GESTALT

1/ The need for a Global Alliance for Spatial Technologies arises from multiple driving factors, pushing the progress and use of spatial tech across various disciplines. #GESTALT

#STAMP super cool video by Càtia Moutinho from the Single Cell World 🫶 open.substack.com/pub/thesinglec…

Spatial Stage - The Festival of Genomics Biodata & AI 2026 In a new collaboration between Festival Of Genomics (@FLGenomics) and @GESTALT_sp…we have crafted the Spatial Stage bringing to you the most exciting advances in spatial biology. I will miss out Boston (yeah, I know…) but my out-of-the-chart-amazing co-founders @ioavlachos and @DrJasPlummer as well as the one and only friend and family member @katycns will be here to welcome you all. festivalofgenomics.com/boston/explore…

#AGTA2026 returns to Sydney (Roundhouse UNSW), Sept 1316! Confirmed superstar speakers: Braden Tierney Jiwoon Park Martin Smith Lipin Loo Tiffany Boughtwood Justin Wong Joseph Powell Kim-Anh Lê Cao Topics: Population-scale genomics (clinic + non-human) Spatial and Sc omics, disease atlases CRISPR, functional/regulatory genomics AI for genomics and pathology Emerging platforms and automation #AGTA2026 #Genomics #SpatialOmics #CRISPR #SingleCellOmics #AiGenomics #FunctionalGenomics #ClinicalGenomics @agtaGenomics

Hack alert! 🚨 In vivo multiomic Perturb-seq with enhanced nuclear gRNA capture | bioRxiv biorxiv.org/content/10.648…

Hello single cellers and also spatial people! The Single Cell Ninjas are back on the road and would like to offer 1:1 tele-consultations sessions to discuss experimental designs, technologies choices, troubleshooting and so on. All completely free of charge. Please DM us!

This is cool 😎 I would love to try it out as well. Congrats to @AtlasXomics @UltimaGenomics @WatchmakerGeno1 and Prof. Matija Snuderl on this amazing technology !!!

Check out this important advance in mitochondrial 🧬 lineage tracing by @tGaoTeng and @chenweng1991 from our group, in collaboration with @JswLab 👇👇

Join me and these 4 super legends in the fields of single cell and spatial‑omics for a fast‑paced discussion on innovative benchmarking approaches that address delivering the deepest biological insights per dollar, tailored to your specific study design.

𝗕𝗲𝗻𝗰𝗵𝗺𝗮𝗿𝗸𝗶𝗻𝗴 𝗶𝘀 𝗕𝗿𝗼𝗸𝗲𝗻. 𝗟𝗲𝘁’𝘀 𝗙𝗶𝘅 𝗜𝘁. Single-cell and spatial benchmarking studies dominate journals and conferences. Yet, after the leaderboards are published, you’re still left with the same high-stakes questions: Do these metrics actually inform your next biological move, or just confirm what you already know? When the grant money is on the line, the question isn't just 'what works' - it’s 'what works within reach.' Which platform truly maximizes biological output for your specific budget? Most benchmarking work misses the point. It ranks tools. It crowns winners. But it leaves you to carry the risk when it’s time to design your study and spend your grant. 𝗠𝗼𝘃𝗶𝗻𝗴 𝗕𝗲𝘆𝗼𝗻𝗱 𝘁𝗵𝗲 𝗟𝗲𝗮𝗱𝗲𝗿𝗯𝗼𝗮𝗿𝗱 At AGBT 2026, four of our beloved leaders in the field will challenge the status quo of benchmarking. We aren't talking about which method "wins" or who runs the fastest pipeline. We are questioning the utility of the metrics themselves. This discussion will dive into the hard truths of study design: -𝗜𝗻𝘀𝗶𝗴𝗵𝘁 𝘃𝘀. 𝗠𝗲𝘁𝗿𝗶𝗰𝘀: are you optimizing for biological discovery or just "clean" data? -𝗥𝗲𝗮𝗹𝗶𝘁𝘆 𝘃𝘀. 𝗜𝗱𝗲𝗮𝗹𝗶𝘀𝗺: are you planning studies real labs can afford, or chasing extreme depth that isn't reproducible? -𝗚𝘂𝗶𝗱𝗮𝗻𝗰𝗲 𝘃𝘀. 𝗛𝘆𝗽𝗲: are benchmarks helping you design better experiments or simply feeding a hype cycle? 𝗝𝗼𝗶𝗻 𝘁𝗵𝗲 𝗖𝗼𝗻𝘃𝗲𝗿𝘀𝗮𝘁𝗶𝗼𝗻 If you generate or analyze single-cell or spatial data, this panel will speak directly to your results and your bottom line. Details coming soon. Stay tuned! #Benchmarking #SingleCell #MultiOmics #Bioinformatics #Genomic #SpatialBiology #AGBT2026

London and euro peeps excited to see you tomorrow!!! . A spatial stage for the first time ever at Festival of Genomics on spatial stage #spatial #precisionmedicine #singlecell #liquidbiopsy #multiomics #genomics #proteomics

Enjoyed writing this Preview in @CellGenomics with @JGudera on GoT-Multi 🪄 A powerful #singlecell approach from the teams of @AnnaEnim and @LGMartelotto Preview: cell.com/cell-genomics/… Paper: cell.com/cell-genomics/…

Awesome preview of our GoT-Multi by @bloodgenes and @JGudera! —> @AnnaEnim GoT Queen! Charting clonal evolution and behavior with GoT-Multi: Cell Genomics cell.com/cell-genomics/…

@LGMartelotto Thank you @LGMartelotto! We still miss you at HMS. Don’t miss the back-to-back paper from Linas Mazutis reporting on another realization of the CAGEs/capsules.

I remember seeing the very first tests in this magical work… Amazing science from ⁦@KleinLabHMS⁩ Multistep genomics on single cells and live cultures in subnanoliter capsules | Science science.org/doi/10.1126/sc…

Another realization of the CAGEs…from the Linas Mazutis lab!!! 🙌💪👏 science.org/doi/10.1126/sc…

Time is ticking! Make sure you grab your ticket for #FOG2026 before it’s too late! With over 360 expert speakers covering all things #genomics and #biodata, this is an incredible opportunity to network and discover what’s new. Check out the agenda here: hubs.la/Q03ZQFth0

GESTALT workshop at NextGen Omics, Spatial, & Data US 2026

This is the kinds hacks that will likely revolutionize our molecular tool-box. No limits on what can be done from this point onwards. Thanks @ioavlachos for sharing of with me! Rapid evolution of a highly efficient RNA polymerase by homologous recombination | Nature Chemical Biology nature.com/articles/s4158…

The Festival of Genomics & Biodata in London 2026 ti.to/front-line-gen…

RT @LGMartelotto: Join us to the last #GESTALT seminar of one year! Register: broadinstitute.zoom.us/meeting/regist… The GESTALT Seminar Series Time:…