biodude

@AlobhaPatrick @jordanticus Can you give and example and play it out

@xbiodude @jordanticus Conflict/ambivalence

Highly intellectualized (avoidance) you say? Psychoanalysis you say?

@jordanticus @AlobhaPatrick I wanted your perspective

@xbiodude @AlobhaPatrick Hopefully this helps: jonathanshedler.substack.com/p/are-you-gett…

@AlobhaPatrick @jordanticus What does the discrepancy mean?

@jordanticus @xbiodude And ask people what they want TO DO DIFFERENTLY and highlighting discrepancies between what they say they want vs. what they’re doing,

@jordanticus @AlobhaPatrick Can you dumb this down way further? Eli5?

@xbiodude @AlobhaPatrick When the therapy is mostly about identifying defenses and historical patterns and talking about theory, rather than interpretation of the transference in the here and now and integration of disowned aspects of the self. IOW you should really feel things in sessions.

@jordanticus @AlobhaPatrick What is “intellectualized” psychodynamic therapy?

@AlobhaPatrick Oh yes! Intellectualized psychodynamic therapy is bad therapy.

@Oakmanbearcow @CoffeeBlackMD Think you are the ones with the broken detectors

@CoffeeBlackMD You have a totally broken BS detector if you read Tucker as an honest guy.

I am surprised this post did any numbers at all. As I’ve said I have zero clue what gets noticed and it’s never what I think. It does look a bit like another hot stove topic. I post to chat with those silly enough to follow. I see Tucker like I see Rogan. Just men. They like conversations. They bring on people who interest them. Joe’s really stopped with anything too controversial. And I don’t blame him too much. He has people on occasionally or says things that drive me bonkers or I know is wrong. But I still love the guy. Probably haven’t heard a show of his in 6 months tho. Maybe longer. He’s basically harmless. Tucker I catch maybe once per month. Maybe twice. I skip his rambling monologues. I think he’s an honest guy. Prone to hyperbole at times? Maybe. But he tries very hard to be intellectually honest. It’s easy to tell. Which is different than necessarily being absolutely correct. He’s owned past mistakes. He painfully and annoyingly continues to separate out his criticism of something like the Israeli government from a big group of people we tend to colloquially call the Jewish people. He clearly doesn’t hate anyone. He’s disagreed with Trump or “maga” on a number of big points. Outlined why. I have sympathies there. And I think he’s correct. So I guess that’s what looks like the big problem is. With him. He has a big enough audience the arguments underlying his disagreements get inconvenient market share. Plenty of people either consider them or agree because they’ve come to the same pretty clear conclusions. The rest. That I saw brought up were almost all bonkers conspiratorial, incorrect, baseless, or post hoc rationalizations. They are in the replies there. And the “antichrist” bit? Omg. He wouldn’t participate in the struggle session framing. It’s all so intellectually dishonest. Also if you seem to have no respect for Christianity. Poke fun at it. Use images sacrilegiously or cynically, that is something an antichrist might do (1 John 2:18). Is it something THE Antichrist would do? Sure. The rhetorical statement was provocative but instead of contemplating on it, many decided to simply sh*t directly into their pants about it. Aliens and demons. It’s wild. But it’s also internally consistent. The occult and the new agey alien stuff have a lot of uncomfortable overlaps. Like changeling. And symbology. There’s a lot we don’t know about the great controversy between good and evil. And that can all exist outside of a UAP phenomenon. It might be tough to walk and chew gum here. But I can and I’m fine with it. Tucker’s just a dude, guys. Don’t make him more (or less) than he is. And chill. Seriously.

@chrislakin Is it the asian guy who hosts hot pot parties now

@xbiodude there’s a lot of guys I talk about

a guy I know has gone from being invited to things once every few months to 3x a week. he hasn't (consciously) changed anything about how he socializes

@webdevMason @DavidDeutschOxf What do you think about this now?

