Jae Lab

Big news this week: results of a very competitive @ERC_Research CoG call are in, and I’m happy that our project mitoSCALES (scales of mitochondrial stress response) is among the ~11% funded. Recruiting will begin soon—get in touch if you want to hop on board for the ride! #ERCCoG

@DeshwalSoni @HelmholtzMunich @ERC_Research @Conrad_Lab @SchmollerLab @NatalieKrahmer Cool! Congratulations and welcome to Munich

I am very happy to announce that I will be joining @HelmholtzMunich as a group leader from January 2025. Looking very much forward to work with my new colleagues on Ferroptosis and mitochondria #ERCStg @ERC_Research @Conrad_Lab Fabiana Perocchi @SchmollerLab @NatalieKrahmer

@BarteltLab Congrats, wonderful news! 🤩

🚨Job update🚨 THRILLED to announce that today, I was appointed as the new Else Kröner Fresenius Full Professor and inaugural Chair of Translational Nutritional Medicine at Technical University Munich 🤓🍾🥂❤️☀️ O’zapft is!

📣Only three weeks left to apply! Exciting projects with renowned scientists are available. Don’t miss your chance! qbm.genzentrum.lmu.de/application/ @TheJaeLab @karen_alim @PhysOfLifeLMU @hornung_lab @khmelinskaia @LFMilles @SchwilleLab @RaedlerLab @BenediktSabass

Having a hard time with #CRISPR HDR? Your cells might be fighting against you! TREX1 nuclease, high in some cells, eats up HDR donor templates. Check out our paper in @NatureBiotech for the story & ways to improve HDR. nature.com/articles/s4158… With @karasuerman1 & @J_Maciejowski

🥳🚨Paper Alert🚨🥳 Excited to present our latest work on #Opa1 in this newly published paper @ScienceAdvances by @sahola6 and @LPazurek. We present here two new mouse models with impaired Opa1 processing. 1/🧵 science.org/doi/10.1126/sc… #mitochondria #mitochondrialdynamics @MPIAGE

Don’t miss this great opportunity! Deadline is September 13.

🚀Our celebratory symposium last Monday was enjoyed by all participants😀😆. Bavarian Minister of State Blume and LMU President Huber offered their congratulations. Patrick Cramer, President of the Max Planck Society, sent his greetings via video message.

There is a new study section @GBM_eV @JuniorGBM on Organelle Biology and I have just joined - exciting initiative by @winklhofer_lab & @Herrmann_lab and very relevant for our new @dfg_public Priority Program

@ThijnBrummel Congrats, Thijn! Powerful stuff! #HaploidGenetics

How does DNA damage cause apoptosis when p53 is mutated? Critical to understand treatment of many tumors. Excited that ‘DNA damage induces p53-independent apoptosis through ribosome stalling’ by Nicolaas Boon and collaborators is out: doi.org/10.1126/scienc…

Excited to share our latest study in @ImmunityCP showing how PLD exonucleases together with RNase T2 process RNA upstream of TLR7. ✂️🧬 Kudos to @BeroutiMarleen for her fantastic work! cell.com/immunity/fullt…

Our paper on functional discovery of protein degradation and stabilization effectors with proteome-scale induced proximity screens is out in its final version! 1/ nature.com/articles/s4158… rdcu.be/dBUju

Looking for a postdoc position to study epithelial tissue dynamics in Drosophila? New institute, interdisciplinary, international environment and very livable place @uni_muenster One week left to apply, see thenode.biologists.com/jobs/postdoc-p…

Let's do the right click! In chemical proteomics chemoselectivity of the CuAAC is crucial. Andreas Wiest in our group found that formation of the ubiquitous thiotriazole byproduct during the click reactions can be easily diminished: pubs.acs.org/doi/10.1021/ja…. Congratulations!

📣📣📣Great opportunity for ambitious junior researchers🫵 We are looking for an Independent Group Leader in Nucleic Acid Research🧬 genzentrum.uni-muenchen.de/career/group_l… Please RT🙏 #ApplyNow #Career

@KivancBirsoy @ScienceMagazine @YuyangLiu1996 @RockefellerUniv @TheMarkFdn Fantastic! Congratulations @KivancBirsoy and team!!

How does mitochondria sense and control their glutathione levels? Our new work @ScienceMagazine by a fantastic student @YuyangLiu1996 describing a redox metabolite sensing mechanism for mitochondria. @RockefellerUniv @TheMarkFdn science.org/doi/10.1126/sc…

📢Don't miss this publication by the @hornung_lab Congratulations to all people involved👏🥳 β1 integrin signaling governs necroptosis via the chromatin-remodeling factor CHD4: Cell Reports cell.com/cell-reports/f… @LMU_Muenchen @237Crc @sfb_1403

Do cells care if their mitochondrial DNA is broken? Yes! Excited to share my PhD work showing that a fraction of cells with breaks in their mtDNA recover healthy mitochondria using the integrated stress response.

🥳🤩To our delight, Gonca Çetin @TheJaeLab has won a fellowship from the Peter und Traudl Engelhorn Stiftung. She will be supported for 2 years to investigate the integrated stress response in human cells. Congratulations, Gonca🎇🥂 engelhorn-stiftung.de #Research #postdoc