Journal examining heart disease rates among 1.5 million Indian railway employees. The population was extraordinarily useful for research purposes: same employer, same healthcare access, comparable income and working conditions, spread across the entire country. The only meaningful variable was geography. Which meant diet. North Indian railway workers: Punjab, Rajasthan, UP, ate a diet built around ghee and dairy fat. They consumed up to 19 times more fat than their southern counterparts. The fat was primarily saturated: clarified butter, milk fat, the short-chain saturated fatty acids that Ancel Keys had recently been telling the Western world were arterial death. South Indian railway workers ate a diet based on rice, sambar, and seed oils: groundnut oil and sesame oil, primarily. They ate considerably less fat overall. By the standards of dietary advice being formulated in the 1960s, they should have been the healthy ones. Heart disease mortality in South India: 135 per 100,000. Heart disease mortality in North India: 20 per 100,000. Seven times higher in the population eating seed oils. Among railway sweepers specifically, the lowest-paid, most physically active workers, the gap was even wider. Heart disease was fifteen times more common in the South Indian sweeper population than in the North Indian sweeper population. Malhotra controlled for everything he could reach: smoking, where Northerners actually smoked more. Activity levels, where the relationship was inconsistent. Socioeconomic status, where executives died more often than sweepers regardless of region. He found no variable that explained the gap except the type of fat in the diet. He published the data. In a peer-reviewed journal. In 1967. The study was cited periodically, acknowledged as methodologically interesting, and then set aside. The decade in which Malhotra published was the decade in which Ancel Keys's fat hypothesis was being converted into policy. The American Heart Association was issuing guidance recommending polyunsaturated vegetable oils as replacements for saturated animal fats. The food industry was producing seed oils at industrial scale. The infrastructure of seed oil promotion was being built, expensively and with great institutional momentum. A study showing that populations eating animal fat had a fraction of the heart disease of populations eating seed oils was not, in that context, a study that anyone particularly wanted to follow up. Nobody followed up. Almost sixty years later, the finding stands unrefuted in the literature. It is not in the dietary guidelines.
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Parimal
Parimal@Fintech03·
While Diophantus was struggling with his single symbol in Alexandria, Indian mathematicians most notably Brahmagupta (c. 598 CE) & the authors of the Bakhshali Manuscript (which carbon dating now places as early as the 3rd century CE) were taking a completely different, & arguably superior, path. In the Bakhshali Manuscript, the unknown was not a letter; it was a large dot (•). This dot was called shunya, meaning void/empty place. This is the exact same symbol they used for Zero. In Ancient India, Zero & The Unknown Variable were essentially the same concept; an empty space waiting to be filled. The "Color-Coded" Variables (Varna): This is where India leaped ahead of Diophantus. Cos the dot could get confusing if we had multiple unknowns, Indian mathematicians invented Varna-Samikarana (Eqn by Colors). If a problem had multiple unknowns (what we call x, y, z), they assigned them names of colors: Kalaka (Black): our x Nilaka (Blue): our y Pitaka (Yellow): our z While Diophantus was stuck with 1 stigma, Indian mathematicians were doing multivariable calculus by basically painting their eqns. When these Indian texts were later translated into Arabic (& eventually reached Europe), the color names were dropped, but the idea of using different letters for different unknowns stuck.
The Math Flow@TheMathFlow

Diophantus of Alexandria (c. 250 AD), an ancient Greek mathematician often called the "father of algebra," was the very first person known to use a dedicated symbol for an unknown quantity in equations, the direct ancestor of how we use “x” today. In his famous work Arithmetica, he used a symbol that looked similar to the Greek letter stigma (ϛ) to represent the unknown, which he simply called arithmos (meaning "the number"). Before this, mathematical problems were written out entirely in words.

