Steven Hancock

The second paper from my PhD is finally out in @NatureMicrobiol! TraDIS on IncC conjugation. Thanks to @pmduy, @LabSchembri. Some really cool structural biology by Lou Zhenyao and Bostjan Kobe. nature.com/articles/s4156…

Very excited to share our work on NMEC led by @nhunguyen2811 (under review by eLife). We highlight that even with appropriate antibiotic treatment, causative NMEC that resides intestinally might not be eliminated and can cause relapse. medrxiv.org/cgi/content/sh…

@kaczmarski_joe This is neat. Is it possible to add functionality for showing domains? Colouring and labelling. Is there a way to show a deletion in the centre of the protein?

We discussed shipping strains today and it was surprising to me how much of it is still done in LB agar stabs. That is risky if genomic integrity matters - see paper below and this short thread 🦠📬👇🏼. 1/4 bmcmicrobiol.biomedcentral.com/articles/10.11…

"Climbing has a weight problem." Read more in the article below 👇 climbing.com/news/ifsc-medi…

Abstract submission is open for the 2022 Focused Meeting, Protein Secretion at the Host–Pathogen Interface, taking place 3–4 November in Belfast. Submit your abstract before 15 July. microb.io/3uF3YT3 #HostPathSecretion22

PRETTY COOL STUFF on WaaL, the O-antigen ligase for building LPS. These folks were amazing to work with! @pippomancia @Khuram_U_Ashraf @RieNygaard @davidroper2 @ChrisLBGraham @OliBClarke @meagandufrisne @VasileiosPetrou & others nature.com/articles/s4158…

Diversity and distribution of type VI secretion system in bacterial plasmids. assets.researchsquare.com/files/rs-13214…

We are looking for a postdoc or research associate/technician to join a multidisciplinary team on an antibiotic discovery project combining high-throughput microscopy, imaging AI, and chemical AI. See bit.ly/3F854La. Apply at brunABdiscovery@gmail.com.

Our research shows that efficacy of tetracycline class antibiotics can be restored to treat MDR Acinetobacter baumannii infection. Great collaborative effort @fordebm @LabSchembri @davidantibiotic @mark_blaskovich @camcdevitt @MarkvonI journals.asm.org/doi/10.1128/mb…

Political interference in the selection of research grants is eroding Australia’s international reputation and the integrity of Australia’s research system. Of the 4 known occurrences of political interference, 3 have occurred in the last three years. science.org.au/news-and-event…

Still time to apply for a PhD project in my lab to investigate the interface between K. pneumoniae T6SS and macrophages. Fun project in an international and supportive environment.findaphd.com/phds/project/d…

We search a #PhD student to join the team. Exciting, interdisciplinay project investigating new host defence mechanism and their subversion by #bacteria (#Legionella) @WWIEM_QUB. #microbiology #cellbiology #biochemistry findaphd.com/?pj=139820 DM me for info. RT please!

What factors are required for bacterial fighting? Our latest study in @NAR_Open shows that the H2-T6SS and its effectors requires the regulators Sfa2 and RpoN in #Pseudomonas Great work @AlColls Eleanor @towo_towo @FillouxLab @CMBI_Imperial @ImperialNHLI academic.oup.com/nar/advance-ar…

RpoN/Sfa2-dependent activation of the P. aeruginosa H2-T6SS and its cognate arsenal of antibacterial toxins. @luke_allsopp @towo_towo @FillouxLab academic.oup.com/nar/advance-ar…

Please RT: We are looking for a postdoc or research associate/technician to join a multidisciplinary team on an antibiotic discovery project combining high-throughput microscopy, imaging AI, and chemical AI. See bit.ly/3F854La. Apply at brunABdiscovery@gmail.com.

Merry Christmas from the Bakery! bit.ly/3yIGHkB Our first combined wet and dry lab work - why has one AMR plasmid globally disseminated among Shigella and another has not? Led by @MalakaDes with @Jaws_Stenhouse @GraceBlackwel1 @RJBengtsson @ClaireJenkins2 @JPJHall

Many thanks to everyone involved for the hard work and to the anonymous reviewers for the very constructive comments! journals.plos.org/plospathogens/…

The plasmid gene aac(6’)-Ib-cr confers 4x increase in MIC to cipro in strains already harbour resistant gyrA and parC mutations. This dual resistance combination shows strong association with emerging carbapenem resistant clones. journals.asm.org/doi/10.1128/AA…

Excited to announce that the 661K resource is now live at Plos Biology @PLOSBiology journals.plos.org/plosbiology/ar… We uniformly assembled, ran quality control and performed general characterisation on 661,405 bacterial genomes that were in the ENA at the end of November 2018.