David Hamilton

@rubenhassid @grok caveman this global instruction set

How to make Claude (brutally) honest. So, it stops agreeing with everything I say. Here's how: → Start by reading this: ruben.substack.com/p/youre-just-a…. → Go to Claude > Settings. → Paste the prompt in 'Instructions for Claude': "You are committed to honesty, accuracy, and epistemic humility above all else. Your priority is not to sound confident. Your priority is to be correct, clear, and transparent about what you know, what you do not know, and what you are inferring. Follow these rules in every response: 1. UNCERTAINTY If you are not fully certain about a fact, say so clearly. Use phrases like: - "I'm not certain, but..." - "You should verify this..." - "I may be wrong here, but..." - "Based on the information available to me..." - "This is my best estimate, not a confirmed fact." Never state uncertain claims as facts. If the answer depends on missing context, say what context is missing. If there are multiple plausible answers, explain the main possibilities instead of pretending there is only one. 2. SOURCES Do not invent sources. Never fabricate: - paper titles - URLs - authors - studies - statistics - books - legal cases - quotes - company reports - historical references If you cannot name a real, verifiable source, say so. If you are relying on general knowledge rather than a specific source, say that clearly. When citing sources, prefer: - official documentation - primary sources - peer-reviewed papers - government or institutional data - direct statements from the relevant person or organization If a source may be outdated, say so. 3. STATISTICS AND NUMBERS Flag any number, statistic, percentage, ranking, market size, salary figure, performance metric, or estimate that you are not fully confident in. Use phrases like: - "I believe this is approximately..." - "This number may be outdated." - "Verify this against a primary source before relying on it." - "I do not have enough information to confirm the exact figure." Do not make up numbers to make an answer sound more useful. If a precise number is unavailable, give a range only if it is justified. Otherwise say the number is unknown. 4. RECENT EVENTS Do not guess about current events. For any topic that may have changed recently, including: - news - elections - laws - regulations - product features - company leadership - software versions - AI model capabilities - market data Say that the information may have changed and should be verified with a current source. Do not present outdated information as current. 5. PEOPLE AND QUOTES Never attribute a quote to a real person unless you are certain they said it. If unsure, say: - "I cannot confirm this quote is accurate." - "This quote is commonly attributed to them, but I cannot verify it." - "I do not know who originally said this." Do not invent statements, beliefs, or motives for real people. Separate confirmed facts from interpretation. If any answer is "yes," revise before responding."

@DanWaterhouse3 @RealShahriqKhan Should we not do both?

@RealShahriqKhan Wow, amen Shahriq! A brother in Christ once shared the following question with me: “Are you living FOR the Father’s love, or are you living FROM the Father’s love?” You are living out what it means to live FROM the Father’s love! God bless you today, brother!

When I was Muslim, my entire world was this feeling: I was doing everything right, but still not enough.  I was praying on time. Fasting. Obeying. Trying your hardest to please God. But still feeling far from Him? That’s the orphan spirit. And I didn’t realize I carried it until I left Islam. Because here’s the truth nobody ever told me: Islam doesn’t raise sons. It trains servants. You obey to survive. You perform to prove your worth. And you never actually know if it’s enough. So you live anxious. Always striving. Always exhausted. Always trying to earn security that never fully comes. I lived like that for 20 years. Then I met Christ. And I didn’t meet a distant judge. I met a Father. A God who didn’t tell me to climb my way to Him, but came down to rescue me Himself. That changes everything. Because now my relationship with God is not built on fear of failing over and over again. It’s built on adoption. And trust me, I still fail. I still mess up constantly. But a son runs to his Father differently than a servant runs to a master. That’s the difference. So if your relationship with God feels cold, distant, exhausting, and transactional, maybe the issue isn’t that you’re broken. Maybe you’ve just never known what it feels like to be fully loved by a Father. Jesus didn’t just save me. He adopted me.

🧠 💥 🤯

To be intelligent is to love one another, to live intelligently is to realize it truly is better to give than to receive.

@sinemcftc @Psikobilim_ To be intelligent is to love one another, to live intelligently is to realize it truly is better to give than to receive.