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Kausik Gangopadhyay
Kausik Gangopadhyay@kausikgy·
Did Christianity originate from a group of Mahayana Buddhist monks? This oft-repeated hypothesis came to Swami Vivekananda in a dream and he was impressed by it. [1] @JoeAgneya's The Will of the Tathagatha is a superlative book on this theme. This book integrates deep scholarly understanding of the author with his superb investigation to make an unmissable work. The book is so rich that even a university-level course is insufficient to comprehend it fully. The claim is that some Buddhist monks at Alexandria and versed in Greek created the core of Christianity. a. Why was NT written in Greek leaving aside Aramaic (the language of Jesus and his disciples) and Latin (the official language of the Roman empire)? b. The manuscripts of NT borrowed from an unknown source Q that cannot be anything but the Buddhist cannons. c. Each of the significant things of NT has a parallel from the life of the Buddha and the Jataka tales, such as, The Virgin Birth, The Great Star, Wild animals adoring Jesus, Giving life back to sparrows, The Parables of Jesus, Multiplication of Food by Jesus. d. The tales of Jesus and Buddha are identical too: Fasting/ penance => Temptation by the Devil/ Mara => Wandering within kingdom =>Visitation by followers =>Arrival at Galille Lake/ Ganga river => Gathering early disciples => Sermon on a "Mount". e. The complete reversal of the ethics of the Old Testament and the monastic tradition came from Buddhism, brick by brick, drop by drop. Could all these be a coincidence? After reading the book, it would seem that they are as much coincidence as it is possible for a monkey to randomly hit the keys of a typewriter and produce a Shakespearean sonnet as the output! I am too overwhelmed by the book even after reading it twice to even point out any weakness. The book could be purchased at amazon.in/WILL-TATH%C4%8… #BookReview #24 Last time, I discussed Termites: How the Left is Destroying the World through Subversion by Abhijit Joag. References 1. grok.com/share/c2hhcmQt…
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Amazing Physics
Amazing Physics@amazing_physics·
A cosmic ocean exists where no human has ever sailed. Astronomers have detected a water cloud 12 billion light-years away, holding an astonishing 140 trillion times the water in all of Earth’s oceans combined. It is a discovery so vast that it stretches the imagination, challenging our sense of scale and reminding us how tiny our world truly is. This cloud, seen in the early universe, hints at a time when galaxies were forming and black holes were already shaping their surroundings. The sheer quantity of water suggests that the ingredients for life are not confined to our solar system — they exist in unimaginable abundance, waiting silently in the cosmos. Scientists are stunned not only by the scale but also by the implications. Water, essential to life as we know it, appears in massive quantities even in the distant past, meaning that the universe may have been capable of supporting habitable conditions far earlier than previously imagined. Every observation opens a new window into the chemistry of the early cosmos. Looking at such a cloud evokes both wonder and humility. The enormity of space, the age of light reaching our telescopes, and the invisible forces shaping galaxies remind us that discovery often comes cloaked in awe. This water cloud is a monument to the mysteries that remain, whispering of worlds and possibilities we have yet to encounter. And so we are left with a quiet reflection: billions of light-years away, water flows in quantities beyond comprehension, reminding us that the universe is filled with secrets that continue to stretch the limits of human curiosity.
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Dr.Sayajirao Gaikwad
Dr.Sayajirao Gaikwad@DietDrsayajirao·
🫀 Key Cardiac Risk Markers You Shouldn’t Ignore Heart attacks in 20s & 30s are becoming frighteningly common. Fit on the outside ≠ Healthy on the inside. Here’s how to investigate early & prevent silent cardiac risk 👇 🔴 1. Lipid Profile is just the beginning Check more than just total cholesterol. ✅ LDL (bad cholesterol) ✅ HDL (good cholesterol) ✅ Triglycerides (TG) ✅ VLDL 🔍 Ideal: • TG < 100 • HDL > 50 • LDL < 100 • TG/HDL ratio < 2 🔴 2. ApoB & ApoA1 – Better than LDL 🔸ApoB = Number of artery-clogging particles 🔸ApoA1 = Protective particles ✅ Ideal ApoB < 90 ✅ ApoB/ApoA1 Ratio < 0.6 This is a stronger predictor of heart disease than LDL alone. 🔴 3. Lp(a) – The silent genetic risk 🔸Not tested in basic reports 🔸Genetically inherited 🔸Can increase heart attack risk even if other markers are normal ✅ Ideal Lp(a) < 30 mg/dL 📌 Test it once in life—even if you’re young. 🔴 4. hsCRP – Inflammation matters 🔸High-sensitivity C-Reactive Protein 🔸Marker of chronic low-grade inflammation ✅ Ideal < 1.0 mg/L 🔥 Chronic inflammation silently damages arteries. 