Dr Shekeeb Mohammad

onlinelibrary.wiley.com/doi/10.1111/dm… With @RussellCDale and colleagues we describe the lived experience of children with 8 genetic disorders of chromatin dysregulation with autistic regression and abrupt-onset neuropsychiatric syndromes- could these be avoidable and reversible

CSIRO have now lost more jobs under the Albanese Governmet than under the Abbott Government. We have to do better on research funding and backing our scientists. smh.com.au/environment/cl…

We need to be talking about this research bureaucracy has become so out of control that it is harming patients

@aditya_gan3500 @AMahajanMD Disclaimer: I did not know the case or this publication at the time of recording 😊

@aditya_gan3500 @AMahajanMD Not sure about a link at the moment, but here is a reference to the case which is mentioned at the end of the podcast-(with credit to the original authors) journals.lww.com/annalsofian/fu…

MDS podcasts bring the focus back to clinical reasoning by this new avatar of Fahn and Marsden’s - WHAT IS IT? Thanks for including me in discussing this inagural case. Pls share with trainees in particular

Dear friends, I have something important to tell you. In December 2024, 'researchers' from multiple Indian Government Homeopathy institutions along with 'researchers' from Israeli Homeopathy institutes, published a randomized controlled trial that concluded that use of Homeopathic formulations in children during first 24 months of life reduced infections and antibiotics use compared to 'standard of care.' This was published in the prestigious European Journal of Pediatrics. The study was viral. It was all over the media and news here in South India and also in some National media and was Whatsapp 'proof' of Homeopathy being better than modern medicine in infants. The study was used to promote anti-vaccine sentiments and Homeopathy products in South India. Homeopaths hailed the study as 'path breaking' - also because the Ayush Ministry and Government Homeopathy practitioners were study authors involved in it. I read the study. I am trained in advanced statistics and research writing. The study was utter nonsense. And fraud. It looked like the authors did not even actually perform the study. I really doubted whether any patients were involved at all. I wrote a letter to the editor of the journal, asking him to kindly review the paper and investigate 'scientific integrity' and ethics. And after nearly 10 months of investigations by the Journal, Publisher and Research Integrity Team, we were proven correct. The paper was fraud and now it has been RETRACTED. @RetractionWatch The lesson here is that, if people really did understand what Homeopathy is and what its practitioners are, it is easy to find that it is clearly fraud. There is nothing in Homeopathy that works. It is unscientific utter nonsense. Every positive study on Homeopathy is mostly published in 'Homeopathy' journals. Sometimes, it infiltrates a real, valid journal (like in this case) and then it gets retracted because the scientific community is always alert. There are many such instances: See - pmc.ncbi.nlm.nih.gov/articles/PMC12… and nature.com/articles/s4159… and nature.com/articles/s4159… The worst part here is that all these Homeopathy practitioners who are authors of the study are working in Indian Govt. public health sector - meaning, their salary is paid from public funds and citizens taxes. These wastrels are eating away our hard earned money and using it to fund fraud. Who will stop these criminals? Even worse, the fraud, now retracted study was published as 'open access' in the European Journal of Pediatrics - which means, the authors paid £3090.00 GBP or $4990 USD, or €3990 EUR equivalent in INR to publish fraud. Where did they get this money from? Yes. Indian public tax money. Homeopathy needs to be booted out of this country. Parents, do not send your children to study Homeopathy even though India offers a 5 year course and gives them a "Dr." title at the end of it. They are not doctors. They are legitimized frauds and legalized quacks, as you can see from this retraction. "Homeopathy is a lively relic of the prescientific era. Not healthcare." @arifhussaintm Link: #author-information" target="_blank" rel="nofollow noopener">link.springer.com/article/10.100…

In a patient with dystonia and developmental delay, think of CTNNB1 if you get - Startle - Broad-based gait with lower limb hypertonia @shekeeb @MDCP_Journal #neurotwitter doi.org/10.1002/mdc3.7…

The NHMRC yesterday announced final allocations for the year. The 2025 success rate for Ideas grants was 10%, Investigator grants 13%, and Clinical Trials 9%. Australia's total spend on healthcare and technology innovation in medicine and biotech from the Medical Research Endowment Account and Medical Research Future Fund this year will equate to the cost of 0.004 submarines. We're spending more on a single submarine than we'll spend on medical research in 30 years. Medical research matters. A clever country invests in the things that matter.

Sarah Tabrizi first saw the data her team had been chasing for decades: evidence that gene-targeted therapy could slow the progression of Huntington's disease She is part of Nature’s 10, a list of people who shaped science in 2025 go.nature.com/4oKAWLF

@ec_bayram Many happy returns Ece- may the force always be with you !

My coordinator Ellie is da best 🤩 I work with awesome people 🥳

Sydenham Chorea Consensus Guidelines @SharmaSuvasini @shekeeb doi.org/10.1542/peds.2…

72% of Australians support a total ban on gambling ads. It’s been 881 days since the Murphy Report recommended that Parliament ban gambling advertising. 30% of Australian children aged 12 to 17 gamble - they lose nearly $20 million every year. Backbenchers agree, but the govt's refusing to act. We need a conscience vote on gambling ads. abc.net.au/news/2025-11-2…

A new nature published research on Medical-LLMs brings some bad news. ☹️ While GPT-5 shows progress in reducing hallucinations, it still fails in over half of difficult clinical scenarios. shows fluent doesn’t always mean being accurate or truly understanding. They show how progress in fluency and reasoning can mask persistent weaknesses — confident hallucinations, disappearing safety disclaimers, and even biosecurity concerns. In short, fluency doesn’t mean comprehension. To keep patients safe, we need stronger safeguards — independent testing, secure deployment, and clear accountability when AI enters the clinic. --- nature. com/articles/s41591-025-04008-8

Hard to understand a govt that blocks teenagers from social media but has *no* issue with them accessing online gambling platforms at all, or with them being bombarded with ads for online gambling. theage.com.au/technology/aus…

The @FNDSociety is launching a new virtual, on-demand CME course. Advanced Course for the Assessment & Management of Functional Neurological Disorder. Registration opens in late Oct & course goes live Monday Nov 3rd. @jonstoneneuro @AlanCarson15 @SarahLidstone @SelmaAybek

Join us for the 2025 Sir Syed Day evening and dinner in Sydney- Bowman Hall, Blacktown - knowledge sharing, networking, entertainment & an inspiring keynote speaker - Prof. Tanveer Zia, a leading voice in cyber security and digital forensics. trybooking.com/DEZEC

Tip of the day 💡: These can be normal appearances for a 4 month old- prominent anterior SUBARACHNOID spaces. These are not subdural collections.

DBSMatchMaker connects clinicians worldwide for deep brain stimulation in rare diseases. loom.ly/8LmNu8A

Nice article highlighting "identity erosion" in the era of sub-sub-specialization. @GreenJournal neurology.org/doi/10.1212/WN…

Thanks for all support so far ! Only $500 to go to be part of a bronze fundraiser to help people with multiple sclerosis receive the vital support, treatments, and services msgongride.org.au/fundraisers/sh…