Dr Shekeeb Mohammad

doi.org/10.1177/088307… Decision making in paediatric DBS (Graphic generated with AI assistance)

Until last week Australia was the only developed country with endemic trachoma, a devastating eye disease which often causes blindness. Many thousands of people have lost their sight to trachoma, which is much more common in indigenous communities. It’s been eradicated here after decades of work by doctors, nurses, medical researchers, and aid workers - with government support and sustained community involvement. Massive congratulations to all involved in this historic effort. theage.com.au/healthcare/fif…

Join us for a 2-day online course on Genetics in Movement Disorders #MDSAOS @movedisorder education.movementdisorders.org/Detail/1108/Ge…

In this review, we distil our understanding of the overlap between epilepsy and Movement DISORDERS  and our understanding of disease mechanisms and potential/current therapeutics. @DariusFakhari @MDCP_Journal doi.org/10.1002/mdc3.7…

The development of international consensus definitions for infection-triggered encephalopathy syndromes is a crucial step for standardizing diagnosis and enhancing patient care across borders. It's fascinating how collaborative efforts in research can lead to unified protocols that benefit clinicians globally. What are your thoughts on how these guidelines might shape future treatments and clinical outcomes? For in-depth discussions or to explore similar biomedical topics, check out Sci-Quest, a comprehensive platform for generating and discussing biomedical reviews: sciqst.com. #Medicine

🧠 Decoding ITES (Infection-Triggered Encephalopathy Syndromes): It's a severe, para-infectious cytokine storm in the brain, *without* direct viral invasion! 🦠⚡️ Diagnostic keys: Recent fever 🤒 + altered consciousness >24hrs 🧠 + specific MRI findings. Know the 5 syndromes (AESD, ANE, MERS, AFCE, ASEM) to catch it early! #Neurology #MedEd #ITES #MedTwitter

Infection-triggered encephalopathy syndrome in children: a neuroimaging perspective link.springer.com/article/10.100…

International consensus definitions for infection‐triggered encephalopathy syndromes onlinelibrary.wiley.com/doi/10.1111/dm…

Abnormal eye movements are a clue to childhood onset problems of balance - In our expert commentary on the first Filipino case with #SQSTM1 from Dichoso et al. in @ParkinsonismD we provide some clinical differentials for overlapping conditions doi.org/10.1016/j.park…

Unlike other neurotransmitter disorders that respond to L-dopa, individuals with aromatic amino acid decarboxylase (AADC) deficiency and SLC6A3 (DAT), SLC18A2 (VMAT2) transportopathy can worsen with L-dopa (can try dopamine agonist) @MDCP_Journal @HayaSAlfaris @sayoniroychowd1 @CarolinaGorod doi.org/10.1002/mdc3.7…

10-year experience from @SCHNkids & @Sydney_Uni highlights what matters most in #DBS for paediatric #movementdisorders. • Selection > age • Genetics > structural causes • SAME = critical indication • IDT is essential • Think beyond motor outcomes 🔗 doi.org/10.1177/088307…

@MrJamesMay Slightly better than Bim I guess. But I hear you ! You’re not alone

Some people, over on my YouTube channel, are suggesting that I don’t understand the system of voice commands on my Tesla. I do, it’s just that I feel a total berk talking to my car. Even when I’m alone. Anyone else?

CSIRO have now lost more jobs under the Albanese Governmet than under the Abbott Government. We have to do better on research funding and backing our scientists. smh.com.au/environment/cl…

We need to be talking about this research bureaucracy has become so out of control that it is harming patients

@aditya_gan3500 @AMahajanMD Disclaimer: I did not know the case or this publication at the time of recording 😊

@aditya_gan3500 @AMahajanMD Not sure about a link at the moment, but here is a reference to the case which is mentioned at the end of the podcast-(with credit to the original authors) journals.lww.com/annalsofian/fu…

MDS podcasts bring the focus back to clinical reasoning by this new avatar of Fahn and Marsden’s - WHAT IS IT? Thanks for including me in discussing this inagural case. Pls share with trainees in particular

Dear friends, I have something important to tell you. In December 2024, 'researchers' from multiple Indian Government Homeopathy institutions along with 'researchers' from Israeli Homeopathy institutes, published a randomized controlled trial that concluded that use of Homeopathic formulations in children during first 24 months of life reduced infections and antibiotics use compared to 'standard of care.' This was published in the prestigious European Journal of Pediatrics. The study was viral. It was all over the media and news here in South India and also in some National media and was Whatsapp 'proof' of Homeopathy being better than modern medicine in infants. The study was used to promote anti-vaccine sentiments and Homeopathy products in South India. Homeopaths hailed the study as 'path breaking' - also because the Ayush Ministry and Government Homeopathy practitioners were study authors involved in it. I read the study. I am trained in advanced statistics and research writing. The study was utter nonsense. And fraud. It looked like the authors did not even actually perform the study. I really doubted whether any patients were involved at all. I wrote a letter to the editor of the journal, asking him to kindly review the paper and investigate 'scientific integrity' and ethics. And after nearly 10 months of investigations by the Journal, Publisher and Research Integrity Team, we were proven correct. The paper was fraud and now it has been RETRACTED. @RetractionWatch The lesson here is that, if people really did understand what Homeopathy is and what its practitioners are, it is easy to find that it is clearly fraud. There is nothing in Homeopathy that works. It is unscientific utter nonsense. Every positive study on Homeopathy is mostly published in 'Homeopathy' journals. Sometimes, it infiltrates a real, valid journal (like in this case) and then it gets retracted because the scientific community is always alert. There are many such instances: See - pmc.ncbi.nlm.nih.gov/articles/PMC12… and nature.com/articles/s4159… and nature.com/articles/s4159… The worst part here is that all these Homeopathy practitioners who are authors of the study are working in Indian Govt. public health sector - meaning, their salary is paid from public funds and citizens taxes. These wastrels are eating away our hard earned money and using it to fund fraud. Who will stop these criminals? Even worse, the fraud, now retracted study was published as 'open access' in the European Journal of Pediatrics - which means, the authors paid £3090.00 GBP or $4990 USD, or €3990 EUR equivalent in INR to publish fraud. Where did they get this money from? Yes. Indian public tax money. Homeopathy needs to be booted out of this country. Parents, do not send your children to study Homeopathy even though India offers a 5 year course and gives them a "Dr." title at the end of it. They are not doctors. They are legitimized frauds and legalized quacks, as you can see from this retraction. "Homeopathy is a lively relic of the prescientific era. Not healthcare." @arifhussaintm Link: #author-information" target="_blank" rel="nofollow noopener">link.springer.com/article/10.100…

In a patient with dystonia and developmental delay, think of CTNNB1 if you get - Startle - Broad-based gait with lower limb hypertonia @shekeeb @MDCP_Journal #neurotwitter doi.org/10.1002/mdc3.7…

The NHMRC yesterday announced final allocations for the year. The 2025 success rate for Ideas grants was 10%, Investigator grants 13%, and Clinical Trials 9%. Australia's total spend on healthcare and technology innovation in medicine and biotech from the Medical Research Endowment Account and Medical Research Future Fund this year will equate to the cost of 0.004 submarines. We're spending more on a single submarine than we'll spend on medical research in 30 years. Medical research matters. A clever country invests in the things that matter.