🔴 5. Homocysteine – B12 & Heart Link 🔸Elevated in B12/folate deficiency 🔸Promotes clotting & damages blood vessels ✅ Ideal < 10 µmol/L 📌 If high, correct B12, folate, B6 levels. 🔴 6. Fasting Insulin & HOMA-IR 🔸Most missed test. Insulin resistance often starts years before diabetes. ✅ Fasting insulin < 6 ✅ HOMA-IR < 1.5 📌 Even with normal sugar, high insulin = silent metabolic risk. 🔴 7. CAC Score (Calcium Score CT) 🔸Non-invasive scan to detect early plaque in coronary arteries 🔸Score 0 = very low risk 🔸Higher scores = hidden artery blockage 📌 Highly recommended if you have family history or are >35 with risk markers. 🧠 Prevention is not just avoiding junk food. It’s about testing early and tracking the real markers of silent cardiac risk. ✅ Don’t wait for chest pain. ✅ Don’t assume fitness = health. ✅ Investigate > Guess ✅ Act early = Live longer #HeartHealth #PreventHeartAttack #MetabolicHealth
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Parimal
Parimal@Fintech03·
Beautiful post, let me add a little further. To the Greeks & later the Renaissance Europeans, a number was a length. They believed, you can draw a line that is 5" long. You cannot draw a line that is -5" long. To a European mathematician like Francis Maseres (as late as 1758), negative numbers darken the very whole doctrines of eqns. He argued that if you have 0 apples, you cannot take away 1. To him, the Indian concept of debt was a linguistic trick, not a mathematical reality. Also, When our numerals system reached Europe, the concept of a negative asset was so threatening to the Church's worldview (which associated nothingness/less than nothing with the Devil) that the City of Florence actually banned our numerals in 1299. Indian mathematicians like Brahmagupta (7th Century) were the 1st to treat numbers as abstract entities rather than things you can touch. They decoupled math from the physical world 1000 yrs before the West did.
Sahana Singh@singhsahana

Why did the Arabs and later the Christians reject negative numbers when the concepts arrived from India? For the Indians who were comfortable with abstract entities, zero and negative numbers did not cause much difficulty. In fact, negative numbers were even used in accounting by the baniya community. For the Arabs, math was more in the realm of geometry; so areas and lengths could only be seen as positive quantities. The original reel was posted by Instagram handle samyuspeaks at instagram.com/reel/DV9CrXVDm…

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Mind Muscle Project
Mind Muscle Project@mindmusclepro·
Lipids simplified! 🧱 Cholesterol – is the material needed for building cell walls, making hormones etc 🛻 Lipoproteins - are basically Trucks transporting Cholesterol along with other things through blood. Depending on size they are of many types. ⛽ Triglycerides – are portable Fuel containers that trucks are carrying along. 🚛 HDL – They are the Recycling Trucks the patrol the roads collecting leftover cholesterol bricks from tissues & arteries, & bringing it back to the liver’s recycling center. HDL- C in your reports is the total leftover bricks in circulation currently. 🚚 LDL – They are the Delivery Trucks that deliver cholesterol bricks from the liver warehouse to construction sites (cells) around the body. LDL- C in your reports is the total unused bricks in circulation currently. 🚨 Lp(a) - Some of these LDL delivery trucks have an extra problem. They are wheel that are extra sticky. 🚛📦 VLDL – They are the Fat Cargo Trucks that mainly transports big boxes of triglycerides (fat) from the liver to storage sites. 🪪♦️ApoB (Apolipoprotein B) - All the main delivery trucks (LDL, Lpa, VLDL..) have a common license plate called ApoB. Counting them gives an idea of the no of trucks on road currently. More means too many cholesterol bricks & extra fuel (Tg) are being transported 🪪🔹ApoA1 (Apolipoprotein A1) - The recycling trucks have a different license plate called ApoA1. If more of these license plates are in action means more cleanup is done. ————— What to Target? ▶️ Total Cholesterol: This number is important, but the break up is more important (usually high means more LDL, VLDL… hence a problem) - Total Cholesterol of around 200 with the right breakup is ideal 🟢 - Too Low & Too High is not ideal 🔴 ▶️ HDL-C: More cleaned up bricks is always better - For men > 40 mg/dL 🟢 - For women > 50 mg/dL 🟢 ▶️ Triglyceride: Lot of portable Fuel being transported means excess energy/calories in the system. - Ideal: < 100 mg/dL 🟢 - High Risk: > 150 mg/dL 🔴 ▶️ VLDL: More of portable fuel trucks is indirectly saying more portable fuel is produced. Hence It is not directly measured, but estimated as 20% of triglycerides - VLDL < 20 mg/dL 🟢 ▶️ LDL-C More unused bricks in circulation is a concern as more delivery trucks can cause a traffic jam (plaque) - Ideal: < 130 mg/dL 🟢 - High Risk: > 