Mathijs Sanders

Extremely grateful for receiving the EHA advanced research grant! Looking forward delving deeper into the disease mechanisms underlying AML. Congratulations to all EHA award winners! #EHA2024 @EHA_Hematology @ErasmusMC @erasmusmcblood

Delighted to share our latest on longitudinal methylation dynamics preceding cancer. Epigenetic signs of AML appear in blood DECADES before Dx. By brilliant @__AFonseca ✅Early cancer ✅Methylation drivers ✅Epimutation rates ✅CpG lineage tracing biorxiv.org/content/10.110…

Read the commentary: Putting AML Differentiation States on the BoneMarrowMap, by Jonas Berger and Livius Penter, online now concurrent with #AACR25. doi.org/10.1158/2643-3…

longcallD is a new variant caller for genomic long reads. It jointly calls phased small and structural variants. Single binary, one command line for the whole process. Comparable accuracy to mainstream callers. Great work by Yan Gao. github.com/yangao07/longc…

The stomach is an organ unique in its function, environment and exposures. How does this affect the mutations that normal cells in the stomach acquire? What does this reveal about the origins of stomach cancer? These questions and more in our Nature paper: nature.com/articles/s4158…

Applications for #TRTH2026 are now open! Are you an early-career researcher in translational hematology? The EHA-ASH TRTH program provides a unique opportunity to enhance your research skills with guidance from leading international experts. 🔹 Applications open today, March 15! 🔹 Deadline: June 26, 2025, at 11:59 PM ET Don’t miss this chance to advance your career in hematology research. Apply now! Learn more: eha.fyi/ashehaTRTH Apply now: eha.fyi/registerTRTH #HematologyResearch #CareerDevelopment #TRTH #TRTH2026

@SylvieNoorderm1 Congrats Sylvie!!

Honored and happy to be elected into the EMBO YIP community. This could not have happened without the great work of my lab members. Immensely grateful to work with them everyday! embo.org/press-releases…

@EarlyCancerCam @jrblundell Congratulations Jamie! Well-deserved!

👏Congratulations to @jrblundell on his election to the Ursula Zoellner Professorship of Cancer Research within the Department of Oncology, highly deserved! 👉earlycancer.cam.ac.uk/news/dr-jamie-…

07 October 2024 at 16.00 CET Erasmus Hematology Virtual Lecture. We have: Kellie Machlus, Boston Children’s , with "Unraveling roles for megakaryocytes beyond platelet production through novel model systems" Spread the news! us06web.zoom.us/j/82722159417 @theclotthickens

Today, we have Alexander Bick presenting! Don't miss it. 23 September at 16.00 CET Title: "Clonal hematopoiesis: causes, consequences and management" Link: us06web.zoom.us/j/82722159417

@JurjenVersluis @JCO_ASCO Congrats Jurjen!

Excited to share our latest study in @JCO_ASCO on improving risk stratification for older patients (≥60 yrs) with Acute Myeloid Leukemia (AML)! We developed a novel prognostic model: AML60+. #Leukemia #AML link: ascopubs.org/doi/full/10.12… 🧵1/9

Our single-cell, pan-cancer analysis of open chromatin in human cancers, done in collaboration with TCGA and the Chang and Corces labs (among others including Illumina), is out in Science today. Congrats to Laksshman Sundaram and all authors! science.org/doi/10.1126/sc…

New review by @sjfhermans, @niek_maas, @JurjenVersluis and others, detailing how real-world data can be of added value if collected and used appropriately!

@PeterLyLab @CellCellPress @UTSWGradSchool @JustinEngel17 Congratulations @PeterLyLab and @JustinEngel17, well-deserved!!!

🚨 Excited to share our latest paper in @CellCellPress identifying how under-replicated chromosomes in micronuclei become shattered by the Fanconi anemia pathway during mitosis. This work was led by @UTSWGradSchool student @JustinEngel17. 🧵 (1/13): cell.com/cell/fulltext/…

Join us! The Machado Lab at @Cambridge_Uni is looking for an enthusiastic RA to be a core member of the team and lead the lab's data generation efforts, seeking to understand how tumour and immune cells co-evolve and contribute to cancer progression. jobs.cam.ac.uk/job/47922/

@PolonenPetri @CMullighan @Nature Congratulations Petri!! Wonderful work!

Interested in non-coding alterations, large-scale genomics, leukemia? Collaboration between @CMullighan and Teachey labs. Genomic analysis of >1300 WGS/WTS/WES samples from T-lineage acute lymphoblastic leukemia, out now in @Nature nature.com/articles/s4158… Highlights (7):

Peter Campbell leaves the Sanger Institute at the end of the year to become Quotient's CSO. A mentor and one of my favourite scientists. His foundational, profound and creative contributions to cancer genomics and somatic evolution have truly shaped those fields. [1/7]

Proud of the review by Roger Mulet-Lazaro on "Oncogenic Enhancers in Leukemia" in Blood Cancer Discovery in August issue. Great stuff for teaching! aacrjournals.org/bloodcancerdis… @RogerMulet @BCD_AACR