Carette Lab

Finally! It is happening! After 6 years of hard work by formidable teams in 13 institutions @RESOLUTE_IMI, we have ordered and validated the results and are able to share the FOUR (4) papers aimed at assigning functional properties to each human SLC #membranetransporter

Introducing new #ProgramLeaders! Meet Lily, a 4th year PhD candidate in the #MicrobiologyandImmunology. With a BS #biomedicalengineering and #computationalbiology from @WUSTL, she studies host-pathogen interactions by characterizing viral proteins and host factors using cryo-EM

Tenure Day 🎊! I am incredibly grateful to all the Wang lab members who form a thoughtful, dynamic, and motivating team. Time to celebrate!

Thrilled to see our paper "A Proximity Proteomics Pipeline with Improved Reproducibility and Throughput" published! It describes the automated enrichment of biotinylated proteins in a 96-well plate format for spatial proteomics and protein interactions. embopress.org/doi/full/10.10…

Check our recent publication about how the antibody response to Omicron-based boosters in humans is imprinted by immunizations with historical mRNA-1273 vaccines. Congrats to Chieh-Yu! #WUSM #COVID nature.com/articles/s4158…

Congrats to Wenjie & team! Excited to share the the work entitled, "MYADM binds human parechovirus 1 and is essential for viral entry" that was published in Nature Communications today. Credit to all authors!  nature.com/articles/s4146…

Interested in small RNA viruses ? Come work with us. Contact us and we will help you through the application! …sklodowska-curie-actions.ec.europa.eu/node/1258

Congratulations to lead author @WenjieQiao and collaborators Chris, Youlim, @JamesZengel, @sding88, and Harry.

Excited to shared our latest manuscript describing the discovery of a receptor for parechoviruses rdcu.be/dFTMO. Parechoviruses belong to the same family as poliovirus and are increasingly linked to neurological disease. (1/2)

Fantastic opportunities in a super exciting young lab! (And the neighbors are nice too) 👇

Applications are open for the 2024 Stanford Summer Research Program (#SSRP). 📝 #SSRPAMGENScholars are fully-funded, on this research-intensive, eight-week summer journey taking place on @Stanford’s campus 💡 Learn more at ssrp.stanford.edu. Apply by February 1st, 2024

Deep sadness over @BrettLindenbach’s passing 💔 His love of virology was truly inspiring. Please consider supporting Brett’s legacy by contributing to the Brett Lindenbach Virology Fund, to help train the next generation of scientists in virology. medicine.yale.edu/news-article/t…

We will miss you Brett. ⁦@BrettLindenbach⁩ legacy.com/us/obituaries/…

Please share! We're recruiting a tenure-track junior faculty member to join our Institute Scholar community at Sarafan ChEM-H @Stanford! We encourage applicants working at the interface of science, engineering, & medicine to apply: stanford.io/3PXaznX

Check out this work from our lab on genome-wide single-gene CRISPR/Cas9 knockout screens to comprehensively interrogate CFTR- F508del ERAD. biorxiv.org/content/10.110…

We love genetic approaches to define virus:host interactions. Knockout screens are powerful, but...technical constraints limit what you can find. Could we devise a screen where viral fitness pinpoints the key regulators of replication? (spoiler - yes cell.com/cell-host-micr…) 1/10

If you like #genetics in human cells you may enjoy our latest paper by @itsgianluca and collaborators. A ‘fishing expedition’ using logic as our guide by Gian-Luca McLelland to study triglyceride synthesis. After some plot twists it yields DIESL! nature.com/articles/s4158…

Congratulations to Professor Ann Palmenberg, who retires this week after more than 40 years @UWBiochem & @MadisonVirology! Palmenberg built her lab & career around unveiling the enzymes & mechanisms responsible for controlling viruses. Her research established the foundation ➡️

I had the pleasure to review the lysosomal enzyme trafficking pathway and its role in genetic diseases, cancer and viral infections with two leading experts, Thomas Braulke and Jan Carette @CaretteLab for @TrendsCellBio. You can access the article here: authors.elsevier.com/a/1hRTA3QxxSr7…

Excited to share our labs first @Nature paper! In collaboration with @VintherLab we show that hepatitis C virus #RNA is capped with FAD protecting it from innate immune sensing. rdcu.be/df8p5 Congrats Anna Sherwood and Lizandro Rivera-Rangel 👏🏻🍾 #HCV @UCPH_health