FeigeLab

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FeigeLab

FeigeLab

@FeigeLab

Translational research on Muscle and Aging biology / NIHS Nestle Institute of Health Sciences / @EPFL Ecole Polytechnique Fédérale de Lausanne

Lausanne, Suisse เข้าร่วม Haziran 2019
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FeigeLab
FeigeLab@FeigeLab·
Exciting translational publication just out @jclinicalinvest on a nutrition screen for #stemcells, #muscle #regeneration and #Aging. Fantastic work from our ex @epflSV student @SaraAncel & great collaborative team from Nestle R&D 🧫💪🏃‍♂️
Sara Ancel@SaraAncel

Excited to share the discovery of nutrients that stimulate MuSCs during #Aging in @jclinicalinvest 🎉 Very grateful to all fantastic teams @RemiRmounier @GondINMG @Isabscionti and stellar colleagues JorisMichaud PascalStuelsatz @FeigeLab 🙏 #myotwitter jci.org/articles/view/…

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FeigeLab
FeigeLab@FeigeLab·
📣important perspective: while pre specified clinical endpoints are key for hypothesis validation, open clinical exploration for hypothesis generation in humans should also be encouraged, especially to understand molecular physiology 💪🏃‍♀️
Abigail Mackey@AbigailMackey1

We wrote this letter to address the overly rigid preregistration requirements imposed now by many journals on exploratory experimental physiology research - time to align guidelines with contemporary research methods! @proferikrichter @ISMCopenhagen physoc.onlinelibrary.wiley.com/doi/10.1113/EP…

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Matthew S. Alexander
Matthew S. Alexander@Matt_Muscle_Guy·
It is that time again, time to vote for the 12th Annual Matt's Totally Biased (but less so) Top 10 Muscle Papers of the Year. Due to prohibitive shipping costs, this year’s winner will receive an e-gift card in lieu of a plaque. Voting will end Dec. 20. uab.co1.qualtrics.com/jfe/form/SV_51…
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David J Glass MD
David J Glass MD@davidjglassMD·
Just a reminder as to the mechanism of action of Bimagrumab, and it's origins ;-). An Antibody Blocking Activin Type II Receptors Induces Strong Skeletal Muscle Hypertrophy and Protects from Atrophy. pmc.ncbi.nlm.nih.gov/articles/PMC39…
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The Hornberger Lab
The Hornberger Lab@HornbergerLab·
1/10 Excited to write this thread summarizing our new paper in @NatMetabolism, which identifies a potentially critical part of the signaling pathway that drives skeletal muscle growth in response to resistance exercise! Free link rdcu.be/el9am #Myotwitter @NIH_NIAMS
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Shukry J Habib
Shukry J Habib@ShukryHabib_Lab·
Join us in Lausanne 🇨🇭 for the Lac Léman Regenerative Medicine Symposium, Sept 17–19, 2025! 🔬 Stem cells, aging, bioengineering — shaping the future of regenerative medicine. habiblab.org/l2rm 🎟️ Students 25 CHF | Postdocs/Faculty 50 CHF | Industry 150 CHF #L2RM
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Nature Aging
Nature Aging@NatureAging·
Online now!✨RESEARCH: using multi-omics analysis of patient samples, Zuo et al link disrupted BCAA catabolism to sarcopenia. In mouse models, they demonstrate that enhancing BCAA catabolism protects against sarcopenia nature.com/articles/s4358… rdcu.be/d9SFw
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FeigeLab
FeigeLab@FeigeLab·
Converging results on impaired mitochondrial calcium as new hallmark of #aging in neurons and skeletal muscle 🧠 💪 cell.com/cell-metabolis…
Science Magazine@ScienceMagazine

New findings in mice have uncovered a crucial mechanism linking neuronal activity to mitochondrial function, researchers report in Science, revealing a potential pathway to combat age-related cognitive decline. 📄: scim.ag/3DjdseC #SciencePerspective: scim.ag/4gZZMEb

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FeigeLab
FeigeLab@FeigeLab·
A message to relay: Sarcopenia is not just any sort of muscle wasting, its the loss of muscle mass AND strength with old age (different from cachexia secondary to cancer/COPD/CKD/CHF or disuse atrophy during immobilization…)
Prof Omid Khaiyat M.D., PhD@Omid_HopeUni

Sarcopenia ≠ low muscle mass Main differences between causes, dysfunctions, and outcomes associated with sarcopenia and low muscle mass👇 #muscle #sarcopenia #Health link.springer.com/article/10.100…

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LongCovidRD
LongCovidRD@longcovidRD1980·
@EricTopol @jclinicalinvest @mattiaquattro Important not to be deficient in B6, but both deficiency and toxicity can cause irreversible neuropathy. Mayo Integrative doc said no more than 25mg B6 total for the day. Lots of B-supplements have 100+mg. 🌞
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@ScienceMagazine @BrendanEvano @NatMetabolism @NatureComms @Nature @NatureAging @davidjglassMD @NIH_NIAMS