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BoelLab
330 posts
BoelLab
@BoelLab
Our principal interest is to understand the fundamental aspect of protein synthesis mechanisms and regulations.
@ibpcF Paris, France เข้าร่วม Şubat 2019
229 กำลังติดตาม226 ผู้ติดตาม
Looks super cool, can’t wait to try it
Sergej Djuranovic@DjuranovicLab
Collaborative work of @slavicaPD, @Hashemyaser4, Jovanovic Lab and @DjuranovicLab - a new method to isolate ribosomes and translational material in minutes. We show multiple usage of our RAPPL method in biochemical and structural assays with ribosomes. Please be free to contact us for further instructions if needed. @IsraelF96135088 you'll like this one. A rapid, facile, and economical method for the isolation of ribosomes and translational machinery for structural and functional studies biorxiv.org/content/10.110…
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Check out this amazing ribosomes purification method from virtually any cell type or bacteria, works in matter of minutes from infinitely small quantities 🤯🤯🤯.
From @slavicaPD and @DjuranovicLab
Thanks for the letting me part of this work, was fun to be your consultant 🤓
Sergej Djuranovic@DjuranovicLab
Collaborative work of @slavicaPD, @Hashemyaser4, Jovanovic Lab and @DjuranovicLab - a new method to isolate ribosomes and translational material in minutes. We show multiple usage of our RAPPL method in biochemical and structural assays with ribosomes. Please be free to contact us for further instructions if needed. @IsraelF96135088 you'll like this one. A rapid, facile, and economical method for the isolation of ribosomes and translational machinery for structural and functional studies biorxiv.org/content/10.110…
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BoelLab รีทวีตแล้ว
Our timely contribution to the growing body of YebC2/TACO1 literature 🤩! YebC2 is a third factor that prevents ribosome stalling at prolines. Associates with 70S and important for fitness in absence of EF-P and YfmR.
biorxiv.org/content/10.110…
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BoelLab รีทวีตแล้ว
Activity, structure, and diversity of Type II proline-rich antimicrobial peptides from insects | EMBO reports embopress.org/doi/full/10.10…
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BoelLab รีทวีตแล้ว
This is really a stunning paper.
Cyanobacteria exposed to shorter days (in the lab) "rewire" their membrane lipids to anticipate cold weather.
When those cells are plunged into cold water, they have "two or three-times higher survival" than cells exposed to longer days.
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BoelLab รีทวีตแล้ว
Our collaboration with @WilsonLab2 and @vpelech is out in @NAR_Open! The ABCF ATPase New1 resolves translation termination defects associated with specific tRNAArg and tRNALys isoacceptors in the P site
academic.oup.com/nar/advance-ar…
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BoelLab รีทวีตแล้ว
Congrats to @biozentrum @snsf_ch Ambizione Group Leader @FlorentWaltz on this stunning study🤩 of respirasome structure & organization inside native cells! It's amazing how quickly in situ #cryoET is advancing. Read Florent's thread🧵 for the high-resolution details🔎🦠 #TeamTomo
Florent Waltz@FlorentWaltz
Super excited to share our latest work on the native in-cell organization of the mitochondrial respiratory chain 🥳 Using cryo-electron tomography🔬, we show how the respiratory complexes (and other complexes) are organized inside native mitochondria! biorxiv.org/content/10.110…
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BoelLab รีทวีตแล้ว
Principal Investigator @gagnon_lab and researchers at @utmbhealth use cryogenic-electron microscopy to elucidate the mechanism of GDP dissociation from RF3 catalyzed by the Escherichia coli 70S-TC. buff.ly/4dxEqwm
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BoelLab รีทวีตแล้ว
Tour-de-force by @Jonatha31791089 enabling visualization of protein folding within cells by cryo-ET. Great collaboration with @MPI_Biochem colleagues, just out @Nature rdcu.be/dRAQ8
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BoelLab รีทวีตแล้ว
Here, Koch lab reports on bacterial ribosome hibernation. They show that the membrane-tethering hibernation factors YqjD/ElaB/YgaM, discovered by Wada in E. coli, are widely conserved in proteobacteria and likely target the ribosomal peptide tunnel👍
biorxiv.org/content/10.110…
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@Hashemyaser4 @TBioc @OusalemF @CNRS @IbpcF @univ_paris_cite @EGM Yes finally, that wasn’t as easy as expected 😉
Thanks Yaser
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Very happy to announce that our paper “Global regulation via modulation of ribosome pausing by the ABC-F protein EttA” has been published nature.com/articles/s4146…. Congratulation to all the lab members and especially the first authors @ousalemF
@CNRS @IBPCF @univ_paris_cite @EGM
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BoelLab รีทวีตแล้ว
Out now in @PNASNews we used Tn-seq to identify genetic interactions with EF-P in B. subtilis. We found that 1) the ABCF YfmR (Uup) is required in absence of EF-P in some conditions
pnas.org/doi/10.1073/pn…
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