Zoë Steier
28 posts
Zoë Steier
@zsteier
Postdoc with @shaleklab at @MIT/@broadinstitute. Former PhD with @YosefLab and @airstreets at @UCBerkeley/@BerkeleyBioE.
Cambridge, MA เข้าร่วม Ağustos 2014
14 กำลังติดตาม107 ผู้ติดตาม
Zoë Steier รีทวีตแล้ว
From the Robey (MCB), Streets (BioE), and Yosef (EECS) labs. We used single cell multiomics to provide a new perspective on one of the most intensely studied mammalian cell fate decision: the helper vs killer T cell fate decision. nature.com/articles/s4159…
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Check out our work, now published in @NatImmunol! nature.com/articles/s4159…
Zoë Steier@zsteier
I am pleased to share the last major work of my PhD in the labs of @airstreets and @YosefLab, in collaboration with @LabRobey, Laura McIntyre, and @LydiaLutes. We used CITE-seq with totalVI analysis to study the drivers of CD4/CD8 T lineage commitment./1 biorxiv.org/content/10.110…
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I'm very happy to announce that I'll be joining @Stanford's Department of Genetics as a tenure-track Assistant Professor! The Altemose Lab will officially open in 2023 (after I finish my current postdoc at UC Berkeley), but I can't wait to get started! altemoselab.org /1
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Thanks as well to @BioE_BEAST, @BerkeleyBioE, @Cal_Engineer, and @SiebelScholars for your support. And thanks especially to my wonderful advisors Aaron and Nir for this incredible opportunity to contribute to such an exciting, multi-disciplinary effort throughout my PhD./10
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An especially rewarding aspect of this work was pushing beyond atlas-style analysis to investigate a developmental mechanism: we generated a hypothesis through computational analysis and validated it experimentally. Thanks to the entire team that made this possible./9
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I am pleased to share the last major work of my PhD in the labs of @airstreets and @YosefLab, in collaboration with @LabRobey, Laura McIntyre, and @LydiaLutes. We used CITE-seq with totalVI analysis to study the drivers of CD4/CD8 T lineage commitment./1 biorxiv.org/content/10.110…
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@SarahJRockwood @CalTriathlon Thank you @SarahJRockwood! I have great memories of talking about research and PhD/MD goals while biking up Wildcat. Congratulations to you too!
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Congrats @zsteier!! Amazing to see how your research that we talked about on @CalTriathlon bike rides has made such an impact!
Aaron Streets@airstreets
I am very happy to congratulate and celebrate @NAltemose and @zsteier, the first two PhD students to graduate from my lab!
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Zoë Steier รีทวีตแล้ว
Excited to share a more formal look at our work on scvi-tools, in which we describe an overview of the codebase and new features. We hope scvi-tools will set a community standard for the deployment of probabilistic models in single-cell omics
biorxiv.org/content/10.110…
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Zoë Steier รีทวีตแล้ว
TotalVI: A transformative algorithm | Researchers have invented a computer algorithm that uses deep learning to integrate gene and protein data about single cells: bit.ly/3w5vI3i.
@UCBerkeley #BerkeleyEngineering
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@timtriche @adamgayoso @airstreets @YosefLab @_romain_lopez_ Hi Tim, we did not do any enzymatic digestions on the spleen or lymph nodes, just mechanical dissociation (see "Cell Preparation" in the Methods of the published version: nature.com/articles/s4159…).
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Excited to introduce totalVI for end-to-end analysis of CITE-seq data! (@zsteier @airstreets @YosefLab @_romain_lopez_ )
biorxiv.org/content/10.110… /1
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Thrilled to share that #totalVI (our method for joint analysis of CITE-seq data) is now published in @naturemethods! It has been a fantastic collaboration with @airstreets, @YosefLab, and my co-first author @adamgayoso. Check out the tutorials on scvi-tools.org.
Nature Methods@naturemethods
Total Variational Inference is a framework for end-to-end analysis of paired transcriptome and protein measurements such as CITE-seq data in single cells from the Streets and Yosef labs. nature.com/articles/s4159…
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