160 mg/dL 🔴 ▶️ Lp(a): The more unused bricks in circulation especially inside those trucks with sticky tired is a big cause of concern. But it’s not under your control. - Optimal: < 20 🟢 - SubOptimal: 20- 50🟡 - High risk: 50- 100🟠 - Very high risk > 100🔴 ▶️ ApoB: You want less of trucks with these license plate on the road. They are either carrying unused bricks or extra portable fuel, either way not good. - Optimal: < 80 mg/dL (high risk patients) : < 90 mg/dL (general population) 🟢 - High: > 120 mg/dL 🔴 ▶️ ApoA1: You want more of cleanup trucks with these license plate on the road. - Optimal: < 0.6 🟢 - Acceptable: < 0.8 🟡 - High risk: > 0.9 (men), > 0.8 (women) 🔴 ▶️ ApoB / ApoA1 Ratio: This ratio reflects the balance between Delivery trucks & Clean up trucks. More clean up trucks is always better - Optimal: < 0.6 🟢 - Acceptable: < 0.8 🟡 - High risk: > 0.9 (men), > 0.8 (women) 🔴 ▶️ Triglycerides / HDL Ratio: This ratio reflects the balance between large Cargo trucks specifically & Clean up trucks. Again more clean up trucks & less portable fuel on the road is always better - Excellent: < 1 🟢 - Good: < 2 🟡 - At risk: > 2 🟠 - High risk: > 4 🔴
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Aakash Gupta
Aakash Gupta@aakashgupta·
Everyone is missing what this study actually says to parents. The graph shows two paths to the same destination. The yellow line (early specialization) gets there faster in the early years. The blue line (multi-disciplinary) gets there slower but breaks through to world-class. The key insight: individuals who perform best at a young age are usually not the same people who later reach the world-class level. This came from 34,839 top performers across four domains: Nobel laureates, Olympic medalists, elite chess players, and renowned classical composers. The researchers found three consistent patterns. First, the best kids and the best adults are mostly different people. Second, future world-class performers showed gradual development and weren’t among the best in their age group. Third, they didn’t specialize early but engaged in multiple disciplines. The research team proposes three mechanisms that explain why breadth beats depth. The search-and-match hypothesis suggests that exposure to multiple disciplines increases the likelihood of eventually finding the best personal fit. The enhanced-learning-capital hypothesis proposes that learning in diverse areas strengthens overall learning capacity, making it easier to continue improving later at the highest level within a chosen field. The limited-risks hypothesis argues that engaging in multiple disciplines reduces the chance of setbacks such as burnout, unhealthy work-rest imbalances, loss of motivation, or physical injury. That third one matters enormously. Specialized athletes are 2.25 times more likely to get overuse injuries than multi-sport athletes. The American Academy of Pediatrics, AOSSM, and American Medical Society for Sports Medicine all recommend against early specialization before age 15 for most sports. The lead researcher, Arne Güllich from RPTU University Kaiserslautern-Landau, puts it bluntly: “Don’t specialize in just one discipline too early. Encourage young people by providing opportunities to pursue different areas of interest, and support development in two or three disciplines.” The two or three disciplines don’t need to be related. Language and mathematics. Philosophy and geography. The researchers cite Einstein pursuing physics and violin. The connection between domains seems to build cognitive infrastructure that pure depth cannot replicate. Here’s what makes this uncomfortable for parents. The early specialization path produces visible results faster. Your kid looks better at age 10. They make the travel team. They win the tournament. The graphs cross and diverge later, around peak performance age, when the multi-disciplinary kids start pulling ahead. The entire youth talent ecosystem runs on selecting early performers and accelerating them. Travel leagues, elite academies, showcase tournaments. Every incentive pushes toward specialization. But the research shows this system is optimizing for the wrong metric. It produces great 14-year-olds, not great 24-year-olds. The practical takeaway: let your kid play three sports until at least middle school. Let them quit the piano and try drums. Let them be mediocre at several things instead of great at one thing. The data says this approach produces both more elite performers and fewer burnout casualties. The hardest part is watching other kids pass yours on the yellow line while trusting the blue line catches up.
Brad Stulberg@BStulberg

A massive new study on peak performance included 34,000 international top performers: Nobel laureates, renowned classical music composers, Olympic champs, and the world’s best chess players. It shows early specialization is a trap, and the road to greatness is long and varied.

