Wei Lab@wisc

656 posts

Wei Lab@wisc

Wei Lab@wisc

@Wei_Lab_WISC

Wei Lab in the Biochemistry Department at the University of Wisconsin–Madison @UWBiochem https://t.co/h7olsIYTNl

Entrou em Mayıs 2020
1.1K Seguindo1.4K Seguidores
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Long Lab
Long Lab@longlabstanford·
The first approved GLP1 (Byetta) came from a desert reptile, the Gila monster. Inspired by this, our work on Burmese pythons 🐍🐍 is now out @NatMetabolism. An “extreme”-ly fun collaboration with Leinwand and @DrYongXu1. Congratulations @Shuke_Xiao! nature.com/articles/s4225…
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Wei Lab@wisc retweetou
Long Lab
Long Lab@longlabstanford·
A first in class PTER inhibitor exhibits anti obesity activity (in mice)- and importantly, via a mechanism distinct from, and additive with, existing GLP1-RAs. Fun collaboration with Gray lab now out @CellChemBiol. Congratulations team! @Stanford_ChEMH cell.com/cell-chemical-…
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Wei Qin
Wei Qin@WeiQinChemBio·
Excited to share our new preprint on Hi-APEX — a truly H2O2-independent proximity labeling method! We discovered a new probe, tetrazine-phenol, which enables APEX2 labeling without needing exogenous H2O2. Best part? No changes to the APEX2 enzyme are required.
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Shan He
Shan He@Shan_He_lab·
Our paper is online today! 🎉 We identify a key regulator of the pyrenoid condensate. Thanks to an amazing Princeton-based collaboration! I have greatly enjoyed working with everyone. nature.com/articles/s4155…
Princeton MolBio@PrincetonMolBio

Today in Nature Cell Biology, a collaborative effort across labs (Jonikas, Wingreen, Brangwynne) at Princeton discovers the key to regulating a biomolecular condensate. Congrats to first authors Shan He and Linnea Lemma! molbio.princeton.edu/news/2026/key1…

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Xin Jin, PhD
Xin Jin, PhD@xinjin·
Today, I am thrilled to introduce @PerturbAI_Tx, a company I co-founded to rethink drug discovery. Biology is complex, and disease unfolds across genes, cell types, and tissues. We’re powering AI with the causal logic of human genetics: perturb.ai
Perturb.ai@perturbai_tx

Introducing PerturbAI. Today we announced our emergence from stealth with the release of the world’s largest in vivo CRISPR data engine, interrogating the effects of thousands of genetic perturbations across 8 million cells throughout the whole brain. This dataset represents a new category of biological data: organism-level, circuit-resolved causal genomics leading to novel targets and therapeutics. By combining scalable in vivo CRISPR perturbation with AI, we model biological systems at unprecedented resolution and simulate therapeutic interventions before committing to expensive downstream development. We’re grateful to our collaborators at @NVIDIAHealth and @10xGenomics for helping make this landmark dataset possible. Read More: perturb.ai/news #CRISPR #AI #DrugDiscovery #FunctionalGenomics #Biotech

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Lamming Lab
Lamming Lab@LammingLab·
In this terrific publication, Dr. Reji Babygirija shows that restriction of dietary leucine or isoleucine in males, and restriction of valine in females, preserves cognitive function in a mouse model of AD advanced.onlinelibrary.wiley.com/doi/10.1002/ad…
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Lamming Lab
Lamming Lab@LammingLab·
Please enjoy the latest publication from our lab "Restriction of Individual Branched-Chain Amino Acids has Distinct Effects on the Development and Progression of Alzheimer's Disease in 3xTg Mice"
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Wei Lab@wisc
Wei Lab@wisc@Wei_Lab_WISC·
A great lab & PI!
Chris Zimmerman@ZimmermanNeuro

📢📢My lab at @UUtah is officially open and I'm RECRUITING — especially techs/specialists and postdocs! Our research focuses on the neurobiology of interoception and learning/memory using tools from systems/comp neuro. Please share!🧠🏔️🏜️ Apply/more info: #positions" target="_blank" rel="nofollow noopener">zimmerman-lab.org/#positions

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Keren Hilgendorf
Keren Hilgendorf@Hilgendorf_Lab·
University of Utah, Center for Metabolic Health (CMH), Postdoctoral Rising Stars in Metabolism, Sept 2nd, 2026 If you are a postdoc with an exciting METABOLISM story, apply using the QR code by April 24th. Please share with your colleagues.
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Lingjun Li
Lingjun Li@LingjunLi2·
Grateful and honored to receive this award honoring Cathy who has been a great mentor, role model, and inspiration throughout my career. Huge congratulations to all awardees! Grateful for the @us_hupo community, inspired by the science, and thankful for the people.
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Lingjun Li Research Group@LiResearch

Congratulations to our PI @LingjunLi2 for winning the Catherine Costello Award for Exemplary Achievements in Proteomics at the @us_hupo Conference 🥳🥳🥳

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Wei Lab@wisc retweetou
Long Lab
Long Lab@longlabstanford·
GLP-1 drugs transformed obesity treatment. But they don’t work for everybody. What else regulates body weight? In 2024, we linked the BMI-associated enzyme PTER to a non-GLP-1 pathway. Now: first-in-class PTER inhibitors with efficacy in mice. Link here: biorxiv.org/content/10.648…
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Vatsan Raman
Vatsan Raman@vatsanraman·
Phages shape microbial ecosystems on Earth—but what about in space? In our new study, we show that microgravity aboard the International Space Station reshapes phage–bacteria interactions, evolution, and fitness—with surprising benefits for targeting resistant pathogens on Earth. Great work @phil_huss @chuchitboonthav @RhScientific journals.plos.org/plosbiology/ar…
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Wei Lab@wisc retweetou
Long Lab
Long Lab@longlabstanford·
Most people eat small (~1-2% body weight) and frequent (2-3x/day) meals. But Burmese pythons 🐍🐍 can fast for >1 yr and eat 100% of their weight in a single meal. What happens in snakes after eating? What lessons they can teach us about human physiology? biorxiv.org/content/10.648…
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Lamming Lab
Lamming Lab@LammingLab·
Pleased to announce the publication of talented postdoc Dr. Yeh @iCCup_Spec new paper "Ketogenesis is Dispensable for the Metabolic Adaptations to Caloric Restriction"!
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@NatMetabolism @DrYongXu1 @Shuke_Xiao @CellChemBiol @Stanford_ChEMH @GuonHuang @XiaoxinChen2024 @PNASNews