Tessa Lochetto
314 posts
Tessa Lochetto
@tloch_
Molecular Cell Biology PhD Candidate & AHA Predoc Fellow | Lab of Dr. Natalie Niemi @nieminm @WUSM_BMB | Striated muscle physiology & mitochondrial maintenance
St Louis, MO Katılım Mayıs 2022
429 Takip Edilen294 Takipçiler
The first paper from the Crewe lab is online today. We found that macrophage-meditated clearance of EVs is a major determinate of circulating adipocyte EV levels. This clearance is disrupted in obesity. A huge effort by Snigdha Tiash!
cell.com/cell-metabolis…
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Tessa Lochetto retweetledi
Thrilled to share our work "Recessive PPTC7 deficiency triggers excessive mitophagy to cause a severe inborn error of metabolism with hypomyelinating leukodystrophy" - a collaborative effort documenting the first cases of PPTC7 mutations in humans. 1/n
researchsquare.com/article/rs-881…
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Tessa Lochetto retweetledi
A big day for the lab! Huge congratulations to the newly minted Dr. Jerry Wei for successfully defending his thesis! 🎓🥳🎉
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Tessa Lochetto retweetledi
Really thrilled to share our work on mitochondrial presequence strength @JCellBiol. We establish quantitative parameters to better define "strong" and "weak" presequences in vitro and in vivo. This work was spearheaded by the ever talented Youmian Yan, a grad student in my lab.
Journal of Cell Biology@JCellBiol
Youmian Yan, @IanofBristol, @nieminm et al. define quantitative parameters underlying the strength of mitochondrial-targeting presequences, and demonstrate that yeast require strong presequences to facilitate select metabolic pathways in #mitochondria. hubs.la/Q03-1x5l0
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Tessa Lochetto retweetledi
Very excited to share our latest work, “Mitochondrial presequences harbor variable strengths to maintain organellar function,” led by the fantastically talented @WashUBBSB graduate student Youmian Yan. A 🧵
biorxiv.org/content/10.110…
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My heart hurts for my Alma mater right now. My prayers go out to the families and loved ones affected by this tragedy. abcnews.go.com/amp/US/active-…
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In search of a modified gomori stain kit that will stain mouse sk. muscle cryosections (myofibers = blue/green, nuclei = red/purple, ragged red fibers = red). Has anyone used VitroView?? #myotwitter
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A wonderful conference! I am so glad I got to attend this meeting during my PhD career. I look forward to attending more in the future years!
UF Myology Institute@UFMyology
A MILLION thank yous to everyone who joined us for the 2025 ASMB Conference. We had a great time talking science, catching up, social activities, and of course all those amazing presentations!! We can't do it without the sponsors so one last shout out... Thank you!!!
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@RazaniLab @jclinicalinvest @yushengyeh So happy to see this out! Congratulations @yushengyeh, @RazaniLab & more!
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Wondered how #adipocyte #fat release #lipid via #lipolysis in #fasting, cold exposure? Multi-year @Razanilab effort in @jclinicalinvest by postdoc maven @yushengyeh identifies #lysosome lipolysis (LAL) as major way on par with known cytosolic route (ATGL)
jci.org/articles/view/…
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Română
Thrilled to be part of this exciting project on Leishmania and Crithidia doublet microtubule structures. Thanks to my two amazing PIs @RuiZhangWUSTL @PolinaLishko and our fabulous collaborators @alanbrownhms lab, @Gluenzlab lab, and @Zephyris lab🎉🎉🎉
Rui Zhang@RuiZhangWUSTL
Another wonderful collaboration with @alanbrownhms lab. The Zhang lab together with @PolinaLishko lab (co-first author @QingweiN) contribute the doublet microtubule structure from Crithidia fasciculata, a model organism that infects mosquitoes. science.org/doi/10.1126/sc…
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Excited to share that our recent story on how massive membrane assemblies of HflK/C regulate protein degradation by FtsH AAA proteases is now online in @EMBOJournal. Check it out and enjoy!
embopress.org/doi/full/10.10…
#StructuralBiology #Proteases #MembraneProteins
Alireza Ghanbarpour@AGhanbarpour
Thrilled to share our preprint on the structure of a nautilus-like assembly of membrane proteins, HflK/C, that regulate the FtsH AAA protease activity, a key component of bacterial inner membrane protein degradation machinery. (1/n) bit.ly/4dotfpJ
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@tombrettlab You’re an awesome mentor. I’m sure this meant so much to her!
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Congrats Tessa!
Tessa Lochetto@tloch_
So incredibly happy to announce I have been awarded a 2-year Predoctoral Fellowship from the @AHAScience. Thank you to my amazing PI (@nieminm), co-mentor (@bnfinck), rec letter writers, and @The_DataDragon for all the support, feedback, and encouragement during this process.🫀🥳
Català
So incredibly happy to announce I have been awarded a 2-year Predoctoral Fellowship from the @AHAScience. Thank you to my amazing PI (@nieminm), co-mentor (@bnfinck), rec letter writers, and @The_DataDragon for all the support, feedback, and encouragement during this process.🫀🥳
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Woooooo!!! 🎉🎉🎉🎉🎉🎉
Tessa Lochetto@tloch_
So incredibly happy to announce I have been awarded a 2-year Predoctoral Fellowship from the @AHAScience. Thank you to my amazing PI (@nieminm), co-mentor (@bnfinck), rec letter writers, and @The_DataDragon for all the support, feedback, and encouragement during this process.🫀🥳
Congratulations @tloch_ !!!!!!
Tessa Lochetto@tloch_
So incredibly happy to announce I have been awarded a 2-year Predoctoral Fellowship from the @AHAScience. Thank you to my amazing PI (@nieminm), co-mentor (@bnfinck), rec letter writers, and @The_DataDragon for all the support, feedback, and encouragement during this process.🫀🥳
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Big s/o to my rec letter writers - @lab_meyer, @alexholehouse, & Dr. Robb Tomko (FSU) as I could not do this without them. Also, thank you to my lab mates for the supportive culture they foster and their continued belief in me.
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Tessa Lochetto retweetledi
Interested in BNIP3/NIX-mediated mitophagy? Check out our new review, written with @LabFriedman, about recent advances in the field and our thoughts on the regulation of these mitophagy receptors in space and time. doi.org/10.1042/BST202…
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