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Joseph T Noony
Joseph T Noony@JoeAgneya·
Did you know? Jesus is actually called 'Tathāgata' multiple times in the Gospels. Or, Greek puns on the word at least. One example is Matthew 23.10 which calls Jesus 'Kathêgêtês', a rare noun meaning 'Great/Only Teacher'. This was detected by the late multilingual scholar Prof Lindtner.
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Bryan Johnson
Bryan Johnson@bryan_johnson·
First mushroom trip data is out: my brain activity. Dose: 5 g dried Psilocybe cubensis (B+ strain) Containing 24.9 mg psilocybin Psilocybin longevity experiment. What we see in the brain: + brain activity data mirror my subjective experience + strong decrease in my brain’s control center (prefrontal + premotor cortex) + strong increase in sensory, auditory and speech integration + higher entropic brain patterns: open, flexible, less predictable, exploratory + brain network patterns resembling a youthful state vs aged and rigid Matching what I reported experiencing: + “felt like my consciousness was dialed up to 10/10.” + “I felt hyper aware and hyper alive.” + “I experienced sense of touch with awe.” + “my mind was insatiably curious and wanted to deploy its sensors into the world and discover all things.” + “My brain wanted to stare, study and marvel.” + “The flavor exploded in my mouth.” + “...restored my perception to youthful levels, returning them to factory settings and dissolving my aged numbness.” Why this could matter for longevity: + In people aged 65-85, higher happiness was linked to a 22% reduced risk of all-cause mortality over 15 years. + A meta-analysis showed that optimism correlated with a 35% decrease in heart attacks and a 16% decrease in all-cause mortality. + Having a strong purpose in life is associated with a 17% reduction in both heart attacks and all-cause mortality. + In psychedelic medicine, treating depression with ketamine has been shown to reverse biological age by up to 3 years. Together, these findings suggest a plausible mechanism by which psychedelics, including psilocybin, can prolong both health and lifespan by improving mental well-being and rewiring the brain to a more positive, creative, and curious state. My team and I hypothesized that neuroplasticity, the loosening of rigid inhibitory patterns that makes the brain more flexible, creative, and relaxed, and even the subjective psychedelic state itself may be as meaningful for longevity as methylation shifts, senescence reversal, or telomere biology. What’s happening mechanistically Earlier work shows that psilocin (the active metabolite of psilocybin) acts primarily as an agonist at 5-HT₂A serotonin receptors in the cortex. These receptors are especially dense in high-level association and sensory regions, as mapped in a high-resolution PET/MRI atlas of the human serotonin system. When these receptors are activated, brain imaging studies show an induced state of desynchronization, entropy, and neuroplasticity.  This process erodes the rigid brain hierarchy and default mode networks in favor of a brain-wide spontaneous, creative, curious, and child-like state. Kernel Flow data shows the same pattern: The recorded timepoints included: + baseline: directly before session start (not shown) + timepoint 1: 4 hrs after dose (acute phase effects). + timepoint 2: end of the day, before bedtime. + timepoint 3: the following morning. I continue to measure my brain daily. Image notes + The three maps show changes vs. baseline (not absolute activity) + Red = increased connectivity, blue = decreased connectivity vs. my baseline. + The left reference map shows the 5-HT₂A receptor distribution from PET, the main psilocybin target. Time Point 1 - 3 hrs post dose + Reduced connectivity in the prefrontal and premotor cortex, correlating with acute brain desynchronization. + Increased connectivity and hyperintegration between the primary motor and sensory cortex regions. + Enhanced connectivity in the auditory and speech areas of the cortex. + Inhibited connectivity in the medial prefrontal and posterior zones, areas associated with the Default Mode Network (DMN). Subjective experience: + Enhanced sensory vividness and bodily presence: The brain's top-down hierarchy, originating in the pre-frontal cortex, was attenuated. This reduced predictive filtering, leading to a flood of bottom-up sensory information and heightened bodily perception (e.g., a fascination with water and light dynamics in a jar, a restored, primal joy of touch and sensation). + Peak neuroplasticity and cortical entropy: A peak in cortical entropy and neuroplasticity contributed to a feeling of hyperawareness (e.g., heightened sensory perception, feeling "at one with existence," hyper-aware and hyper-alive). + Deeper appreciation of music and uninhibited movement and expression: Sharpened auditory senses and reduced top-down inhibition allowed music to be enjoyed on a profound level. Concomitant functional connectivity in speech-motor and auditory-motor integration areas facilitated uninhibited expression through both speech and movement (a restored, uninhibited, child-like joy of music). + Note: Full ego dissolution was not experienced, which may necessitate a higher dose to achieve more advanced desynchronization of the prefrontal and parietal cortices. Time point 2 - 5 hrs post dose, end of trip + Intensified sensory and motor hyperconnectivity. + Continued increased connectivity in auditory and speech centers, with a relative