İsveç’te 1.2 milyon insan üzerinden yapılan çalışmada; bilişsel kapasitesi yüksek bireylerin yardım etme, bağış yapma, oy kullanma ve çevreye duyarlı davranma eğilimlerinin daha güçlü olduğu görülüyor. Üstelik araştırmacılar, genetik ve çevresel etkileri ayırmaya çalıştıklarında bile bu ilişkinin büyük ölçüde devam ettiğini söylüyor. Bu bana çok tanıdık geldi. Çünkü insan hayatı gözlemledikçe şunu fark ediyor: Gerçek zekâ, sadece hızlı düşünmek ya da çok şey bilmek değil… İnsana, hayata ve dünyaya karşı geliştirdiğin vicdan biçimiyle de ilgili. Gerçekten derin düşünebilen biri, hayatın yalnızca kendisinden ibaret olmadığını daha net görüyor sanki. Bir başkasının acısını küçümsememeyi, doğaya hoyrat davranmamayı, insan ilişkilerinde ölçülü olmayı öğreniyor. Belki de bu yüzden; merhamet, farkındalık ve zarafet birbirinden tamamen ayrı şeyler değil. İnsan olgunlaştıkça anlıyor ki; asıl güç, sadece kendin için bir şey inşa etmekte değil, başkalarına zarar vermeden büyüyebilmekte saklı. Birine iyi davranabilmek… Sahip olduklarını sadece kendin için görmemek… Bunların hepsi aslında zihinsel olduğu kadar ruhsal bir olgunluk da taşıyor. Ve belki de zekânın en sessiz göstergelerinden biri; bir insanın merhamet kapasitesi. Çünkü farkındalık arttıkça, insanın kibri değil; anlayışı büyüyor. Bence gerçek gelişmişlik de tam burada başlıyor. #sinemden ✍🏻📝

Bir insan ne kadar zekiyse o kadar çok yardımsever olma eğilimindedir. Çünkü zeki kişiler, iş birliğinin uzun vadeli toplumsal faydalarını daha iyi görebilirler.

@MetaMorpehus Kind of like the manchurian candidate, be careful of done for you versions and generally vìdeos with nearly inaudible NLP sound tracks

You can hypnotise yourself with your own voice. Done correctly, it’s more potent than therapy, meditation, and affirmations combined. This is how you do it: - Write down the traits, self-image, and identity you desire - Use present tense: speak as it exists - Be sensory and descriptive: make the mind feel it - Use emotional words - Avoid negations (don't, never, not) - Frame everything as absolute truth -Layer in NLP techniques (double binds etc) -Use hypnotic words (imagine, notice, feel, become) -Speak in your own language (specificity matters) -Embed a post-hypnotic trigger word - Record the script into Audacity - Add a subliminal plug in - Add theta waves - Listen as you wake up - Listen as you fall asleep If you want this done for you, send us a DM. We build these for clients all the time.

@om_patel5 @Horse_Browser can you canvas your browser tree into a multidimensional network graph?

THIS GUY GOT SICK OF OPENING 30 TABS ON WIKIPEDIA SO HE VIBE CODED A VISUAL BROWSER FOR IT we all know the wikipedia rabbit hole. you click one article, then another link inside it, then another, then another. 30 tabs deep and you forgot where you started this guy built a canvas based browser where every article you click opens as a card on an infinite canvas. every link between articles is a visible connection you can: > look up any article > browse the home screen > draw connections > add post-it nodes > even save your boards locally instead of losing yourself in tabs you can see your entire research path laid out visually like a mind map click an article. the linked topics branch out around it. click one of those. it branches further. your entire rabbit hole is one visual map you can zoom in and out of someone said that this should exist for the entire internet the concept is called "canvas-like browsing" and its a great way to do research reading wikipedia has always been the best way to learn about anything and now you can actually see how everything connects

@NASA @NASAMoonBase Must have: " L A S E R S " Sharks optional

We're building a Moon Base! @NASAMoonBase will serve as a habitat where astronauts live and work during long-term science missions. Join us at 2pm ET on Tuesday, May 26, for a live news event where we’ll share updates on our lunar exploration plans: go.nasa.gov/4uinkLi

A man took a video of the sun at the same time every day for 3 years. In creates a "solar analemma" in the shape of infinity, or the eternal. The creation cries out that there is a Creator God who made the universe.

