Kolie Moore

@SGamarad @jem_arnold I’m skeptical of many things in the above linked thread (needs more refs). Also skeptical that the methods in that paper are sufficient to really draw that conclusion.

@jem_arnold @type_iix I do wonder how Kolie would respond to Tomabechi 2018 because it really seems to put a damper on the whole idea.

This is a much better narrative thread on metabolic & performance implications of cadence, than my brute force attempt a while ago (see below) 👏

@jem_arnold I meant it as constructive. Check the last few Watts Doc episodes for info on aerobic adaptive pathways.

@type_iix Hah, well thanks I'll take that as constructive criticism to keep things simple.. I blame half formed questions and character limits and an allergy to brevity😅. Just looking for different ways to think so your responses are always appreciated 🙌

Are adaptations to mitochondrial content and/or respiration secondary to enhanced convective O₂ delivery? 🤔 Do mito start pulling more O₂ because we're pushing more O₂ at them?

@jem_arnold I dub thee “Jem Koan” because it always takes me a while to figure out what you’re actually asking, if ever 😅 in this case, haven’t a clue.

@type_iix oh maybe some simple answers in knee extension vs cycling exercise or 1-leg vs 2-leg research? Any differences between training with those modalities to peripheral mito content/respiration?

@jem_arnold @AndrewHires @JacobTipper @coachjorgem Individually the big factors seem to be the combination of muscle mass, pmax, and ftp (or whatever the buzzword dujour is).

@type_iix @AndrewHires @JacobTipper @coachjorgem Thanks. I wonder what the distribution is within that TTE range? Maybe the group mean works out but I wouldn't expect it to be reliable at individual level

At what duration of maximal exercise is the immediate energy contribution equally split ~50/50 between "aerobic" and "anaerobic" sources? (the calculations for this aren't super precise, but there are more correct and less correct answers. Let's get pedantic I'm here for it 😁)

@jem_arnold @AndrewHires @JacobTipper @coachjorgem A quick check of my rider data says 30sec to 4min is a ballpark TTE range for 2x ftp. I guarantee many of these would be way less than 50% aerobic on the shorter range. You asked a question that has an equation, not a number, as an answer.

@AndrewHires Ya, I dunno. I'd want to see data on that I wonder what the TTE range is at 2x FTP btwn riders? @JacobTipper @coachjorgem @type_iix Assumption of linear scaling that if TTE @ FTP = 100% aerobic ∴ TTE @ 2x FTP = 50% aerobic doesn't sound right to me🤔VO2 kinetics are non-linear

@BenjiNaesen Ask our mutual friend, it would be good to know how you measured 20w.

I bought an Assioma UNO power meter last year because it was famously accurate compared to other brands *cough* shimano *cough*. But suddenly, my Assioma's are overreading by like 20 watts right now and I can't seem to fix it. Calibrated them multiple times, crank length is correct. Any ideas?

@VanPinpin @LoosDieter @Domestique___ Observing a moment time in its own moment always has a shelf life. Like… Nobody’s saying media from when Carter was US president aged badly because he’s not anymore.

@LoosDieter @Domestique___ @type_iix Did not age well. finally not that badly maintained 😅 Human aspect, personnal balance and invidual specifities weight far more at the end of the week when you have the engine and so much cycling XP, rather than trying to apply book formulas and forget the basics

OPINION: 🇳🇱 Mathieu van der Poel should leave Alpecin-Deceuninck to become an even better rider. Look into this thread to find our reasons behind this opinion. Thoughts? 🧐

@stevemagness I guess I’m among the very few? Been harping on this for years in my podcast and just did a few episodes detailing these pathways. The conclusion being there’s no magic training and there’s no shortcuts.

What few tell you in the world of exercise: There are many pathways to the same adaptation. Want to increase mitochondria? Great... Activate CaMK through long slow training Or Activate AMPK through high intensity Or Hif-1 through hypoxia All end with PGC-1a --> mitochondria

@jem_arnold My coaching experience is the 30 has better endurance because the energy use is slower. But when things are no longer equal it’s impossible to tell who has better response to training the two different things at hand: muscular endurance vs cardiovascular capacity.

@type_iix Oh good one. It depends 😉 since at those different VO2maxes everything else is not equal. But let's say the higher abs energetic throughput athlete is limited first by total work. What then? Also very different to the longitudinal case of a 30 athlete becoming a 60 athlete?

What is the correlation between improvement in V̇O₂max and improvement in endurance performance? What are your favourite longitudinal data on that question?

@jem_arnold Thought experiment: two sedentary people with vo2max of 30 and 60, otherwise identical. Ride at 50% LT to exhaustion, who goes longer?

@type_iix Give some examples? What have you seen in your athletes over different timeframes, training methods, etc.?

@R_Behr @DrNathanT @jem_arnold @JohanTanman Now that I see what's up, the answer is so basic I'm a bit surprised a PhD hasn't run into it in the literature. Seems to be something that gets rediscovered once a decade or so.

@type_iix @DrNathanT @jem_arnold @JohanTanman 😅

2 athletes have the same 5MMP (a so called "measure" of MAP) + VO2max. Yet one achieves this with low CP / high W' and the other with high CP / low W'. Clearly one has superior MMSS but do they have the same MAP?

@R_Behr @DrNathanT @jem_arnold @JohanTanman Someone DM me screenshots I guess?

@R_Behr @DrNathanT @jem_arnold @JohanTanman Either someone's profile is private or I've been blocked, I can't see the thread.

@DrNathanT @jem_arnold @JohanTanman @type_iix do your thing please

@stevemagness Anyway, thanks for your podcast. Always a breath of fresh air.

@stevemagness Read this already, also not convincing. I'm skeptical that a fuel source is going to have anything close to the well studied effects that energy state, redox state, calcium, or hypoxia have.

One of my favorite workouts to boost aerobic abilities: 2x 5 miles @ marathon pace on hilly terrain. Hills throw some lactate into the system & cycles in different muscle fibers, but your pace stays under control so you learn to utilize lactate on flat portions.

@stevemagness I agree w/ 1's conclusion "...it is not clear yet how lactate affects these pathways; therefore, further research must be done to clarify the mechanism by which lactate is mediating...exercise-induced adaptations". They summarized speculative evidence. Not really a slam dunk.

@type_iix I get what you're trying to say...but: 1. Lactate acts as a good surrogate marker to things that activate pathways 2. There is research that shows lactate itself acts as a signalling molecule for exercise adaptations. See: ncbi.nlm.nih.gov/pmc/articles/P… and …ritionandmetabolism.biomedcentral.com/articles/10.11…

@HeWaHippo @doctorinigo Sorry, I can’t tell if the implication here is that lactate has a causal link to acidity or just association.

@type_iix @doctorinigo The rise of lactate causes the pH to drop which reduces glycolytic ATP resynthesis. Moreover, lactate synthesis only accelerates when phosphocreatine is roughly 50% down and low phosphocreatine concentrations are associated with a low deltaG of ATP hydrolysis and fatigue.

For almost 3 decades I’ve used the 7,000 rpm analogy to describe to athletes what’s like succumbing to ⬇️ muscle lactate clearance capacity due to mitochondrial impairment from excessive glycolytic flux during competition. Pyruvate accumulates and must be reduced to lactate which if not oxidized in mitochondria, it accumulates in the muscle with its Hydrogen ions… This great quote from the movie “Ford vs Ferrari” says it all..