Greg Yang

I've been suffering from Lyme disease. I'm stepping back from xAI into an informal advisory role so I can go founder mode on my health, starting today. --- The symptoms started when I got sick (cold, flu, or COVID -- I'm not sure which) in early 2025. I distinctly felt less energetic, less creative, and less agentic even weeks after "recovery." After that, my condition ebbed and flowed, but the lows kept getting lower. Accidentally eating the wrong thing would make me extremely tired, taking days to recover. Working out would leave my whole body feeble for days. There was a week where I slept 12 hours a day and still couldn't recover. Lyme is famously hard to diagnose, but luckily I have an incredible doctor. He suspected these symptoms, far from being just in my head, indicated immune issues. Detective work over a few rounds of testing revealed I have Lyme disease. I was very surprised because Lyme is said to come from tick bites (where the bump looks like a target), but I don't ever remember having one. Likely I contracted Lyme a long time ago, but until I pushed myself hard building xAI and weakened my immune system, the symptoms weren't noticeable. --- Overall, I actually feel lucky to have discovered this early. Lyme is a serious disease that only gets harder to treat with age -- patients discovering it in their 50s or 60s have a much tougher time. Lyme can also be debilitating, leaving its victims bedridden, but luckily I'm still functional and can take care of myself day to day. So while some folks have said "you shouldn't have pushed yourself so hard," I'm glad I did. I found this issue early, and now I can fix it so I can push myself even harder when I rebound. --- Chronic Lyme is not well understood in the literature or by the public. For folks suffering from it, it can be a lonely fight. But I hope my story can make it just a little less lonely.

my brain's oxygenated better during sleep now! my apnea-hypopnea index AHI has gone down dramatically from 25.4 (last September) to 4.6 😁 the AHI detects the number of apnea or hypopnea events per hour of sleep: - an apnea event is a period of no breathing for at least 10 seconds - a hypopnea event is a period of shallow breathing my blood oxygen saturation can still dip to 87% so not perfect yet if i were to guess, most of improvements came from - better nutrition and losing lots of weight - sleeping in colder room and maybe - cavitation surgery that cleared up my sinus I don't think this will cure my lyme but should help stabilize the condition and allow me to recover faster with fewer set backs

the funniest thing I'm sensitive to is black paint, especially on metal not sure what the chemistry is or if only the most common black paint is bad but it will easily make me fatigued being around it 1. once I bought a simple black metal shoe rack from target and it completely polluted the air around my entrance 2. I bought a standing desk where the legs are black metal. I could feel stress and a tiny anxiety when taking standing meetings next to it. But I feel ok as soon as I move away from it 3. I bought a stool with black legs. When I sit on it my legs feel funny and inflamed 4. Part of my door's lock is in black paint and I feel a blip in energy every time I enter or exit 5. my old hamper is black and I feel a bit ill around it 6. the small magnet in my inner shower curtain is black and when I sit on the toilet I'm right next to it and feel bad. Pushing the curtain away from me feels better. suffice to say I got rid of any black paint in my place now

turns out I can get very fatigued if I stand for too long but walking is fine so now I just march in place while I'm cooking and it really works 😅

rest in pieces my granny she got hit by a bazooka

broccoli is just so good man

Josephine had a generational immune system

@JustinPerryPhD what's your lyme hypothesis?

@TheGregYang Interesting re butyrate. We found that butyrate enhances efferocytosis (clearance of dead cells & debris, essential for all tissue function, normal turnover, & homeostasis). We also show how antibiotics disrupt this. Sadly, no $ for Lyme hypothesis we have tinyurl.com/mrytfeya

my energy in the past month: slow, fluctuating progress! observations: - past week I had 2-3 consecutive days of good energy! then crashed a bit :( - I'm "crashing" like every 3-4 days on average, but that's lengthening - the stack of butyrate + omega-3 plasmalogen + phosphatidylcholine can reliably pull me out of a 5 into 5.5-6 range what the numbers mean: - 5 is like tired and I'd rather stay in bed but can force myself to do things if I have to - 6 is like I can do things I need to but my brain is kinda empty and slow - 7 is like I don't feel any resistance to do the things I need to do - 8 is like that but my brain is running noticeably faster than 7

crash fixed by butyrate + omega-3 plasmalogen + phosphatidylcholine

@darthur self report

@TheGregYang Do you subjectively rate your energy level each day, or is this informed by passive data trackers?

good news: i can replicate crashing with the NASA lean test (you lie down for 10 min then lean against the wall for 10 min) bad news: im crashing

be careful about blueberry skin I've long felt blueberries's anti inflammatory effect but also an inflammatory effect at the same time (they don't cancel out) today finally I cut some open and ate only the flesh --- voila purely anti inflammatory when i ate the skin itself it's purely inflammatory not sure why but potentially pesticides

@miniapeur lots seed oil, gluten, dairy, eggs but I tested for allergies for gluten, dairy, eggs

@TheGregYang I never paid any attention to mercury in my food. Have you found other type of food that makes you tired?

wow eating swordfish actually makes me tired the high mercury is no joke

should I pull a @bryan_johnson here

@ShamKakade6 Haha yessirrr

@TheGregYang @TheGregYang best of luck getting better! And we have more planks to do when u are back to full health! ❤️

I've been suffering from Lyme disease. I'm stepping back from xAI into an informal advisory role so I can go founder mode on my health, starting today. --- The symptoms started when I got sick (cold, flu, or COVID -- I'm not sure which) in early 2025. I distinctly felt less energetic, less creative, and less agentic even weeks after "recovery." After that, my condition ebbed and flowed, but the lows kept getting lower. Accidentally eating the wrong thing would make me extremely tired, taking days to recover. Working out would leave my whole body feeble for days. There was a week where I slept 12 hours a day and still couldn't recover. Lyme is famously hard to diagnose, but luckily I have an incredible doctor. He suspected these symptoms, far from being just in my head, indicated immune issues. Detective work over a few rounds of testing revealed I have Lyme disease. I was very surprised because Lyme is said to come from tick bites (where the bump looks like a target), but I don't ever remember having one. Likely I contracted Lyme a long time ago, but until I pushed myself hard building xAI and weakened my immune system, the symptoms weren't noticeable. --- Overall, I actually feel lucky to have discovered this early. Lyme is a serious disease that only gets harder to treat with age -- patients discovering it in their 50s or 60s have a much tougher time. Lyme can also be debilitating, leaving its victims bedridden, but luckily I'm still functional and can take care of myself day to day. So while some folks have said "you shouldn't have pushed yourself so hard," I'm glad I did. I found this issue early, and now I can fix it so I can push myself even harder when I rebound. --- Chronic Lyme is not well understood in the literature or by the public. For folks suffering from it, it can be a lonely fight. But I hope my story can make it just a little less lonely.

> Aliens (1986) > be companyman rallying a troop to defend humans from aliens in off world planet > betrays everyone to bring aliens back alive as bioweapons and obtain generational wealth > looks like sam altman

if you don't have this question in your eval set, you NGMI