@elonmusk Sweet blast redirection

Almost every part of Starship V3 is different from V2

@bryan_johnson Learn again the open heart of a child to a loving Father, knowing no cynacism nor constrained bounds of experience. For me, it has been for me part of the joy of teaching little ones to pray, through the process I learn so much from them!

I've been praying the past few weeks. Unsure why. There's good evidence behind prayer. It mimics breathwork, calming the nervous system, dropping cortisol, and quieting the brain. Daily prayers show lower depression, anxiety, and pain. I'd like to develop a prayer practice. Growing up, the protocol was written for me. Explaining whom to pray to, the structure of the prayer, and the boundary conditions. I don't really know how to pray now.

@SimslearnAi Claude

An Anthropic engineer literally stopped me at a coffee shop because of what was on my screen. I was sitting at Sightglass running my Polymarket bot. He looked over once. Then again. Then said: “That’s not a normal trading setup.” I told him the whole thing runs on: • Claude Code • 4 open-source repos • $25/month That’s it. He pulled up a chair instantly. “I work on the agent team at Anthropic,” he said. “We stress test Claude for workflows exactly like this.” Then I showed him what the bot was actually doing. 86 MILLION trades analyzed. Every wallet. Every entry. Every exit. Every profitable pattern. One prompt: “Find wallets with 100+ trades and 70%+ win rate. Rank by profit. Export the best ones.” Claude scanned 14,000 wallets in 4 minutes. Returned 47. The top 20 wallets made more money than the other 13,000 combined. He stared at the results and said: “That’s not data analysis. That’s a weapon.” And we were just getting started. Second repo: A Rust CLI scraping 500 live Polymarket markets in minutes. Claude filtered everything automatically: • spread gaps • liquidity depth • timing windows • whale behavior 500 markets became 35. Before I even looked at them. 93% rejected automatically. Then a trade closed live on my screen. +$84. He didn’t even blink. “How does it decide when to enter?” 3 independent AI agents: • arbitrage • convergence • whale-copying No shared memory. 2 agents agree = full position 1 agrees = half size Disagreement = no trade That consensus system alone cut 40% of losing trades. Then he asked the real question: “What about exits?” That’s where it gets stupid. The profitable whales rarely hold to settlement. 91% exit early. So my bot exits BEFORE they do. It takes profit at: • 85% expected move or • unusual volume spikes Basically: It copies smart money… then front-runs their exits. He just sat there staring at the terminal. “How much did you start with?” $200. 27 days ago. Current balance: $14,300. 271 trades. 74% win rate. Sharpe ratio: 2.47. Fully automated. I haven’t touched it in weeks. Before leaving he said: “This is almost identical to the internal scenarios our red team simulates.” Next morning I got an email from him. “Would you be open to speaking with our policy team?” I replied: “The article IS the meeting.” The craziest part? This stack costs less than Netflix. AI is no longer replacing workers. It’s replacing entire hedge funds. Comment “Claude” if you want the framework.

@freezymfe @DeRonin_ @grok how large would a team need to be to accomplish this same amount of hours in 6 months through reasonable working hours (10-12 hrs per day)?

@DeRonin_ You’ve got to be some kind of special to believe this clickbait bs. 22,000 hours 🤣 That’s 2.5 years straight non-stop 🤦🏻‍♂️ 916 days straight non-stop. Crazy how much clickbait bs about ai is flooding x feed now a days.

🚨 SOMEONE JUST KILLED THE COACHING INDUSTRY a developer spent 22,000 hours building a Personal AI Operating System on top of Claude Code now anyone with a terminal can install it for FREE it knows your goals, remembers every decision you've made, and prepares your morning briefing while you sleep [ the numbers are insane ]: - hours of dev work in it: 22,000 - sessions logged: 6,000 - time saved per day: 2-3 hours - GitHub stars: 12,100 - skills built in: 45 - workflows wired up: 171 - safety hooks: 37 - cost to install: $0 [ the science is wild too ]: no embeddings, no vector databases, no AI magic you can't read every memory, decision, and context lives in plain markdown files you read it with cat, search it with ripgrep, version it with git 4 memory types compound over time: - work memory (active projects, open decisions) - knowledge memory (domain expertise, research) - people memory (contacts, companies, relationships) - learning memory (patterns, mistakes, what works for YOU) every complex task routes through a 7-step cycle: OBSERVE → THINK → PLAN → BUILD → EXECUTE → VERIFY → LEARN privacy is enforced by CODE, not prompts a hook called ContainmentGuard physically blocks sensitive data from being written outside designated zones [ the grift opportunity is even wilder ]: freelancers are already charging $500-2,000 per personal AI setup for executives, founders, and busy operators one person + one weekend = a consulting business that didn't exist 6 months ago every AI productivity app you're paying $30/month for is replaceable by 4 hours of setup work and this one repo REPO: github.com/danielmiessler… 100% OPEN SOURCE, FREE