@DavidDeutschOxf I think destination-focus is often preferable to path-focus because it (a) gets you closer to thinking about desires & (b) gives you a reference point, coordinates that you can notice yourself moving closer to or further from. Still, the failure mode you're noting is very real

Another layer: people think the problem is "taking the easy path." That's not the problem! The problem is not *fully defining any desires* that don't already have a well-trodden path to their satisfying condition, never allowing them enough weight to fall out of the clouds twitter.com/webdevMason/st…

@GeringerAdam @regard_capital They’re asking for the opposite of what you just did

@regard_capital The male equivalent of this photo reads as performative or secretly indian. Imagine it’s a muscular hand with a Rolex oyster on a Porsche wheel

It’s crazy you can tell a girl is probably smoking hot just based on a random photo like this

@mrswamsbsgans @SandySandsickle Why?

@SandySandsickle and i would've loved for her to say it but it makes more sense for shiv to let him think she dgaf

a lesser show would’ve had tom and shiv having these insane fights twice a season but succession was so good at blue-balling you until you were aching for catharsis and then it finally happened and you just felt like shit

@CoffeeBlackMD @AbudBakri Dude those are long wake periods, are you up doing something?

It’s been a week. 6mg every morning. I had a couple shit nights on Friday and Saturday that were my fault. But the trend of MORE deep sleep for me continues. I used to have REM dominant sleep with some REM even showing up earlier. And now I’m seeing the DEEP predominant the first part of the night. Dreams have not been more vivid. These have been my normal dreams. BUT REM is happening in LONGER chunks. Which is also interesting. I may be a “REM heavy” sleeper? Not sure why the REM is architecturally clumping. I think I’ve seen @AbudBakri talk about this in the past but I’ve not had the time to dig into it.

@CoffeeBlackMD That’s pretty wild actually, as someone who struggles to get high quality deep sleep

First night. DEEP longer than my usual which is often 45-60m. I’m wearing the tracker this week. And I’ll see if last night was an outlier. Can’t make too much of one night. But it did raise my eyebrows this morning.

@owl_posting @olek_bio Same here!!

@olek_bio dm’d!

spent months futzing around with lifestyle habits + supplements + 8sleep to no avail, and then finally asked a doctor if there is any side-effect free miracle drug to fix this. turns out there is and im cured. claude never suggested it. i am setting my agi timelines back a year. i am so, so, so grateful for the pharmaceutical industry. raise the drug prices

@anthonystaj ir.sana.com/news-releases/…

genuinely don't know what you mean lol i told you what i meant by "preservation" and what i meant by "not SANAs program". it isn't their actual clinical molecule. Carl June doesn't claim every CAR-T program ever made. CEO said it wasn't their final molecule the other day on Biotech TV, seems like they may have some more edits added beyond this first patient. i find it uninspiring because we only have data from one patient! T1D is a very heterogeneous disease, some patients take a long time to progress. how do we know where this patient sits on that spectrum? i also want to see the IND and ph1 start before i take it all too seriously

remember when $SANA mooned on a swedish collaborator releasing n=1, 28d, c-peptide preservation data from their own (not SANAs therapy) islet replacement program? $sabs shows us today they actually INCREASED c-peptide (not just preserved it) in their T1D cohort from the ph1

@anthonystaj The entire purpose of that experment was to prove the immune evasion of the platform. This is a holy grail for allogeneic cell therapies. They cracked one of the major problems necessary. They do not appear to need any “design” work. They need cells which match the design now.

@anthonystaj Second, it’s not their final “molecule” because they haven’t finished making the master cell bank. As much as they’re claiming progress, there is plenty of room to be skeptical there on the actual cell development and manufacturing. That’s a massive challenge. BUT

@anthonystaj First, I think you’re confused by preservation perhaps because you’re thinking about progressive decline of endogenous function or something. Irrelevant in this case. This patient has no endogenous function. The new cells provide all c-peptide observed.

@anthonystaj Yet somehow, they’ve transplanted pancreatic cells from a dead person into a person with T1D whose immune system has already destroyed their own pancreas, and in the absence of immune suppression those cells are alive a month later and churning out c-peptide

@xbiodude do you know how T1D works? the pancreas gets "rejected" by the body

@anthonystaj No shit.