Shahed Toossi, MD

Starting with Dexmedetomidine for sedation after mod-severe TBI was associated with improved 6 month outcome and shorter LOS among those requiring ICP monitoring. #curingcoma journals.lww.com/ccmjournal/abs…

Neurological Examination Frequency and Time-to-Delirium... : Neurosurgery -> frequent exams come at a cost. Consider the risk/benefit. @CNS_Update @neurocritical journals.lww.com/neurosurgery/f…

In this comparison of tenecteplase vs alteplase for acute ischemic str... AIS in over 3,000 patients treated primarily via telemedicine in the kaiser Permanente system, both were equally safe with ICH rates lower than expected, and TNK had shorter door-to-needle times sciencedirect.com/science/articl…

@OrenFriedman @OrenFriedman haha! Axial slice through the thoracic gray matter in the spinal cord 🤓😂

Help @shahed2c - what part of the spinal cord is this ? I hated this part in medical school

Poor neuro-outcome in comatose survivors of CA -> clinical exam, biomarkers, EEG, neuroimaging reliable predictors within 1st week from ROSC; low/0% FPR but most low sensitivity & risk of bias/confounders: no certainty, multimodal approach prudent #FOAMres bit.ly/2FtF3vD

@OrenFriedman @ISeropianMD @PERTConsortium @vic_tapson @jameshorowitzmd @roblookstein @AntoniousAttall The CLOSURE study compared PFO closure with antiplatelets, antiplatelets alone, and AC alone.

@shahed2c @ISeropianMD @PERTConsortium @vic_tapson @jameshorowitzmd @roblookstein @AntoniousAttall So the PFO closure studies were closure versus just antiplatelet treatment right - not versus anticoagulation (like DOAC) ?

To all #PERT specialist. What’s your usually decisión re. treatment in a pt with #PE and #PFO?? Do you advise PFO closure? When? Always? Any data? @PERTConsortium @vic_tapson @jameshorowitzmd @roblookstein @AntoniousAttall thanks

@OrenFriedman @ISeropianMD @PERTConsortium @vic_tapson @jameshorowitzmd @roblookstein @AntoniousAttall Best data is in stroke ppx. Unclear benefit to close a PFO in patients destined for lifelong anticoagulation. Reasonable to consider closure if PFO Spencer grade >3, stroke is definitively from paradoxical embolus, and pt is young. Some experts weight in: aan.com/Guidelines/hom…

@ISeropianMD @PERTConsortium @vic_tapson @jameshorowitzmd @roblookstein @AntoniousAttall @shahed2c can shed some light on this - bringing this interesting issue/tweet back 2 life