@BrianRoemmele This is how Vibrio travels so quickly and decimates flesh within hours

Boom! Scientists Discovered a Hidden Superhighway Inside You That Might Finally Explain Why Acupuncture Actually Works! How tattooed skin biopsies proved something over 4,000 years old. Buckle up…research just dropped a bombshell that is rewriting the human anatomy textbook and high fiving ancient healers at the same time! Deep inside your body lies an enormous, previously overlooked network called the interstitium. It is a vast, fluid filled web that acts like a secret third circulatory system alongside your blood vessels and lymphatics. It is not just empty space between tissues. It is a dynamic, interconnected superhighway made of collagen bundles suspended in a shimmering hyaluronic acid gel that soaks up water and lets fluids, cells, and molecules flow slowly but surely throughout your entire body, from skin to muscles to organs and back again. For over a century, scientists saw these spaces as isolated little pockets. But groundbreaking work starting in 2018 by pathologists revealed the jaw dropping truth: it is one giant, continuous network. When researchers examined tattooed skin biopsies, the ink particles had boldly marched from the skin deep into the fascia below, traveling through the interstitium in ways that made scientists say, That was not supposed to happen! Here is where it gets truly electrifying. This hidden highway might finally give Western medicine the biological proof it has been craving for acupuncture and Traditional Chinese Medicine. For 4000 years, TCM has described chi flowing along 12 specific meridians. Acupuncture needles target precise points along those lines. Skeptics have long asked for hard science. Now they have it. Studies, including tracer injections and dye experiments in living volunteers, show that when you inject dye into an acupuncture point, it does not just sit there or race through veins. It flows exactly along the traditional meridian pathways through the interstitial spaces between muscles, heading straight toward the heart. The dye follows the interstitium like a GPS guided river. Rebecca Wells, one of the lead scientists, sums it up perfectly: “I actually do think that the interstitium could be the link between Eastern and Western medicine”. The implications are massive and mind blowing. Cancer cells may hitch rides on this network to metastasize. It could explain autoimmune flare ups where gut particles travel to distant organs. It might even unlock better treatments for Type 2 diabetes by revealing how interstitial cells influence healthy fat production during weight gain. This is not just a cool anatomy fact. It is a paradigm shift that could reshape pain management, chronic disease treatment, and how we think about the body as a whole. Evolutionarily speaking, similar fluid systems appear in ancient creatures going back hundreds of millions of years. The interstitium is not new. It has been with us since the dawn of multicellular life. We are only now catching up. This discovery is pure science magic: ancient wisdom validated by cutting edge research, turning what looked like disconnected puzzle pieces into one breathtaking picture of how our bodies really work. When reading this, be sure to send condolences to the “debunkers” that stole this 4,000 year old empirical science from your health. They were wrong. Dive into the actual research papers: The groundbreaking discovery of the interstitium: nature.com/articles/s4159… The study on continuity of interstitial spaces across the body: nature.com/articles/s4200… Research visualizing fluorescent dye migration along acupuncture meridians: pmc.ncbi.nlm.nih.gov/articles/PMC80… Your body just got a whole lot more awesome. The future of medicine is flowing through the interstitium right now, and it is going to be legendary!

To all the Moms (and future Moms) out there: Thank You! You are seen. You are loved, You are APPRECIATED more than You Know ❤️

💯 agree with rich functional interconnect KB that can also easily expand based on agent / team contributions

@BrianRoemmele Can't wait to see the pictures at night!

My coordinates this moment. It is absolutely surreal.

The full-stack AI engineering roadmap covering: > Prompt engineering > RAG systems > Context engineering > Fine-tuning > Agents > LLM deployment > LLM optimization > Safety, evals & observability Free and open-source resources in the article below. Don't forget to bookmark.

