Thaís Dal'Sasso

Reconstruction of ancestral protein sequences using autoregressive generative models biorxiv.org/cgi/content/sh… #biorxiv_bioinfo

Novel structural insights at the extracellular plant-pathogen interface sciencedirect.com/science/articl…

A new preprint from @kseniakrasileva lab: resurrecting an NLR to recognize its effector escape mutant!

A year's pay for a Brazilian post doc on a federal fellowship.

N-terminal domains of NLR immune receptors exhibit structural and functional similarities across divergent plant lineages @ThePlantCell by @Khongsam_Chia et al. @Phil_Carella lab with an NLR N-terminal domain structure network analysis by @AlbinTeulet academic.oup.com/plcell/article…

REVIEW: Pathogen Perception and Signalling in Plant Immunity (Peter N Dodds, Jian Chen, Megan A Outram) buff.ly/3Uk3H6F @ASPB #PlantSci

RNA language models predict mutations that improve RNA function A great work from Jennifer Dounda and Jamie Cate's Lab! - Use Genome Taxonomy Database (GTDB) to build the GARNET (Gtdb Acquired RNa with Environmental Temperatures) database - Train a generative GNN model using a 23S rRNA MSA with structural conditioning - Train a nano-GPT based RNA language Model that can predict optimal mutation for increased thermostability

How do "ghost" lineages impact use of branch length methods to infer timing of #HGT events? @toni_gabaldon &co discuss key considerations regarding the potential effect of such missing lineages: plos.io/4crpJLl Response by @damdevienne &co: plos.io/49YqVEl

Excited to share the final version of our work on the evolutionary history of the genus Dimorphandra! Our study sheds light on its origins and habitat shifts, offering insights into the evolution of Neotropical flora. link.springer.com/article/10.100…

Our paper is out in Nature com! Well done, Bruno! I'm so proud of this work! Evolutionary trajectory of pattern recognition receptors in plants nature.com/articles/s4146…

Congratulations to @marielapga for the interesting study about the ecology/epidemiology of bleeding stem canker of Nothofagus spp. in Chile caused by #Phytophthora pseudosyringae. doi.org/10.1111/ppa.13…. Thanks @BS_PP for the great experience during the publishing process!

Exploring potential surrogate systems for studying the early steps of the Sporisorium scitamineum pathogenesis | Phytopathology® apsjournals.apsnet.org/doi/10.1094/PH…

@CrestanaGustavo @GilDoVigor A amizade de milhões que o Brasil precisava

@GilDoVigor Gil, é sempre um prazer conversar contigo! O teu brilhantismo vai render muitos frutos ao nosso país, sem dúvidas! Grandes momentos virão! Você é o cara!

Amigo gatinho no Thanksgiving!!!

Our work predicting multiple conformations by combining sequence clustering and AlphaFold2 is in press at @Nature! Thrilled to get to share - now includes experimental validation for several tests of AF-Cluster, led by the incredible @ademi_moyin! go.nature.com/49uCNxU

I'm honored to be part of this great work, and congratulations to @viniciuRocha_MT on another paper for his PhD. Have a look at: sciencedirect.com/science/articl…

How to use AI in plant-pathogen interaction, please see our recent work. nature.com/articles/s4146…

"SSDraw: software for generating comparative protein secondary structure diagrams" This looks straightforward to use biorxiv.org/content/10.110… github.com/ethanchen1301/…

pyCirclize: a Python implementation of circlize github.com/moshi4/pyCircl…

Reviewing the key discovery of effector biology/identification, Amelia H. Lovelace et al. discuss features, bioinformatic analysis tools, and breakthroughs related to effectors in various bacterial, fungal, and oomycete pathogens of plants. Read for free: doi.org/10.1094/PHYTO-…

Network analysis lets you study complex patterns and relationships and their connections to each other. Check out the Primer for mor details: go.nature.com/38xzIlv