
Cryo-EM structures of human SLFN11 bound to tRNA or ssDNA uncover the tRNA endoribonuclease mechanism and how it may block stressed replication forks. Check out our new paper at: nature.com/articles/s4146…
Simon Wenzl
11 posts

@simonjwenzl
PhD Candidate @TU_Muenchen | biochemistry, cryo-EM, and uncharacterized enzymes

Cryo-EM structures of human SLFN11 bound to tRNA or ssDNA uncover the tRNA endoribonuclease mechanism and how it may block stressed replication forks. Check out our new paper at: nature.com/articles/s4146…








New paper out! We obtained conformational snapshots by using ATP analogues to reveal Mot1's special remodeling mechanism: gripping, bending and rotating upstream DNA to dislodge TBP from the TATA-box. @StephanWoike et al. nature.com/articles/s4159…



Congratulations to the recipients of the 2022 FEBS Excellence Awards! These awards provide €100,000 funding to early-career group leaders working in a FEBS country: more info at febs.org/news/febs-exce… #GroupLeader #biochemistry #molecularbiology #cellbiology #biophysics
