Timothy Dreyer

Cover image showing pseudo-colored trabeculae of the Sost -/- proximal tibiae, highlighting how bone thickness varies, measured by µCT. This cover image was contributed by @DrScottJRoberts , the Royal Veterinary College, London, UK.🥳 @BoneRes_Office nature.com/articles/s4141…

Scientists are testing a new drug, LGK974, to treat sclerosteosis—a rare disease that causes dangerously dense bones and serious health issues. Early results in mice show it may help reduce bone overgrowth without surgery!😁 #bone @DrScottJRoberts nature.com/articles/s4141…

📋 Importance: LGK974 therapy would likely be an option for early disease treatment in children, potentially avoiding risky surgical treatments and providing massive relief to these patients and their families. @RareDiseases @RareRevolutionM @rarediseasessa @RareBeacon

💊 What We Found: A drug called LGK974 reduced skull and ear bone mass of young mice with #sclerosteosis, indicating that it effectively limits skeletal overgrowth at sites with severe/fatal pathology.

New drug targets #sclerosteosis, an ultra-rare, potentially fatal bone disease: nature.com/articles/s4141… Identifying the drug (LGK974) as a much-needed potential sclerosteosis treatment is a significant step forward for patients with this #raredisease.

🚨 IT'S RARE DISEASE DAY GLOBALLY! 🚨 Join us marking #RareDiseaseDay 2024! Spread awareness, share stories, and support those living with rare diseases. Together, we make a lasting impact! #ShareYourColours

⏰ Just one day to go until #RareDiseaseDay 2024! #DidYouKnow there are 6000+ known rare diseases? Visit rarediseaseday.org for key statistics on rare conditions. 🦓 #ShareYourColours

Our group from @RoyalVetCollege representing rare disease research at this month's #ORS2024 where @TimmyJDreyer presented on therapeutic discovery for Sclerosteosis. Remembering that there is so much work left to do, on #RareDiseaseDay - onwards to a cure!

Two fantastic podium presentations and an excellent poster presentation from our lab @RoyalVetCollege during #ORS2024. Congratulations @LeahWells961, @TimmyJDreyer and @alpacamanpriv - you have all knocked it out of the park! Very proud PI here 🙂 #drugdiscovery #skeletal

Great evening talking about everything musculoskeletal - from canine osteoarthritis, to why astronauts lose bone, and the ultra rare human disease sclerosteosis #NightAtTheVetCollege @RoyalVetCollege with @TimmyJDreyer

A new form of expansion microscopy called ChromExM can be used to expand chromatin to visualize transcription at high resolution, according to new research in Science. Learn more ⬇️ 📄: scim.ag/3kG #SciencePerspective: scim.ag/3kF

What a fantastic achievement! @LeahWells961, @alpacamanpriv and @TimmyJDreyer with New Investigator Awards, and @DrSarahBoneBiol with the Best Basic Oral Award at the @BoneResearchSoc Annual Meeting in Manchester. Well done guys - you are stars🌟 @RoyalVetCollege #bone #research

@TimmyJDreyer joined #BoneUP #Live to talk about #sclerosteosis An ultra rare genetic bone condition #BRS22 #BRS2022 @BoneResearchSoc

💜 We are delighted to retain our top ranked position in veterinary science again in the QS @worlduniranking 2022 #1VetScience #QSRankings #StillMakingHistory ➡️ Read more at: rvc.uk.com/qs-rankings-20… ➡️ Share and celebrate at: rvc.uk.com/celebrate

Looking forward to working with this super talented team along with RVC and UCB colleagues on this exciting project! #ankylosingspondylitis #sclerosteosis

“I’m dreaming of an osteocyte christmas”🎄🦴 #TeamBioGingerbread @BioRender @DrScottJRoberts @alpacamanpriv @TimmyJDreyer

@Plusnet good day, how can I change my router delivery address? I've emailed support 2 days ago, but received no response. Router is slated for delivery today, but I won't be at home to receive it until after 5pm. Thank you.

Only a few days left to apply for this postdoc position, come work on understanding skeletal disease with us 🙂