restoration of connectivity to the speech understanding area. + Partial re-emergence of the prefrontal parietal coupling, while prefrontal context remains partially inhibited. + Partial re-emergence of connectivity in areas related to the default mode network. Subjective Experience + High-order brain networks begin to restabilize, alongside persisting sensory, motor, auditory, and speech hyperconnectivity, suggesting neuroplasticity in action. + The narrative shifts from pure sensation and experience to meaning generation, accompanied by deep philosophical reflection (e.g., reconsidering the meaning of life and one's relationship with mortality in the time of AI, and pondering the future of human evolution). Time point 3 - next morning (afterglow) + Persistence: Patterns from the acute phase continue, including general prefrontal cortex inhibition, ongoing neuronal plasticity, and heightened senses. + Intensified connectivity: Increased connectivity is noted in the speech generation area and the somatic sensory association area. + DMN inhibition: The default mode network remains inhibited. Subjective Experience: + "Afterglow" effect: Characterized by continued sharpened senses, calm clarity, emotional openness, and low inhibitions. For instance, I felt more comfortable expressing uninhibited, self-deprecating humor (i.e. my post making fun of myself about the insane lengths I go for my Don’t Die experiment) + Integration of experience learnings: The heightened activity in the somatic sensory association area aligns with the process of integrating and "making sense" of the raw sensory experience of both the self and the external world. + Enhanced creativity: The intensified connectivity in the speech generation area contributed to the uninhibited bout of creative writing I undertook to report my experience.
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The Paperclip
The Paperclip@Paperclip_In·
Why does sugarcane taste so sweet in India today? India’s sugarcane wasn’t always this sweet. The reason it tastes the way it does today goes back to the stubborn brilliance of one woman who fought prejudice, doubt, and even war. Thread. 1/19
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Joseph T Noony
Joseph T Noony@JoeAgneya·
Granted, it was the Greeks who invented modern historiography. Greece had a Hecataeus who declared "The stories of the Greeks are many and ridiculous". Ancient India did not have anyone to say "The Puranas are full of facts and myths. We need to extract reliable history and chronology from it" But that does not mean India did not preserve history or didn't have historical sense. Ancient Indians have managed to faithfully preserve and transmit a HUGE amount of primary historical data from as far back as the 3rd millennium BCE through its voluminous orally preserved Vedic corpus and its continually edited and mythicized but still historically-bountiful Puranas [see Pargiter 1924, for the impressive & reliable data stored in them]. The amount of data is larger than that of any other contemporary civilization. The former has been called equivalent to a 'Tape recording' from the Bronze Age. India thus has a 5000 year *recorded history* (richer, larger, continuous and longer than any other ancient civilization!). However it is true, that Indians have only recently begun extracting reliable information from it. Spiritual reverence to most ancient texts and treating everything written in them as revelation instead of literature may be responsible for such a non-critical attitude. But that attitude also helped preserve these texts unlike Greek tradition which went extinct. Separating facts from myth and extracting coherent narratives from them (which is what the Greeks began to do) is actually easier than the unrivalled feat of transmitting such a huge mass of accretive data across 5000 years with minimal attritions and bottlenecks. True, Indians should have started critical-analysis much earlier, but it is a highly complex task involving highly complex texts. Max Mueller himself called the Biblical texts child's play compared to the difficulty of Indo-Iranian texts [Vedas and Avesta]. These Colonial historians, despite their frequent admiration for these texts, have done immense damage to *recorded* Bronze age Indian history by completely blackening it out from academic discussion in order to push their new pet-racist theory called AIT. A full 2000 years have vanished from Indian memory and discourse even though the Vedic & Puranic corpus preserves TONS of secular data about events in this period. And Indians are fixing it right now. This has profound consequences for humanity and will have effects on entire world history too, since bronze age India [~4000-3000 BCE] is the most likely and strongest candidate for the PIE Urheimat. The findings are going to be phenomenal. So we have preserved a second-to-none in quality & quantity of *our own history* with no help from anyone. The *help* from Whites/Colonial historians was to actually distort and erase entire millenniums from our recorded past. It has been the greatest intellectual violence anyone has done to us ever. We suffered and continue to suffer huge societal, political and psychological damage, bordering on risk of even civil war, from this evil distortion called AIT initiated by the likes of Mueller under EIC patronage and shoved down our throats for two centuries with Nehruvian and Marxist fans to flame it. Even though not a shred of valid proof supported it, then or now.
