Jagan Mohan R., MD

@Saboo_Shubham_ Who else finds these large libraries of repositories overwhelming? So many tools (and toys) and so little time.

Golden age of Open source AI. 100+ AI Agents, multi-agent teams and RAG templates. 100% free and Open Source (105,000+ GitHub stars already). github.com/Shubhamsaboo/a…

The CEO of Google DeepMind just admitted that if the decision had been his, we would've cured cancer before anyone ever used ChatGPT. And that's not even the scariest thing he said on a recent interview. Demis Hassabis is one of the most important people alive in AI. He won the Nobel Prize last year for AlphaFold, the system that cracked the 50 year protein folding problem. 3 million scientists now use his tool. Almost every new drug being developed will touch it at some stage. In a new interview, he was asked about the moment ChatGPT launched and Google went into "code red." His answer was one of the most revealing things any AI leader has ever said on the record: "If I'd had my way, I would have left AI in the lab for longer. Done more things like AlphaFold. Maybe cured cancer or something like that." Read that again. The man running Google's entire AI division is publicly saying the commercial AI race we're all living through was a MISTAKE. That the industry got hijacked by a chatbot when it could have been solving the biggest problems in science and medicine. His vision was simple: Build AI slowly, carefully, like CERN. Use it to crack root node problems one at a time. Cancer. Energy. New materials. Let humanity benefit from real breakthroughs while the foundational science was figured out over a decade or two. Then ChatGPT dropped in November 2022 and everything changed. Demis described what happened next as getting locked into a "ferocious commercial pressure race" that none of the labs can escape from. On top of that, the US vs China dynamic added geopolitical pressure. The result is everyone sprinting toward products instead of breakthroughs, shipping chatbots while the scientific opportunity gets buried under marketing cycles and quarterly earnings. But he's not saying progress isn't happening... He's saying the progress got redirected away from the things that actually matter most. And then it got even scarier: Because when Demis was asked what he worries about with AI, he laid out two threats. The first is what everyone talks about: Bad actors using AI for harm. Terrorist groups. Hostile nation states. Cyberattacks at scale. But that's not the threat he's most worried about. His second worry is AI itself going rogue. Not today's models. The models coming in the next two to four years as the industry enters what he calls "the agentic era." Systems that can complete entire tasks autonomously. Systems that are increasingly capable and increasingly hard to control. His exact words: "How do we make sure the guardrails are put in place so they do exactly what they've been told to do, and there's no way of them circumventing that or accidentally breaching those guardrails? That's going to be an incredibly hard technical challenge if you think about how powerful and smart and capable these systems eventually get." A Nobel Prize winner who runs one of the 3 most advanced AI labs on Earth just said publicly that within two to four years, we're entering a phase where AI alignment becomes a real problem, and the technical challenge of solving it is enormous. And almost nobody is paying enough attention. He called for international cooperation between labs, AI safety institutes, and academia to tackle the problem. He said this is the thing even the experts aren't thinking about enough. He said the only way to get through the AGI moment safely is if everyone starts treating this with the seriousness it deserves. Most AI CEOs give you careful PR answers about "responsible development" and move on. Demis said something different... He said the commercial race FORCED us into a premature deployment of a technology we barely understand, and the window to get alignment right before the next generation of agents shows up is two to four years. If the man who built the system that might cure cancer is telling you he wishes it had happened first, maybe we should listen to what he says is coming next.

@DefiantDevii Here an introspection for the types of you. Get. Off. Your. Asses and do something useful rather than distributing gyan to all Indians on X from your couch. It is the most useless people in society who tend to be the superlative preachiest.

Sometimes Indians need to ask themselves if they see any benefit in their personal lives in being a citizen of the world’s 4th largest economy. Does this chest thumping actually translate to anything meaningful in your life? Be introspective.

@jsdass1978 @OfficialJipmer @UDF_BHARAT @rxpg_jipmer @JipmerRDA @Indian__doctor @IMAIndiaOrg @DrVish355 @VishnuRajgadia @pondicherryinfo @THPondy Easily fixed by using a face biometric device to punch in and punch out of duty hours.

Hi all fellow Indians & doctors, beware of JIPMER on PG course. JIPMER doesn’t not maintain duty hours & week off data of JRs which means they have a lot to hide such as cruel illegal 24-36 hours duty and no week off. Don’t get deceived by rankings. PG ragging is high in JIPMER

@HowToAI_ At last, I can justify buying a 3D printer to my wife.

🚨 Someone just connected Claude directly to blender. you can now build complex 3d models and geometry just by typing a text prompt.

@dr_cintas @opera_neon_ Opera! I remember the years when it was the greatest, until chromium stole its lunch. What happened to claude in chrome?

Claude Code can now operate inside your actual browser🤯 @opera_neon_ just became the first browser with a built-in MCP connector What Claude gets access to: → Your open tabs → Your authenticated sessions → Live page content, forms No sandboxed simulation. Your real session

@R_N_Vaghani So what's stopping you from pursuing agriculture? There is no dearth of whiny sad people lamenting zero tax on agriculture, as if it is gated somehow. Agriculture employs half of India. When an industry does that, it deserves to become tax-free for that value addition alone.