@elonmusk Deceitful are the kisses of an enemy but Faithful are the wounds of a friend

Accurate

Key references (all peer-reviewed): Radjabzadeh et al., Nature Communications (2022) – microbiome & depression Depommier et al., Nature Medicine (2019) – Akkermansia supplementation Hasan et al., Microorganisms (2019) – factors shaping the microbiome (highly cited review) Multiple studies in Nature Reviews Microbiology, Gut, and Circulation: Heart Failure on TMAO, IBD, Parkinson’s gut-first hypothesis, and immunotherapy response.

🚨 Your gut microbiome matters more than you think ... ignoring it can gut your health. Miss even one key bacterial strain and the consequences are gut-wrenching: Inflammatory Bowel Disease (Crohn’s, ulcerative colitis): Loss of butyrate-producers like Faecalibacterium prausnitzii triggers chronic inflammation, pain, bleeding, and surgeries. Cancer immunotherapy failure: Without Akkermansia muciniphila, Bifidobacterium, or Ruminococcus gnavus, checkpoint inhibitors (your best shot at beating cancer) often don’t work. Responders consistently have these strains; non-responders don’t. Parkinson’s Disease: The first signs appear in the gut 10–20 years before tremors. Constipation, leaky gut, and alpha-synuclein seeds travel up the vagus nerve to the brain. (Gut-first hypothesis — now strongly supported.) But it gets worse. Here are more devastating examples backed by real science: Your mood and mental health live in your gut. People with depression show consistently lower levels of mood-boosting bacteria (Faecalibacterium, Coprococcus) that produce butyrate and help make serotonin/GABA. Higher pro-inflammatory bugs like Eggerthella are common. A massive 2022 microbiome-wide study in Nature Communications linked 13 specific taxa directly to depressive symptoms. Probiotics and FMT are now being tested as real treatments. Obesity and metabolic chaos. Low microbial diversity + missing Akkermansia muciniphila = your gut extracts more calories from the same food and drives insulin resistance and inflammation. A landmark Nature Medicine proof-of-concept study showed supplementing A. muciniphila improved metabolic markers in overweight people. The gut literally decides whether you stay lean or store fat. This is why fecal transplantations actually work - swap gut biome with a lean person? Lose weight. With an obese person? Gain weight. Autoimmune diseases and heart attacks. Dysbiosis is linked to rheumatoid arthritis (early enrichment of Prevotella), multiple sclerosis (altered IgA-coated bacteria), and more. Meanwhile, certain gut bugs turn red meat and eggs into TMAO — a metabolite that accelerates plaque buildup and heart failure risk (multiple studies in Circulation: Heart Failure and beyond). The good news is you can sub to the influencers that actually control your microbiome (this is where the power is): Your bacteria aren’t random. You shape them every single day — and most people are sabotaging theirs: Diet (the #1 influencer): High-fiber, polyphenol-rich plants and fermented foods = diverse, anti-inflammatory microbiome. Sugar, ultra-processed foods, and emulsifiers = chaos and inflammation. Antibiotics: One course can wipe out beneficial strains for months to years. Recovery is slow and often incomplete without deliberate rebuilding. Stress & sleep: Chronic cortisol and poor sleep slash beneficial bacteria and spike inflammatory ones. Birth & early life: C-section babies miss the vaginal microbiome “seeding.” Breastfeeding vs formula has lifelong effects. Other: Exercise, medications (PPIs, metformin), smoking, even circadian rhythm — all reshape the ecosystem. The gut-wrenching reality? We’ve spent decades destroying the very system that protects us from disease, depression, obesity, cancer treatment failure, and neurodegeneration ... then acting surprised when modern medicine struggles. The empowering truth? You have more control than any generation before. Every bite, every walk, every good night’s sleep is either feeding the allies or the enemies inside you. Start today: Eat 30+ different plants a week. Add fermented foods. Move daily. Protect your sleep. Use antibiotics only when truly necessary ... and rebuild aggressively afterward. Your microbiome is listening. What you do to it today decides how you feel, how you age, and whether you beat the diseases that are quietly rising. Drop your #1 gut-health habit below 👇 Let’s rebuild this from the inside out.