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a16z
a16z@a16z·
“What happens to the billion other websites if they aren’t getting traffic?” @cdixon raises a topic few are talking about: AI isn’t just disrupting search—it's changing the internet's economic model. For decades, websites provided platforms with content in exchange for traffic. AI flips this—content fuels its model, but traffic doesn’t always flow back. As users turn to AI for answers instead of the traditional search, control is becoming increasingly concentrated in the hands of a few dominant systems. He’s worried about the future of the internet, and what this shift means for creators. To address this, he asks: What new incentive structures or architectures should we be thinking about?
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Dr Sumit Sharma
Dr Sumit Sharma@dr_sumit_sharma·
You've been told cancer is a genetic disease. But what if everything you know about cancer is wrong? Dr. Thomas Seyfried's groundbreaking research shows cancer might actually be a metabolic disease. Here's why this changes everything:
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Accel in India
Accel in India@AccelIndia·
Rajesh, Chanakya, and Ramasubramanian are reimagining Indian logistics with @blackbuck. Their road to IPO is a story of perseverance, ambition, creativity, and relentless focus on solving real-world challenges for the trucking ecosystem which is a key part of the Indian economy. Today’s public listing is just another milestone in BlackBuck’s journey, as they march on with their timeless mission to meaningfully enhance the lives of truckers and shippers across India. It’s been a privilege for @Accel to be part of this journey since 2015. Anand Daniel, Partner at Accel, shares his reflections on BlackBuck’s journey in this blog: accel.com/?name=%2Fnotew… #AccelFamily #CelebratingBlackBuck
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Johnny Midnight ⚡️
Johnny Midnight ⚡️@its_The_Dr·
This is one of the most important videos on 𝕏. Take 6 minutes to hear Calley Means EXPOSE the past 100 YEARS of corruption in our Medical and Food industries. “John D. Rockefeller’s personal lawyer wrote the Flexner Report for Congress that set the standard … today for medical education. It literally says in the binding guidelines that holistic health and nutrition … is pseudoscience. It says we need to name the condition and cut it out or prescribe it. Rescinding the Flexner Report and having updated scientific education and standard of care guidelines based on what we’ve learned since 1909 about the majesty of the interconnectedness of our body is a really good start. John D. Rockefeller’s lawyer wrote this personal report. Why? Because John D. Rockefeller is the father of the pharmaceutical industry, and created pharmaceuticals from byproducts of oil production, and was the first investor in Johns Hopkins and other major medical schools. He created Johns Hopkins and the standard of residency training as a way to silo diseases, very intentionally, and then prescribe his products and interventions as the top pharmaceutical-maker. The medical schools were basically a distribution system to him. The medical industry saw the birth control pill in the late 1950s-1960s. The birth control pill was the first pill in world history that people took for longer than a couple weeks. The Sackler family … created Valium, and 30% of women in the United States in the 1970s were on Valium. We started creating all these psychiatric conditions, we started medicalizing heart disease, we started medicalizing type 2 diabetes, started creating academic research totally funded by the pharmaceutical industry. The second the Surgeon General report saying smoking wasn’t great came out, Philip Morris and R.J. Reynolds … used their cash piles, and by 1990, the three largest M&A deals were cigarette companies buying food companies. They did two things very, very intentionally: They took over the institutions of trust to say ultra-processed food was healthy, and then they took their scientists and rigged the food itself to make it more addictive.” @calleymeans @joerogan @CaseyMeansMD
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kris gopalakrishnan
kris gopalakrishnan@kris_sg·
Neuroscientists Just Discovered a Specific Type of Exercise Can Make You Stay Smarter, and for Much Longer. Advice you can follow. flip.it/oTrV9k
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David Chapman
David Chapman@Meaningness·
Wow, I did NOT know this: Buddhist logicians had discovered the Gettier problem c. 770 AD:
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