If you earn 5 crores from agriculture, you pay 0 tax. If you earn 30 lakhs from salary, you pay 8 lakh tax Hmmmm......

@neural_avb No Remotion?

Damn I am vibecoding something that's gonna help me so much to produce tutorial content faster opentui + ipykernel + vim motions + ffmpeg A jupyter notebook directly in my terminal that will auto run code and create an mp4 from... No need for me to physically screen record anymore after this!

@paraschopra This is so common now a days. Opencode has 'go' plan. 5 usd/month. opencode.ai/go

Steal this idea. Openrouter but with a fixed fee instead of extra 5.5% they charge. Having a single interface for all models is amazing, but charging variable cost for proxying requests seems excessive. Why not charge on per-user basis instead of 5.5% of all spend?

@DrVish355 Dentists are jumping in on the game. More the merrier. Oh, don't forget, the gene therapy for baldness is just right around the corner, so I wouldn't bet much on hair transpant skills though.

Dear dermatologists ,focus on your hair transplant skills. In just a few years, India will overtake Turkey as the global hub for hair transplants.

@Ravisutanjani Richer municipalities with budgets for waste disposal. Plus commonsense civic sensibilities. If you really want Singapore style, the solution is simple: Fine heavily, share the fine with those who report with evidence. Have citizens enforce the law with skin in the game.

🚨 What Will Make Indian Cities Cleaner? Dubai, Singapore, Japan Roads Look Spotless Primary Reason Is Strict Law Enforcement And Better Civic Responsibilities By Citizens India Badly Needs To Fix Both For Improvement

@farzyness Hermes - you can run it on serverless architecture. I run it on railway. That's the biggest pro.

People who have extensively used OpenClaw and Hermes: Please give me your most honest assessment of pros and cons between the two below.

@plainionist > humans can't read but AI can, Ever heard of machine language? Modern programming languages were abstracted layer for machine language. And now, ordinary English has become that abstraction layer.

Serious question: If vibe-coded projects produce code humans can't read but AI can, do we end up depending on AI just to maintain our own systems? 🤔

@DrSuneelDhand I think AI will spare primary care family doctors - in fact, resurrect them from irrelevance and bring them back. We have seen this before. Too much information overload leads to indecisiveness. We need patient advocates - aka family physicians.

The medical specialties most likely to be replaced by AI next few years: 1. Primary care doctors 2. Radiologists 3. Dermatologists 4. Psychiatrists 5. Ophthalmologists Least likely: Surgeons (although it’s still on the horizon) Did I miss any?

@ihtesham2005 And when your project root is just an empty folder? What use is skills when you have built enough for autoskills to then stroll in and install for 50+ technologies?

I will never set up skills manually again. Someone open-sourced a single command that scans your project, detects your entire tech stack, and installs the right AI agent skills for everything it finds automatically. It's called autoskills. You run `npx autoskills` in your project root. That's it. → Reads your package.json and config files to fingerprint your stack → Matches detected technologies against a curated skill registry at skills.sh → Installs skills for 50+ technologies: React, Next.js, Vue, Svelte, Astro, Tailwind, Supabase, Neon, Playwright, Expo, Stripe, Prisma, Cloudflare, AWS, Vercel, GSAP, Bun, Deno, Hono, NestJS, Spring Boot, and more → `--dry-run` flag shows what it would install before touching anything One command. Your entire AI skill stack. Installed. Link in the comments.

@kumarmanish9 Well, educated ministers is no guarantee of performance. In fact, technocracy has always regressed into tyranny, the fastest. All models agree: education has little to no relevance to ministerial performance. Technocratic bureaucracy controlled by ordinary politicians OTOH....

#Nepal rubbing salts on the wounds by appointing educated and qualified professionals backed with professional degrees to do the ministerial job. Best wishes to Nepal for this experiment.

@DramaIsMyAura Sanskrit or Pali.

One language you wish you could speak fluently?

@Saboo_Shubham_ So many tools, harnesses, frameworks, workflows... We need somebody to take deep dives into these, work with them for a week (long time in AI) and get back with results.

Someone just dropped an open source alternative to Claude Managed Agents. Install the CLI, create an agent, assign a task. It automatically shows up on the board like any other team member. It works with Claude Code, Codex, OpenClaw and OpenCode.. 100% Open Source.

@jaredrhoads How about.. An arXiv for biomedicine. No journals. Just decentralized peer review driven by a curated, randomized voting community to prevent brigading and academic cabals. It is time to dismantle the legacy publication model and let scientific merit stand entirely on its own.

Hear me out: Common App, but for submitting manuscripts to journals. (Submit one place. Journals claim. Authors have 12 hours to accept or hold out.)

@RishiBhattach @pushpendrakum This is the right answer in form of the most fundamental question.

@pushpendrakum Why? Who are you to decide if my kid prefers studying private or govt?

Should India take a bold step like Nepal and shut down private schools? 🤔 Because right now, “education” in many private schools feels more like organized loot than learning. Sky-high fees, hidden charges, zero accountability… Parents are paying premium, but are students really getting premium education? Time to ask: Are we building minds or just running a business? 🚨